Kira Astakhova

Kira Astakhova

Associate Professor

DTU CHEMISTRY
Department of Chemistry

Kemi: Faculty

Technical University of Denmark

Kemitorvet

Building 206, room 118

2800 Kgs. Lyngby

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2018
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Autoantibody Profiling in Lupus Patients using Synthetic Nucleic Acids

Klecka, Martin ; Thybo, Christina ; Macaubas, Claudia ; Solov'yov, Ilia ; Simard, Julia ; Balboni, Imelda Maria ; Fox, Emily ; Voss, Anne ; Mellins, Elizabeth D ; Astakhova, Kira
in: Scientific Reports, vol: 8

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1038/s41598-018-23910-5

 

"Clicking" Gene Therapeutics: A Successful Union of Chemistry and Biomedicine for New Solutions

Astakhova, Kira ; Ray, Roslyn ; Taskova, Maria ; Uhd, Jesper ; Carstens, Annika ; Morris, Kevin
in: Molecular Pharmaceutics, vol: 15, issue: 8, pages: 2892-2899

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1021/acs.molpharmaceut.7b00765

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Detection of autoimmune antibodies in localized scleroderma by synthetic oligonucleotide antigens

Samuelsen, Simone ; Jørgensen, Christian Damsgaard ; Mellins, Elizabeth D ; Torok, Kathryn S ; Astakhova, Kira
in: P L o S One, vol: 13, issue: 4

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1371/journal.pone.0195381

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Dihydropyridine Fluorophores Allow for Specific Detection of Human Antibodies in Serum

Domljanovic, Ivana ; Rexen Ulven, Elisabeth ; Ulven, Trond ; Thomsen, Rasmus P. ; Okholm, Anders H. ; Kjems, Jørgen ; Voss, Anne ; Taskova, Maria ; Astakhova, Kira
in: ACS Omega, vol: 3, issue: 7, pages: 7580-7586

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1021/acsomega.8b00424

 

Improving the Design of Synthetic Oligonucleotide Probes by Fluorescence Melting Assay

Furlan, Ilaria ; Domljanovic, Ivana ; Uhd, Jesper ; Astakhova, Kira
in: Chembiochem

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2018     |    DOI: https://doi.org/10.1002/cbic.201800511

 

Modulation of Ldlr and Cholesterol by Transcriptional Silencing of the Long Non-Coding Rna Bm450697

Ray, Roslyn M. ; Hansen, Anders H. ; Taskova, Maria ; Astakhova, Kira ; Morris, Kevin V.
in: Molecular Therapy, vol: 26, issue: 5, pages: 39-39
Presented at:
21st Annual Meeting of the American Society of Gene and Cell Therapy

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1016/j.ymthe.2018.05.001

 

Studies of impending oligonucleotide therapeutics in simulated biofluids

Domljanovic, Ivana ; Hansen, Anders Højgaard ; Hansen, Lykke Haastrup ; Klitgaard, Janne Kudsk ; Taskova, Maria ; Astakhova, Kira
in: Nucleic Acid Therapeutics, vol: 28, issue: 6, pages: 348-356

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1089/nat.2017.0704

2017
 

2'-O-Me RNA probes modified with pyrene fluorophores: Attachment point matters

Astakhova, Kira ; Korshun, V.
in: Tetrahedron, vol: 73, pages: 3220-3230

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017

 

Amplification-free liquid biopsy by fluorescence approach

Uhd, J. ; Taskova, M. ; Okholm, A. ; Astakhova, Kira
part of: Techconnect 2017, Proceedings, 2017

Type: Article in proceedings (Peer reviewed)

Status: Published     |    Year: 2017

 

Antisense Oligonucleotides Internally Labeled with Peptides Show Improved Target Recognition and Stability to Enzymatic Degradation

Taskova, Maria ; Madsen, Charlotte S. ; Jensen, Knud Jørgen ; Hansen, Lykke Haastrup ; Vester, Birte ; Astakhova, Kira
in: Bioconjugate Chemistry, vol: 28, issue: 3, pages: 768-774

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1021/acs.bioconjchem.6b00567