PhD scholarship in Nano-Bio Science

DTU Food
Tuesday 03 Jul 18

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Apply no later than 12 August 2018
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The National Food Institute (DTU FOOD) at the Technical University of Denmark (DTU) seeks a candidate for a PhD Scholarship in Nano-Bio Science as soon as possible.

The PhD project will be hosted at the DTU FOOD and conducted in a close collaboration with the National Research Centre for the Working Environment (NRCWE). The project will be partially funded by the EU H2020 project PATROLS and conducted to support a newly established OECD project on the topic  Both groups are at the very forefront of international research in their respective fields and will provide a strong platform for the successful execution of the project. The NanoBio Science research group has a dynamic staff with high international visibility, many research collaborations with leading international universities and industry partners and the group has a successful track record of national and international research projects.

Information on solubility and dissolution rates is essential for assessing the potential mechanistic actions of manufactured nanomaterials (NM) and potential risks for human health. There is currently no internationally approved method for solubility and dissolution testing of NMs in biologically relevant media. This project aims to further develop, validate and apply different approaches for testing and quantifying the solubility and dissolution rate as well as caustic and redox activity of NMs in water and synthetic lung-lining-, phagolysosomal- and gastrointestinal fluids. The results will be used for modelling purposes to estimate the NM biodurability and transformation and fate in organisms.

Responsibilities and tasks
Your work will include performance of coupled solubility and reactivity testing for a variety of nanomaterials in a batch reactor system considering different media, test conditions, and the development of methods for quantification of the dissolved fraction, including those of carbon-based materials. Quantification includes ultrafiltration followed by quantification with inductively coupled plasma-mass spectrometry (ICP-MS) or in situ measurements. Additional techniques like asymmetric flow field-flow fractionation and size exclusion chromatography coupled to ICP-MS will be developed and applied to quantify the amount of molecular-bound species and understand potential interactions with medium constituents, including proteins.
As part of the Danish PhD program, you will follow a number of Ph.D. courses as well as take part in teaching.

Qualifications
You should have a master´s degree in engineering, chemistry or a similar degree with an academic level equivalent to the master´s degree in engineering/chemistry.

You should:

- have a background in inorganic chemistry / analytical chemistry, mineralogy or material science
- have  an excellent educational record
- have excellent communication skills in English (oral and written)
- be able to work independently but also in an interdisciplinary international team

Experience with nanoparticle characterization and ICP-MS is desirable. Knowledge about in vitro, in vivo or human toxicology will be considered an added value, but is not a requirement.

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from:
Katrin Loeschner (DTU): kals@food.dtu.dk; +45 35887029.
Keld Alstrup Jensen (NRCW) : KAJ@nfa.dk; +45 3916 5302.

You can read more about DTU Food at www.food.dtu.dk and http://www.arbejdsmiljoforskning.dk/en

Application
Please submit your online application no later than 12 August 2018.

Applications must be submitted as one pdf file containing all materials to be given consideration. To apply, please open the link "Apply online," fill in the online application form, and attach all your materials in English in one pdf file. The file must include:

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)

Candidates may apply prior to obtaining their master's degree, but cannot begin before having received it.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

DTU Food (The National Food Institute, Technical University of Denmark) works within six technical focus areas: Biotechnology, nutrition, food quality, food safety, food technology and environment & human health. Activities cover a wide range of food products throughout the entire food chain from farm to table, comprising both research activities and research-based consulting and teaching.

DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government and public agencies.