Zoltan Imre Szallasi

Zoltan Imre Szallasi

Professor

DTU BIOINFORMATIK
Institut for Bio- og Sundhedsinformatik

Cancer Genomics
DTU Bioinformatics Employees

Danmarks Tekniske Universitet

Kemitorvet

Bygning 208, rum 010

2800 Kgs. Lyngby

Tlf.
Tlf.
Fax 45 93 15 85
E-mail zoltan@bioinformatics.dtu.dk
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Publikationer
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2017
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Fast and accurate mutation detection in whole genome sequences of multiple isogenic samples with IsoMut

Pipek, Orsolya ; Ribli, Dezső ; Molnar, Janos ; Poti, Adam ; Krzystanek, Marcin ; Bodor, András ; Tusnady, Gabor E. ; Szallasi, Zoltan Imre ; Csabai, Istvan ; Szüts, D.
in journal: B M C Bioinformatics (ISSN: 1471-2105) (DOI: http://dx.doi.org/10.1186/s12859-017-1492-4), vol: 18, issue: 1, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1186/s12859-017-1492-4

 

Evaluating the significance of density, localization, and PD-1/PD-L1 immunopositivity of mononuclear cells in the clinical course of lung adenocarcinoma patients with brain metastasis

Téglási, Vanda ; Reiniger, Lilla ; Fabian, Katalin ; Pipek, Orsolya ; Csala, Irén ; Bagó, Attila G. ; Várallyai, Péter ; Vízkeleti, Laura ; Rojkó, Lívia ; Tímár, József ; Dome, Balazs ; Szallasi, Zoltan Imre ; Swanton, Charles ; Moldvay, Judit
in journal: Neuro-Oncology (ISSN: 1522-8517) (DOI: http://dx.doi.org/10.1093/neuonc/now309), 2017

Type: Journal article (Peer reviewed)

Status: E-pub ahead of print     |    År: 2017     |    DOI: http://dx.doi.org/10.1093/neuonc/now309

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Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions

Zamborszky, J. ; Szikriszt, B. ; Gervai, J. Z. ; Pipek, O. ; Poti, A. ; Krzystanek, Marcin ; Ribli, D. ; Szalai-Gindl, J. M. ; Csabai, I. ; Szallasi, Zoltan Imre ; Swanton, C. ; Richardson, A L ; Szuets, D.
in journal: Oncogene (ISSN: 0950-9232) (DOI: http://dx.doi.org/10.1038/onc.2016.243), vol: 36, issue: 6, pages: 746-755, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1038/onc.2016.243

 

MuPeXI: prediction of neo-epitopes from tumor sequencing data

Bjerregaard, Anne-Mette ; Nielsen, Morten ; Hadrup, Sine Reker ; Szallasi, Zoltan Imre ; Eklund, Aron Charles
in journal: Cancer Immunology, Immunotherapy (ISSN: 0340-7004) (DOI: http://dx.doi.org/10.1007/s00262-017-2001-3), 2017

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    År: 2017     |    DOI: http://dx.doi.org/10.1007/s00262-017-2001-3

 

Tracking the Evolution of Non-Small-Cell Lung Cancer

Jamal-Hanjani, Mariam ; Wilson, Gareth A. ; McGranahan, Nicholas ; Birkbak, Nicolai Juul ; Watkins, Thomas B K ; Veeriah, Selvaraju ; Shafi, Seema ; Johnson, Diana H ; Mitter, Richard ; Rosenthal, Rachel ; Salm, Max ; Horswell, Stuart ; Escudero, Mickael ; Matthews, Nik ; Rowan, Andrew ; Chambers, Tim ; Moore, David A ; Turajlic, Samra ; Xu, Hang ; Lee, Siow-Ming ; Forster, Martin D ; Ahmad, Tanya ; Hiley, Crispin T ; Abbosh, Christopher ; Falzon, Mary ; Borg, Elaine ; Marafioti, Teresa ; Lawrence, David ; Hayward, Martin ; Kolvekar, Shyam ; Panagiotopoulos, Nikolaos ; Janes, Sam M ; Thakrar, Ricky ; Ahmed, Asia ; Blackhall, Fiona ; Summers, Yvonne ; Shah, Rajesh ; Joseph, Leena ; Quinn, Anne M ; Crosbie, Phil A ; Naidu, Babu ; Middleton, Gary ; Langman, Gerald ; Trotter, Simon ; Nicolson, Marianne ; Remmen, Hardy ; Kerr, Keith ; Chetty, Mahendran ; Gomersall, Lesley ; Fennell, Dean A ; Nakas, Apostolos ; Rathinam, Sridhar ; Anand, Girija ; Khan, Sajid ; Russell, Peter ; Ezhil, Veni ; Ismail, Babikir ; Irvin-Sellers, Melanie ; Prakash, Vineet ; Lester, Jason F ; Kornaszewska, Malgorzata ; Attanoos, Richard ; Adams, Haydn ; Davies, Helen ; Dentro, Stefan ; Taniere, Philippe ; O'Sullivan, Brendan ; Lowe, Helen L ; Hartley, John A ; Iles, Natasha ; Bell, Harriet ; Ngai, Yenting ; Shaw, Jacqui A. ; Herrero, Javier ; Szallasi, Zoltan Imre ; Schwarz, Roland F. ; Stewart, Aengus ; Quezada, Sergio A. ; Le Quesne, John ; Van Loo, Peter ; Dive, Caroline ; Hackshaw, Allan ; Swanton, Charles
in journal: New England Journal of Medicine (ISSN: 0028-4793) (DOI: http://dx.doi.org/10.1056/NEJMoa1616288), 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1056/NEJMoa1616288

