Postdoc: Physical Aspects of Developing System for Fast Sepsis Diagnosis

DTU Nanotech
Friday 19 Oct 18

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DTU Nanotech conducts cross-disciplinary research where micro- and nanotechnology is applied to a wide range of scientific disciplines, e.g., mechanics, optics, chemistry, medical technologies and biotechnology. The BioLabChip group at DTU Nanotech invites applications for one PhD and one Postdoc fellowship positions to develop advanced micro-nano-bio systems for fast sepsis diagnosis.

Background
The candidates will work for two projects, the SMARTDIAGNOS project (www.smartdiagnos.eu) and the VIVALDI project (www.vivaldi-ia.eu), which are both EU project under Horizon 2020 framework program which involves ten partners from five European countries. 

In these two projects, we aim at advancing sepsis and bacterial infection diagnosis by developing new diagnostic tools based on a number of cutting-edge micro-nano-bio and bio-photonic technologies. Sepsis and bacterial infection are big public health issues not only in EU but also worldwide because of its high incidence, mortality and economic cost. Sepsis diagnosis remains one of the greatest clinical challenges in critical care. The intended devices will enable fast and accurate identification of sepsis-related pathogens as well as their antibiotic resistance profiles, so that effective antimicrobial therapy can be initiated. Numerous steps, including sample preparation, DNA amplification and optical detection, will be integrated into single plastic cartridge and inserted in an instrument for an automatic assay, which will greatly simplify the current clinical analysis procedures.

Responsibilities and tasks
The main task of the position is to cover physical aspects of the device development, including the chip, the setup and the readout. The work includes: (1) design, fabrication and testing of injection molded plastic chips with micro-optical structures; (2) construction and testing of a setup with temperature control, microfluidic handling and optical readout; (3) simulation of microfluidic system, (4) automation of setup and data analysis; (5) collaboration with other partners on system integration and evaluation using biological samples.

Qualifications
The successful applicant for the Position should have a background (MSc/PhD degree or equivalent) in Applied Physics, Mechanics, Chemistry, Engineering, or related disciplines, with a strong background in micro and nanofabrication, optical detection, or system design and setup. Experience with microfluidics, simulation, injection molding, and/or construction, application, automation of lab-on-a-chip systems, or molecular biological methods like PCR will be considered an advantage. The candidate should be self-driven, and independent, show prior research productivity, excellent collaboration and communication skills, interest in working in an interdisciplinary research environment, and a strong motivation to succeed within a competitive research field as well as have a strong interest to work together with biologists and be part of a multidisciplinary team. The candidate will have a high motivation for research, evidence of solid written and oral communication skills.

Assessment
The assessment of the applicants will be made by an assessment committee chaired by Assoc. Prof. Anders Wolff. All applications will be reviewed to generate a short list of candidates. Potential candidates will be contacted for interview.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. DTU Nanotech offers state-of-the-art laboratory facilities for all parts of the project.

Salary and appointment terms
The appointment of the Postdoc position is based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union. The period of employment is 2 years. The start date of the position is as soon as possible.

The position will be based at the DTU Lyngby Campus, Denmark.

Further information 
Further information may be obtained from Anders Wolff (+45) 2245 0209, ander.wolff@nanotech.dtu.dk.

You can read more about DTU Nanotech on www.nanotech.dtu.dk.   

Application
Please submit your online application no later than 12 November 2018 (local time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include: 

  • Cover letter stating your specific interest, motivation and qualifications for the project.
  • Curriculum vitae including relevant information on previous employment, research training, experience and competencies, teaching experience, scientific publications, conference presentations and list of personal references.
  • Authorized copies of BSc, MSc, and PhD diplomas, and transcript of grades (an official translation into English).

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

DTU Nanotech - the Department of Micro- and Nanotechnology - is situated in the northern part of Copenhagen. DTU Nanotech is a centre of excellence in micro- and nanotechnology utilising sciences across the traditional boundaries of technology, thereby enabling innovative solutions for the benefit of society. DTU Nanotech has approx. 270 staff members. With 40 % international employees, the department constitutes an international environment.

DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government and public agencies.