PhD Project in Photonics Technologies for Treatment & Diagnostics of Alzheimer´s and Dementia

DTU Fotonik
Tuesday 06 Nov 18

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Apply no later than 20 November 2018
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DTU Fotonik works with all areas of photonic engineering and the Department is now seeking to employ a PhD student to do research within new light sources for treatment & diagnostics of Alzheimer´s and dementia.

Description of the PhD project
Alzheimer´s and dementia are brain pathologies affecting language, memory, vision, motion, and mood. The increasing number of people living with dementia is already creating immense challenges for the global health and social systems. Alzheimer’s cannot be cured, but its progression can be slowed down and cognition partly restored. This PhD project will focus on the development of novel LED light source technology for early treatment of Alzheimer's and dementia diseases. A PhD student will test and validate the LED system. As part of the development of LED system, spatiotemporal, and dopaminergic retinal responses to flickering masked stimuli will be investigated in order to fully understand the underlying mechanisms for both visual and non-visual
photoreceptors, for optimal light delivery to the retina. The work includes design of LED architecture, principles for light flickering, color mixing for optimization of visual performance and color rendering, beam shaping and holographic diffusors for uniform high-quality light distribution. The research aims are to reestablish the neuron oscillatory activity for people with Alzheimer’s and to reduce beta amyloid plaque production using LED technology. Functional magnetic resonance imaging (FMRI) and PET imaging will be carried out in collaboration with medical doctors.

Responsibilities and tasks

  • Experimental work in an electro-optic laboratory.
  • Computational work on novel LED optic systems.
  • Dissemination of results through scientific publications, patents and conference presentations.
  • Supervision of MSc or BSc students.
  • The PhD study also comprises courses equivalent to 30 ECTS credits and an international secondment of 3-6 months duration.
Qualifications
Candidates should have a two-year master's degree (120 ECTS points) in engineering/Physics or a similar degree with an academic level equivalent to the MSc degree in engineering/Physics.

The candidate should possess most of the following:
  • Ability to work independently, to plan and carry out complicated research tasks, and also to be a part of the large research team.
  • Well-organized, efficient, result-oriented, have excellent record keeping abilities.
  • Team spirit and excellent collaboration skills
  • Computer proficiency. Ideally proficient in python.
  • Experience in development of electro-optics.
  • Strong analytical skills and excellent judgment ability.
  • Excellent communication skills, fluent written and oral English.
Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide.

Assessment
The assessment of the applicants will be made by Prof. Paul Michael Petersen, pape@fotonik.dtu.dk

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

The period of employment is 3 years.

Further information
For further information, please contact Prof. Paul Michael Petersen, pape@fotonik.dtu.dk

You can read more about DTU Fotonik on www.fotonik.dtu.dk

Please do not send applications to this e-mail address, instead apply online as described below.

Application
Please submit your online application no later than 20 November 2018.

Applications must be submitted as one pdf file containing all materials to be given consideration. To apply, please open the link "Apply online," fill in the online application form, and attach all your materials in English in one pdf file. The file must include:
  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and  Excel spreadsheet here
Candidates may apply prior to obtaining their MSc degree, but cannot begin before having received it.

All interested candidates irrespective of age, gender, race, disability, religion, or ethnic background are encouraged to apply.

DTU Fotonik has 210 employees with competences in optics and is one of the largest centers in the world based solely on research in photonics. Research is performed within optical sensors, lasers, LEDs, photovoltaics, ultra-high speed optical transmission systems, bio-photonics, nano-optics and quantum photonics.

DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government and public agencies.