 

Phylogenetic ctDNA analysis depicts early stage lung cancer evolution

Abbosh, Christopher ; Birkbak, Nicolai Juul ; Wilson, Gareth A. ; Jamal-Hanjani, Mariam ; Constantin, Tudor ; Salari, Raheleh ; Quesne, John Le ; Moore, David A. ; Veeriah, Selvaraju ; Rosenthal, Rachel ; Marafioti, Teresa ; Kirkizlar, Eser ; Watkins, Thomas B. K. ; McGranahan, Nicholas ; Ward, Sophia ; Martinson, Luke ; Riley, Joan ; Fraioli, Francesco ; Bakir, Maise Al ; Grönroos, Eva ; Zambrana, Francisco ; Endozo, Raymondo ; Bi, Wenya Linda ; Fennessy, Fiona M. ; Sponer, Nicole ; Johnson, Diana H. ; Laycock, Joanne ; Shafi, Seema ; Czyzewska-Khan, Justyna ; Rowan, Andrew ; Chambers, Tim ; Matthews, Nik ; Turajlic, Samra ; Hiley, Crispin T. ; Lee, Siow-Ming ; Forster, Martin D. ; Ahmad, Tanya ; Falzon, Mary ; Borg, Elaine ; Lawrence, David ; Hayward, Martin ; Kolvekar, Shyam ; Panagiotopoulos, Nikolaos ; Janes, Sam M. ; Thakrar, Ricky ; Ahmed, Asia ; Blackhall, Fiona ; Summers, Yvonne ; Hafez, Dina ; Naik, Ashwini ; Ganguly, Apratim ; Kareht, Stephanie ; Shah, Rajesh ; Joseph, Leena ; Quinn, Anne Marie ; Crosbie, Phil A. ; Naidu, Babu ; Middleton, Gary ; Langman, Gerald ; Trotter, Simon ; Nicolson, Marianne ; Remmen, Hardy ; Kerr, Keith ; Chetty, Mahendran ; Gomersall, Lesley ; Fennell, Dean A. ; Nakas, Apostolos ; Rathinam, Sridhar ; Anand, Girija ; Khan, Sajid ; Russell, Peter ; Ezhil, Veni ; Ismail, Babikir ; Irvin-Sellers, Melanie ; Prakash, Vineet ; Lester, Jason F. ; Kornaszewska, Malgorzata ; Attanoos, Richard ; Adams, Haydn ; Davies, Helen ; Oukrif, Dahmane ; Akarca, Ayse U. ; Hartley, John A. ; Lowe, Helen L ; Lock, Sara ; Iles, Natasha ; Bell, Harriet ; Ngai, Yenting ; Elgar, Greg ; Szallasi, Zoltan Imre ; Schwarz, Roland F. ; Herrero, Javier ; Stewart, Aengus ; Quezada, Sergio A. ; Van Loo, Peter ; Dive, Caroline ; Lin, C. Jimmy ; Rabinowitz, Matthew ; Aerts, Hugo J.W.L. ; Hackshaw, Allan ; Shaw, Jacqui A. ; Zimmermann, Bernhard G. ; Swanton, Charles
in journal: Nature (ISSN: 0028-0836) (DOI: http://dx.doi.org/10.1038/nature22364), vol: 545, pages: 446-451, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1038/nature22364

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Quantification of within-sample genetic heterogeneity from SNP-array data

Martinez, Pierre ; Kimberley, Christopher ; Birkbak, Nicolai Juul ; Marquard, Andrea Marion ; Szallasi, Zoltan Imre ; A. Graham, Trevor
in journal: Scientific Reports (ISSN: 2045-2322) (DOI: http://dx.doi.org/10.1038/s41598-017-03496-0), vol: 7, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1038/s41598-017-03496-0

2016
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MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy

Neupane, Manish ; Clark, Allison P. ; Landini, Serena ; Birkbak, Nicolai Juul ; Eklund, Aron Charles ; Lim, Elgene ; Culhane, Aedin C. ; Barry, William T. ; Schumacher, Steven E. ; Beroukhim, Rameen ; Szallasi, Zoltan Imre ; Vidal, Marc ; Hill, David E. ; Silver, Daniel P.
in journal: Cancer Discovery (ISSN: 2159-8274) (DOI: http://dx.doi.org/10.1158/2159-8290.cd-15-0341), vol: 6, issue: 1, pages: 45-58, 2016

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: http://dx.doi.org/10.1158/2159-8290.cd-15-0341

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A robust prognostic gene expression signature for early stage lung adenocarcinoma

Krzystanek, Marcin ; Moldvay, Judit ; Szüts, David ; Szallasi, Zoltan Imre ; Eklund, Aron Charles
in journal: Biomarker Research (ISSN: 2050-7771) (DOI: http://dx.doi.org/10.1186/s40364-016-0058-3), vol: 4, issue: 4, 2016

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: http://dx.doi.org/10.1186/s40364-016-0058-3