Jens Nielsen

Jens Nielsen

Scientific Director

DTU BIOSUSTAIN
Novo Nordisk Foundation Center for Biosustainability

CFB-S-Yeast Cell Factories

Danmarks Tekniske Universitet

Kemitorvet

2800 Kgs. Lyngby

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2018
 

DCEO Biotechnology: Tools To Design, Construct, Evaluate, and Optimize the Metabolic Pathway for Biosynthesis of Chemicals

Chen, Xiulai ; Gao, Cong ; Guo, Liang ; Hu, Guipeng ; Luo, Qiuling ; Liu, Jia ; Nielsen, Jens ; Chen, Jian ; Liu, Liming
in journal: Chemical Reviews (ISSN: 0009-2665) (DOI: http://dx.doi.org/10.1021/acs.chemrev.6b00804), vol: 118, issue: 1, pages: 4-72, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1021/acs.chemrev.6b00804

 

Multiplexed CRISPR/Cas9 Genome Editing and Gene Regulation Using Csy4 in Saccharomyces cerevisiae

Ferreira, Raphael ; Skrekas, Christos ; Nielsen, Jens ; David, Florian
in journal: A C S Synthetic Biology (ISSN: 2161-5063) (DOI: http://dx.doi.org/10.1021/acssynbio.7b00259), vol: 7, issue: 1, pages: 10-15, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1021/acssynbio.7b00259

  PDF

Expression of cocoa genes in Saccharomyces cerevisiae improves cocoa butter production

Wei, Yongjun ; Bergenholm, David ; Gossing, Michael ; Siewers, Verena ; Nielsen, Jens
in journal: Microbial Cell Factories (ISSN: 1475-2859) (DOI: http://dx.doi.org/10.1186/s12934-018-0866-2), vol: 17, issue: 1, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1186/s12934-018-0866-2

  PDF

Redirection of lipid flux toward phospholipids in yeast increases fatty acid turnover and secretion

Ferreira, Raphael ; Teixeiraa, Paulo Goncalves ; Siewers, Verena ; Nielsen, Jens
in journal: Proceedings of the National Academy of Sciences of the United States of America (ISSN: 0027-8424) (DOI: http://dx.doi.org/10.1073/pnas.1715282115), vol: 115, issue: 6, pages: 1262-1267, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1073/pnas.1715282115

 

Modulation of saturation and chain length of fatty acids in Saccharomyces cerevisiae for production of cocoa butter-like lipids

Bergenholm, David ; Gossing, Michael ; Wei, Yongjun ; Siewers, Verena ; Nielsen, Jens
in journal: Biotechnology and Bioengineering (ISSN: 0006-3592) (DOI: http://dx.doi.org/10.1002/bit.26518), vol: 115, issue: 4, pages: 932-942, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1002/bit.26518

  PDF

Metabolic engineering of Saccharomyces cerevisiae for overproduction of triacylglycerols

Ferreira, Raphael ; Teixeira, Paulo Goncalves ; Gossing, Michael ; David, Florian ; Siewers, Verena ; Nielsen, Jens
in journal: Metabolic Engineering Communications (ISSN: 2214-0301) (DOI: http://dx.doi.org/10.1016/j.meteno.2018.01.002), vol: 6, pages: 22-27, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1016/j.meteno.2018.01.002

  PDF

Advancing biotechnology with CRISPR/Cas9: recent applications and patent landscape

Ferreira, Raphael ; David, Florian ; Nielsen, Jens
in journal: Journal of Industrial Microbiology and Biotechnology (ISSN: 1367-5435) (DOI: http://dx.doi.org/10.1007/s10295-017-2000-6), pages: 1-14, 2018

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    År: 2018     |    DOI: http://dx.doi.org/10.1007/s10295-017-2000-6

 

Engineering 1-Alkene Biosynthesis and Secretion by Dynamic Regulation in Yeast

Zhou, Yongjin J. ; Hu, Yating ; Zhu, Zhiwei ; Siewers, Verena ; Nielsen, Jens
in journal: A C S Synthetic Biology (ISSN: 2161-5063) (DOI: http://dx.doi.org/10.1021/acssynbio.7b00338), vol: 7, issue: 2, pages: 584-590, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1021/acssynbio.7b00338

  PDF

Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast

Bao, Jichen ; Huang, Mingtao ; Petranovic, Dina ; Nielsen, Jens
in journal: A M B Express (ISSN: 2191-0855) (DOI: http://dx.doi.org/10.1186/s13568-018-0571-x), vol: 8, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1186/s13568-018-0571-x

 

Metabolite secretion in microorganisms: the theory of metabolic overflow put to the test

Pinu, Farhana R. ; Granucci, Ninna ; Daniell, James ; Han, Ting-Li ; Carneiro, Sonia ; Rocha, Isabel ; Nielsen, Jens ; Villas-Boas, Silas G.
in journal: Metabolomics (ISSN: 1573-3882) (DOI: http://dx.doi.org/10.1007/s11306-018-1339-7), vol: 14, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1007/s11306-018-1339-7