Søren Brunak

Søren Brunak

Professor

DTU BIOINFORMATIK
Institut for Bio- og Sundhedsinformatik

Integrative Systems Biology
DTU Bioinformatics Employees

Danmarks Tekniske Universitet

Kemitorvet

Bygning 208, rum 016

2800 Kgs. Lyngby

Tlf.
Tlf.
Fax 45 93 15 85
E-mail brunak@bioinformatics.dtu.dk
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Publikationer
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2018
 

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

Molnos, Sophie ; Wahl, Simone ; Haid, Mark ; Eekhoff, E. Marelise W. ; Pool, René ; Floegel, Anna ; Deelen, Joris ; Much, Daniela ; Prehn, Cornelia ; Breier, Michaela ; Draisma, Harmen H. ; van Leeuwen, Nienke ; Simonis-Bik, Annemarie M.C. ; Jonsson, Anna Elisabet ; Willemsen, Gonneke ; Bernigau, Wolfgang ; Wang-Sattler, Rui ; Suhre, Karsten ; Peters, Annette ; Thorand, Barbara ; Herder, Christian ; Rathmann, Wolfgang ; Roden, Michael ; Gieger, Christian ; Kramer, Mark H.H. ; van Heemst, Diana ; Pedersen, Helle Krogh ; Gudmundsdottir, Valborg ; Schulze, Matthias B. ; Pischon, Tobias ; de Geus, Eco J.C. ; Boeing, Heiner ; Boomsma, Dorret I. ; Ziegler, Anette G. ; Slagboom, P. Eline ; Hummel, Sandra ; Beekman, Marian ; Grallert, Harald ; Brunak, Søren ; McCarthy, Mark I. ; Gupta, Ramneek ; Pearson, Ewan R. ; Adamski, Jerzy ; 'T Hart, Leen M.
in: Diabetologia (ISSN: 0012-186X), vol: 61, pages: 117-129, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1007/s00125-017-4436-7

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miRandola 2017: a curated knowledge base of non-invasive biomarkers

Russo, Francesco ; Di Bella, Sebastiano ; Vannini, Federica ; Berti, Gabriele ; Scoyni, Flavia ; Cook, Helen Victoria ; Santos, Alberto ; Nigita, Giovanni ; Bonnici, Vincenzo ; Laganà, Alessandro ; Geraci, Filippo ; Pulvirenti, Alfredo ; Giugno, Rosalba ; De Masi, Federico ; Belling, Kirstine González-Izarzugaza ; Jensen, Lars Juhl ; Brunak, Søren ; Pellegrini, Marco ; Ferro, Alfredo
in: Nucleic Acids Research (ISSN: 0305-1048), vol: 46, issue: D1, pages: D354-D359, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1093/nar/gkx854

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Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

Gudmundsdottir, Valborg ; Pedersen, Helle Krogh ; Allebrandt, Karla Viviani ; Brorsson, Caroline Anna ; van Leeuwen, Nienke ; Banasik, Karina ; Mahajan, Anubha ; Groves, Christopher J ; van de Bunt, Martijn ; Dawed, Adem Y ; Fritsche, Andreas ; Staiger, Harald ; Simonis-Bik, Annemarie M C ; Deelen, Joris ; Kramer, Mark H H ; Dietrich, Axel ; Hübschle, Thomas ; Willemsen, Gonneke ; Häring, Hans-Ulrich ; de Geus, Eco J C ; Boomsma, Dorret I ; Eekhoff, Elisabeth M W ; Ferrer, Jorge ; McCarthy, Mark I ; Pearson, Ewan R ; Gupta, Ramneek ; Brunak, Søren ; 't Hart, Leen M
in: P L o S One (ISSN: 1932-6203), vol: 13, issue: 1, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1371/journal.pone.0189886

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Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

Kristensen, David Møbjerg ; Desdoits-Lethimonier, Christèle ; Mackey, Abigail L ; Dalgaard, Marlene Danner ; De Masi, Federico ; Munkbøl, Cecilie Hurup ; Styrishave, Bjarne ; Antignac, Jean-Philippe ; Le Bizec, Bruno ; Platel, Christian ; Hay-Schmidt, Anders ; Jensen, Tina Kold ; Lesné, Laurianne ; Mazaud-Guittot, Séverine ; Kristiansen, Karsten ; Brunak, Søren ; Kjær, Michael ; Juul, Anders Christian ; Jégou, Bernard
in: Proceedings of the National Academy of Sciences of the United States of America (ISSN: 0027-8424), vol: 115, issue: 17, pages: E715-E724, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1073/pnas.1715035115

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Analysis of a gene panel for targeted sequencing of colorectal cancer samples

Jensen, Klaus Højgaard ; Gonzalez-Izarzugaza, Jose Maria ; Juncker, Agnieszka ; Borup Hansen, Rasmus ; Frøstrup Hansen, Torben ; Timshel, Pascal ; Blondal, Thorarinn ; Jensen, Thomas Skøt ; Rygaard-Hjalsted, Eske ; Mouritzen, Peter ; Thorsen, Michael ; Wernersson, Rasmus ; Nielsen, Henrik Bjørn ; Jakobsen, Anders ; Brunak, Søren ; Brandt Sørensen, Flemming
in: OncoTarget (ISSN: 1949-2553), vol: 9, issue: 10, pages: 9043-9060, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.18632/oncotarget.24138

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A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts

