Timo Hagemann

Timo Hagemann

PhD student

Department of Chemical and Biochemical Engineering


Technical University of Denmark

Søltofts Plads

Building 227, room 201

2800 Kgs. Lyngby

Request a vCard via e-mail.



Keywords Aspergillus niger, fermentation, morphology

Topic of thesis: Particle size investigation of Aspergillus niger pelleting behavior: causes and consequences for industrial fermentation
Starting date: November 2013
Background: M.Sc. equivalent (German “Diplom”) in Biotechnology, Technische Universität Braunschweig, Germany
Supervisors: Krist V. Gernaey, Ulrich Krühne, Stuart M. Stocks

The aim of this project is to track the Aspergillus niger biomass behaviour, beginning with spores and up to fully mature biomass. With manipulations of the fungus’ (fermentation) environment in terms of ion strength, pH value and mechanical power input by agitation as well as aeration and back pressure, it is intended to create specific biomass configurations – pelletous, mycelial and states between. Ideally, a model can predict the broth’s rheology in order to keep the OTR in the fermentation at the desired/highest possible level.

An outstanding trait of this project is the tight collaboration with Novozymes which enables knowledge fusion with industrial data. Ideally, the question of how important the morphology is for productivity in an industrial strain can be answered.