Cyclotron and Radionuclide Production Engineer within Biomedical Radiochemistry

DTU Nutech
Friday 19 Oct 18

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Applications are invited from enthusiastic and talented individuals for a position as Isotope Production Engineer for biomedical research at the Hevesy Laboratory at DTU Nutech (Risø Campus), Denmark.

Job description
As a cyclotron isotope expert, you will primarily be part of the research program at the Hevesy Laboratory. You will join the effort to investigate and develop new groundbreaking applications for radionuclides, especially radiometals. At the Hevesy Laboratory, radiochemical methodology, tracer and targeting systems are developed, synthesized and radiolabeled from ground. Through our broad national and international network, systems are subject to tests in animal models with the ultimate target of translation to humans.

Within this framework, your primary function will be the development, production and radiochemical work in the field of experimental radionuclides. Currently, these include Cu-64, manganese-52m, zirconium-89, lanthanum-135, erbium-165 and titanium-45, with general emphasis on radiometal production. New radionuclides will be introduced as they become relevant, and you are expected to take a major role in developing methods within production and purification. For the acquisition of these radionuclides into radiopharmaceutical drug delivery systems, you will assist other scientists working on similar areas.

Responsibilities
Your main responsibilities will be: 

  • Cyclotron production and radiochemical purification of experimental radionuclides
  • Support larger project frameworks focused on the development of radiopharmaceuticals
  • Operate as a resident cyclotron expert user
  • Ad-Hoc cyclotron experimental and technical support
  • Production of novel and hard-to-get isotopes at foreign reactors and high energy accelerators

You will contribute to the general strategy of the group and the design of new projects.

The candidate
The candidate must have an MSc degree or PhD degree in scientific technical engineering, physics, chemistry or related disciplines. In the assessment of the candidates, consideration will be given to: 

  • Experience with cyclotrons (theoretical and practical)
  • Experience with nuclear and radiochemistry
  • Knowledge on nuclear physics
  • Experience with the maintenance and manipulation of complex machinery
  • Theoretical knowledge of human physiology  

About the Laboratory
The Hevesy Laboratory is a radiochemical and radiopharmaceutical division within the Center for Nuclear Technologies (DTU Nutech), with about 50 employees. The laboratory has a 16.5 MeV cyclotron equipped with a beam line for in-house production of radioisotopes, both for PET scans (18F, 64Cu, 89Zr, 52Mn) and internal radiotherapy. These radioisotopes applies in radioactive pharmaceuticals. 

The laboratory has chemistry and biology research laboratories and clean rooms, which feature state-of-the-art equipment for working with radioisotopes. Our in-house GMP team produces radiopharmaceuticals for diagnostics and therapy, which are supplied to local hospitals and to external collaborators. The division also features a radioecology research section.

At present, the research group in radiopharmaceuticals at the Hevesy laboratory comprise a young and dynamic multidisciplinary team, focusing on the development of new radioactive pharmaceuticals for diagnostics and therapy. Our research is extensively interdisciplinary and multi-sited, featuring various collaborates both nationally and internationally. Several of these will be involved in this project. Communication in the research group is done in English.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed with the relevant union. The position is permanent and full-time. The starting date may be subject to a mutual agreement.

The primary place of work is The Hevesy Laboratory, DTU Risø Campus in Roskilde, Denmark.

Further information
Do not hesitate to contact Professor Mikael Jensen by e-mail or phone for questions and further details, kmje@dtu.dk, +45 2625 5890.

Please do not submit your application through e-mail (follow the instructions below).

Application
The application deadline is the 1 December 2018 (local time). Please open the link "apply for this job online" and fill in the application form and attach the following documents (all in English): 

  • Motivated application/cover letter (max 1 page)
  • Curriculum Vitae
  • Diploma (MSc/PhD – an official translation into English)
  • Degree certificates (if not yet completed, a statement from the university or supervisor(s) may suffice)
  • List of publications if relevant, including a brief description of how you contributed. Please include submissions and papers close to submission (we may ask to see these)
  • Copy of your academic grade transcripts (master’s and bachelor’s degrees), including an official description of how to convert the grades to the European Union (ECTS) or United States (ABC) grading systems

All interested candidates irrespective of age, gender, race, nationality, religion or ethnic background are encouraged to apply.

DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government and public agencies.