Westergaard, David ; Stærfeldt, Hans Henrik ; Tønsberg, Christian ; Jensen, Lars Juhl ; Brunak, Søren
in: P L o S Computational Biology (Online) (ISSN: 1553-7358), vol: 14, issue: 2, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1371/journal.pcbi.1005962

 

Accurate genotyping across variant classes and lengths using variant graphs

Sibbesen, Jonas Andreas ; Maretty, Lasse ; Jensen, Jacob Malte ; Petersen, Bent ; Liu, Siyang ; Villesen, Palle ; Skov, Laurits ; Belling, Kirstine González-Izarzugaza ; Theil Have, Christian ; Gonzalez-Izarzugaza, Jose Maria ; Grosjean, Marie ; Bork-Jensen, Jette ; Grove, Jakob ; Dam-Als, Thomas ; Huang, Shujia ; Chang, Yuqi ; Xu, Ruiqi ; Ye, Weijian ; Rao, Junhua ; Guo, Xiaosen ; Sun, Jihua ; Cao, Hongzhi ; Ye, Chen ; van Beusekom, Johan ; Espeseth, Thomas ; Flindt, Esben ; Friborg, Rune M. ; Halager, Anders Egerup ; Le Hellard, Stephanie ; Hultman, Christina M. ; Lescai, Francesco ; Li, Shengting ; Lund, Ole ; Løngren, Peter ; Mailund, Thomas ; Matey-Hernandez, María Luisa ; Mors, Ole ; Pedersen, Christian N. S. ; Sicheritz-Pontén, Thomas ; Sullivan, Patrick ; Qaswar Ali Shah, Syed ; Westergaard, David ; Yadav, Rachita ; Li, Ning ; Xu, Xun ; Hansen, Torben ; Krogh, Anders ; Bolund, Lars ; Sørensen, Thorkild I. A. ; Pedersen, Oluf ; Gupta, Ramneek ; Rasmussen, Simon ; Besenbacher, Søren ; Børglum, Anders D. ; Wang, Jun ; Eiberg, Hans ; Kristiansen, Karsten ; Brunak, Søren ; Schierup, Mikkel Heide
in: Nature Genetics (ISSN: 1061-4036), 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1038/s41588-018-0145-5

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Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios

Matey-Hernandez, María Luisa ; Maretty, Lasse ; Jensen, Jacob Malte ; Petersen, Bent ; Andreas Sibbesen, Jonas ; Liu, Siyang ; Villesen, Palle ; Skov, Laurits ; Belling, Kirstine González-Izarzugaza ; Theil Have, Christian ; Gonzalez-Izarzugaza, Jose Maria ; Grosjean, Marie ; Bork-Jensen, Jette ; Grove, Jakob ; Als, Thomas D. ; Huang, Shujia ; Chang, Yuqi ; Xu, Ruiqi ; Ye, Weijian ; Rao, Junhua ; Guo, Xiaosen ; Sun, Jihua ; Cao, Hongzhi ; Ye, Chen ; Beusekom, Johan v. ; Espeseth, Thomas ; Flindt, Esben N. ; Friborg, Rune M. ; Halager, Anders Egerup ; Le Hellard, Stephanie ; Hultman, Christina M. ; Lescai, Francesco ; Li, Shengting ; Lund, Ole ; Løngren, Peter ; Mailund, Thomas ; Mors, Ole ; Pedersen, Christian N. S. ; Sicheritz-Pontén, Thomas ; Sullivan, Patrick F. ; Qaswar Ali Shah, Syed ; Westergaard, David ; Yadav, Rachita ; Li, Ning ; Xu, Xun ; Hansen, Torben ; Krogh, Anders ; Bolund, Lars ; Sørensen, Thorkild I. A. ; Pedersen, Oluf ; Gupta, Ramneek ; Besenbacher, Søren ; Børglum, Anders D. ; Wang, Jun ; Eiberg, Hans ; Kristiansen, Karsten ; Brunak, Søren ; Schierup, Mikkel Heide
in: B M C Bioinformatics (ISSN: 1471-2105), vol: 19, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1186/s12859-018-2239-6

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The governance structure for data access in the DIRECT consortium: an innovative medicines initiative (IMI) project

Teare, Harriet J. A. ; De Masi, Federico ; Banasik, Karina ; Barnett, Anna ; Herrgard, Sanna ; Jablonka, Bernd ; Postma, Jacqueline W. M. ; McDonald, Timothy J. ; Forgie, Ian ; Chmura, Piotr Jaroslaw ; Rydzka, Emil K. ; Gupta, Ramneek ; Brunak, Søren ; Pearson, Ewan ; Kaye, Jane
in: Life Sciences, Society and Policy (ISSN: 2195-7819), vol: 14, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: http://dx.doi.org/10.1186/s40504-018-0083-0

2017
 

Combinatorial Drug Screening Identifies Ewing Sarcoma-specific Sensitivities

Radic-Sarikas, Branka ; Tsafou, Kalliopi P ; Emdal, Kristina B. ; Papamarkou, Theodore ; Huber, Kilian V. M. ; Mutz, Cornelia ; Toretsky, Jeffrey A ; Bennett, Keiryn L. ; Olsen, Jesper V. ; Brunak, Søren ; Kovar, Heinrich ; Superti-Furga, Giulio
in: Molecular Cancer Therapeutics (ISSN: 1535-7163), vol: 16, issue: 1, pages: 88-101, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: http://dx.doi.org/10.1158/1535-7163.MCT-16-0235