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| Morten Nielsen Lektor |
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DTU Systembiologi
Institut for Systembiologi
Center for Biological Sequence Analysis, Immunological Bioinformatics
Danmarks Tekniske Universitet
Kemitorvet
Bygning 208, rum 15
2800 Lyngby
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Forskningsprofil.
Min primære forskning er fokuseret omkring udviklingen af nye
algoritmer for mønstergenkendelse til brug for beskrivelse af
centrale egenskaber af immune hos mennesker og dyr samt
forskellige aspekter af protein struktur. Min forskning indenfor
udviklingen af nye algoritmer har som det primære formål at
konstruere metoder der kan forbedre vores muligheder for at lave
rationelt vaccine design mod humane og dyre infektioner så som
HIV, Tuberculosis, Malaria, og mund og klovsyge. De algoritmer
jeg har udviklet indeholder Gibbs sampler, kunstige neurale
netværk, positions specifikke scorings matricer, sekvens
clustering, hidden Markov models samt sekvens-profil baserede
alignment metoder. Som en central del af min seneste forskning
har jeg startet den store indsats fra vores forskningsgruppe
indenfor karakteriseringen af diversiteten af immunsystemet hos
mennesker og andre primater samt den genomiske variation af
pathogen infektioner. Denne forskning har givet os nye centrale
værktøjer, der gør os i stand til i en langt højere grad end
hidtil at forstå hvorfor forskellige mennesker (og dyr) reagerer
forskelligt på forskellige patogene
infektioner.
Min stærke interesse for beskrivelsen og udviklingen af
algoritmer med bruge indenfor bioinformatik har ført til, at jeg
har udviklet et kursus med speciale indenfor netop dette emne.
Kurset, Algoritmer i bioinformatik (27623) løber hvert efterår
startende 2008. |
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Year |
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in journal: Molecular Immunology (ISSN: 0161-5890) (DOI: http://dx.doi.org/10.1016/j.molimm.2012.06.001), vol: 53, issue: 1-2, pages: 24-34, 2013
Type:
Journal article - Journal article
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2013 |
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part of: Antigen Processing (ISBN: 978-1-62703-217-9), pages: 247-260, 2013,
Type:
Book chapter - Book chapter
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2013 |
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in journal: Animal Genetics (ISSN: 0268-9146) (DOI: http://dx.doi.org/10.1111/j.1365-2052.2012.02400.x), vol: 44, issue: 3, pages: 251-258, 2013
Type:
Journal article - Journal article
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2013 |
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in journal: Immunogenetics (ISSN: 0093-7711) (DOI: http://dx.doi.org/10.1007/s00251-011-0579-8), vol: 64, issue: 3, pages: 177-186, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: Expert Review of Vaccines (ISSN: 1476-0584) (DOI: http://dx.doi.org/10.1586/erv.11.160), vol: 11, issue: 1, pages: 43, 2012
Type:
Journal article - Journal article
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2012 |
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part of: Molecular Immunology, pages: 11, 2012, Elsevier,
Type:
Conference abstract in proceedings - Conference abstract in proceedings
Presented at:
7th International EMBO Workshop on Antigen Presentation and Processing, Amsterdam
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2012 |
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Type:
Conference abstract for conference - Conference abstract for conference
Presented at:
4th European Veterinary Immunology Workshop (EVIW), Edinburgh
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2012 |
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in journal: Immunology (ISSN: 0019-2805) (DOI: http://dx.doi.org/10.1111/j.1365-2567.2012.03579.x), vol: 136, issue: 3, pages: 306-311, 2012
Type:
Journal article - Journal article
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2012 |
Harndahl, Mikkel Nors ; Rasmussen, Michael ; Roder, Gustav ; Dalgaard Pedersen, Ida ; Sørensen, Mikael ; Nielsen, Morten ; Buus, Søren
in journal: European Journal of Immunology (ISSN: 0014-2980) (DOI: http://dx.doi.org/10.1002/eji.201141774), vol: 42, issue: 6, pages: 1405-1416, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: Nucleic Acids Research (ISSN: 0305-1048) (DOI: http://dx.doi.org/10.1093/nar/gks469), vol: 40, issue: W1, pages: W281-W287, 2012
Type:
Journal article - Journal article
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2012 |
Rasmussen, Michael ; Harndahl, Mikkel Nors ; Nielsen, Morten ; Buus, Soren ; Stryhn, Anette
Type:
Conference abstract for conference - Conference abstract for conference
Presented at:
99th Annual Meeting of the American-Association-of-Immunologists, Boston MA
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2012 |
Nene, Vishvanath ; Svitek, Nicholas ; Toye, Philip ; Golde, William T. ; Barlow, John ; Harndahl, Mikkel Nors ; Buus, Soren ; Nielsen, Morten
in journal: Ticks and Tick-borne Diseases (ISSN: 1877-959X) (DOI: http://dx.doi.org/10.1016/j.ttbdis.2011.12.001), vol: 3, issue: 3, pages: 188-192, 2012
Type:
Journal article - Journal article
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2012 |
Buggert, Marcus ; Norstrom, Melissa M. ; Czarnecki, Chris ; Tupin, Emmanuel ; Luo, Ma ; Gyllensten, Katarina ; Sonnerborg, Anders ; Lundegaard, Claus ; Lund, Ole ; Nielsen, Morten ; Karlsson, Annika C.
in journal: P L o S One (ISSN: 1932-6203) (DOI: http://dx.doi.org/10.1371/journal.pone.0039874), vol: 7, issue: 7, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: P L o S One (ISSN: 1932-6203), vol: 7, issue: 9, pages: e38670, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: Animal Genetics (ISSN: 0268-9146) (DOI: http://dx.doi.org/10.1111/j.1365-2052.2012.02400.x), 2012
Type:
Journal article - Journal article
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2012 |
Kim, Yohan ; Ponomarenko, Julia ; Zhu, Zhanyang ; Tamang, Dorjee ; Wang, Peng ; Greenbaum, Jason ; Lundegaard, Claus ; Sette, Alessandro ; Lund, Ole ; Bourne, Philip E. ; Nielsen, Morten ; Peters, Bjoern
in journal: Nucleic Acids Research (ISSN: 0305-1048) (DOI: http://dx.doi.org/10.1093/nar/gks438), vol: 40, issue: W1, pages: W525-W530, 2012
Type:
Journal article - Journal article
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2012 |
Teppa, Elin ; Wilkins, Angela D. ; Nielsen, Morten ; Marino Buslje, Cristina
in journal: B M C Bioinformatics (ISSN: 1471-2105) (DOI: http://dx.doi.org/10.1186/1471-2105-13-235), vol: 13, pages: -, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: P L o S Computational Biology (ISSN: 1553-734X), vol: 8, issue: 12, pages: e1002829, 2012
Type:
Journal article - Journal article
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2012 |
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in journal: Immunogenetics (ISSN: 0093-7711) (DOI: http://dx.doi.org/10.1007/s00251-010-0493-5), vol: 63, issue: 1, pages: 43-55, 2011
Type:
Journal article - Journal article
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2011 |
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in journal: Clinical and Vaccine Immunology (ISSN: 1556-6811) (DOI: http://dx.doi.org/10.1128/CVI.00417-10), vol: 18, issue: 2, pages: 280-288, 2011
Type:
Journal article - Journal article
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2011 |
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