Kira Astakhova

Kira Astakhova

Lektor

DTU KEMI
Institut for Kemi

Kemi: Faculty

Danmarks Tekniske Universitet

Kemitorvet

Bygning 206, rum 118

2800 Kgs. Lyngby

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Publikationer
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2018
 

"Clicking" Gene Therapeutics: A Successful Union of Chemistry and Biomedicine for New Solutions

Astakhova, Kira ; Ray, Roslyn ; Taskova, Maria ; Uhd, Jesper ; Carstens, Annika ; Morris, Kevin
in journal: Molecular Pharmaceutics (ISSN: 1543-8384) (DOI: http://dx.doi.org/10.1021/acs.molpharmaceut.7b00765), 2018

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    År: 2018     |    DOI: http://dx.doi.org/10.1021/acs.molpharmaceut.7b00765

2017
 

New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods

Mulberg, Mads Westergaard ; Taskova, Maria ; Thomsen, Rasmus P. ; Okholm, Anders H. ; Kjems, Jørgen ; Astakhova, Kira
in journal: Chembiochem (ISSN: 1439-4227) (DOI: http://dx.doi.org/10.1002/cbic.201700125), vol: 18, issue: 16, pages: 1599-1603, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1002/cbic.201700125

 

Synthetic Nucleic Acid Analogues in Gene Therapy: An Update for Peptide–Oligonucleotide Conjugates

Taskova, Maria ; Mantsiou, Anna ; Astakhova, Kira
in journal: Chembiochem (ISSN: 1439-4227) (DOI: http://dx.doi.org/10.1002/cbic.201700229), vol: 18, issue: 17, pages: 1671-1682, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1002/cbic.201700229

 

Antisense Oligonucleotides Internally Labeled with Peptides Show Improved Target Recognition and Stability to Enzymatic Degradation

Taskova, Maria ; Madsen, Charlotte S. ; Jensen, Knud Jørgen ; Hansen, Lykke Haastrup ; Vester, Birte ; Astakhova, Kira
in journal: Bioconjugate Chemistry (ISSN: 1043-1802) (DOI: http://dx.doi.org/10.1021/acs.bioconjchem.6b00567), vol: 28, issue: 3, pages: 768-774, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1021/acs.bioconjchem.6b00567

 

Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence

Taskova, Maria ; Uhd, Jesper ; Miotke, Laura ; Kubit, Matthew ; Bell, John ; Ji, Hanlee P. ; Astakhova, Kira
in journal: Analytical Chemistry (ISSN: 0003-2700) (DOI: http://dx.doi.org/10.1021/acs.analchem.7b00646), vol: 89, issue: 8, pages: 4363-4366, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1021/acs.analchem.7b00646

  PDF

Complexes of DNA with fluorescent dyes are effective reagents for detection of autoimmune antibodies

Domljanovic, Ivana ; Carstens, Annika ; Okholm, Anders ; Kjems, Jørgen ; Nielsen, Christoffer Tandrup ; Heegaard, Niels H. H. ; Astakhova, Kira
in journal: Scientific Reports (ISSN: 2045-2322) (DOI: http://dx.doi.org/10.1038/s41598-017-02214-0), vol: 7, issue: 1, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1038/s41598-017-02214-0

 

2'-O-Me RNA probes modified with pyrene fluorophores: Attachment point matters

Astakhova, Kira ; Korshun, V.
in journal: Tetrahedron (ISSN: 0040-4020), vol: 73, pages: 3220-3230, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017

 

Environmentally sensitive molecular probes reveal mutations and epigenetic 5-methyl cytosine in human oncogenes

Taskova, Maria ; Barducci, M. C. ; Astakhova, Kira
in journal: Organic and Biomolecular Chemistry (ISSN: 1477-0520) (DOI: http://dx.doi.org/10.1039/c7ob01147d), vol: 15, issue: 27, pages: 5680-5684, 2017

Type: Journal article

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1039/c7ob01147d

2016
  PDF

Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases

Samuelsen, Simone V. ; Maity, Arindam ; Nybo, Mads ; Macaubas, Claudia ; Lonstrup, Lars ; Balboni, Imelda M. ; Mellins, Elizabeth D. ; Astakhova, Kira
in journal: P L o S One (ISSN: 1932-6203) (DOI: http://dx.doi.org/10.1371/journal.pone.0156125), vol: 11, issue: 6, 2016

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: http://dx.doi.org/10.1371/journal.pone.0156125

  PDF

Revealing Nucleic Acid Mutations Using Forster Resonance Energy Transfer-Based Probes

Junager, Nina P. L. ; Kongsted, Jacob ; Astakhova, Kira
in journal: Sensors (ISSN: 1424-8220) (DOI: http://dx.doi.org/10.3390/s16081173), vol: 16, issue: 8, 2016

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: http://dx.doi.org/10.3390/s16081173