DTU Sundhedsteknologi
DTU Bioinformatik
Valborg Gudmundsdottir

Valborg Gudmundsdottir

Postdoc

Institut for Bio- og Sundhedsinformatik

Integrative Systems Biology
DTU Bioinformatics Employees

Danmarks Tekniske Universitet

Kemitorvet

Bygning 208, rum 019

2800 Kgs. Lyngby

Tlf.
Tlf.
Mobil
Fax 45 93 15 85
E-mail valborg@bioinformatics.dtu.dk
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Publikationer
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2018
 

A computational framework to integrate high-throughput '-omics' datasets for the identification of potential mechanistic links

Pedersen, Helle Krogh ; Forslund, Sofia K ; Gudmundsdottir, Valborg ; Petersen, Anders Østergaard ; Hildebrand, Falk ; Hyötyläinen, Tuulia ; Nielsen, Trine ; Hansen, Torben ; Bork, Peer ; Ehrlich, S Dusko ; Brunak, Søren ; Oresic, Matej ; Pedersen, Oluf ; Nielsen, Henrik Bjørn
in: Nature Protocols, vol: 13, pages: 2781-2800

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: https://doi.org/10.1038/s41596-018-0064-z

  PDF

Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

Gudmundsdottir, Valborg ; Pedersen, Helle Krogh ; Allebrandt, Karla Viviani ; Brorsson, Caroline Anna ; van Leeuwen, Nienke ; Banasik, Karina ; Mahajan, Anubha ; Groves, Christopher J ; van de Bunt, Martijn ; Dawed, Adem Y ; Fritsche, Andreas ; Staiger, Harald ; Simonis-Bik, Annemarie M C ; Deelen, Joris ; Kramer, Mark H H ; Dietrich, Axel ; Hübschle, Thomas ; Willemsen, Gonneke ; Häring, Hans-Ulrich ; de Geus, Eco J C ; Boomsma, Dorret I ; Eekhoff, Elisabeth M W ; Ferrer, Jorge ; McCarthy, Mark I ; Pearson, Ewan R ; Gupta, Ramneek ; Brunak, Søren ; 't Hart, Leen M
in: P L o S One, vol: 13, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: https://doi.org/10.1371/journal.pone.0189886

 

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

Molnos, Sophie ; Wahl, Simone ; Haid, Mark ; Eekhoff, E. Marelise W. ; Pool, René ; Floegel, Anna ; Deelen, Joris ; Much, Daniela ; Prehn, Cornelia ; Breier, Michaela ; Draisma, Harmen H. ; van Leeuwen, Nienke ; Simonis-Bik, Annemarie M.C. ; Jonsson, Anna Elisabet ; Willemsen, Gonneke ; Bernigau, Wolfgang ; Wang-Sattler, Rui ; Suhre, Karsten ; Peters, Annette ; Thorand, Barbara ; Herder, Christian ; Rathmann, Wolfgang ; Roden, Michael ; Gieger, Christian ; Kramer, Mark H.H. ; van Heemst, Diana ; Pedersen, Helle Krogh ; Gudmundsdottir, Valborg ; Schulze, Matthias B. ; Pischon, Tobias ; de Geus, Eco J.C. ; Boeing, Heiner ; Boomsma, Dorret I. ; Ziegler, Anette G. ; Slagboom, P. Eline ; Hummel, Sandra ; Beekman, Marian ; Grallert, Harald ; Brunak, Søren ; McCarthy, Mark I. ; Gupta, Ramneek ; Pearson, Ewan R. ; Adamski, Jerzy ; 'T Hart, Leen M.
in: Diabetologia, vol: 61, pages: 117-129

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: https://doi.org/10.1007/s00125-017-4436-7

2017
  PDF

Clustering on baseline clinical variables identifies subgroups of type 2 diabetes patients with different rate of progression over 18 months: a DIRECT study

Brorsson, Caroline Anna ; Pedersen, H. Krogh ; Gudmundsdottir, Valborg ; Mari, A. ; Kurbasic, A. ; Vinuela, A. ; Fernandez, J. ; Mahajan, A. ; Gupta, R. ; Dermitzakis, E. ; MacCarthy, M. ; Franks, P. ; Pearson, E. ; Brunak, Søren
in: Diabetologia, vol: 60, issue: Suppl. 1, pages: S117
Presented at:
53rd EASD Annual Meeting of the European Association for the Study of Diabetes

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    År: 2017

 

Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis

Crèvecoeur, Inne ; Gudmundsdottir, Valborg ; Vig, Saurabh ; Marques Câmara Sodré, Fernanda ; D'Hertog, Wannes ; Fierro, Ana Carolina ; Van Lommel, Leentje ; Gysemans, Conny ; Marchal, Kathleen ; Waelkens, Etienne ; Schuit, Frans ; Brunak, Søren ; Overbergh, Lut ; Mathieu, Chantal
in: Diabetologia, vol: 60, issue: 3, pages: 475-489

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: https://doi.org/10.1007/s00125-016-4191-1

  PDF

Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes

Pedersen, Helle Krogh ; Gudmundsdottir, Valborg ; Brunak, Søren
in: Frontiers in Genetics, vol: 8

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: https://doi.org/10.3389/fgene.2017.00043

2016
 

Human gut microbes impact host serum metabolome and insulin sensitivity

Pedersen, Helle Krogh ; Gudmundsdottir, Valborg ; Nielsen, Henrik Bjørn ; Hyotylainen, Tuulia ; Nielsen, Trine ; Jensen, Benjamin A. H. ; Forslund, Kristoffer ; Hildebrand, Falk ; Prifti, Edi ; Falony, Gwen ; Le Chatelier, Emmanuelle ; Levenez, Florence ; Dore, Joel ; Mattila, Ismo ; Plichta, Damian Rafal ; Poho, Paivi ; Hellgren, Lars ; Arumugam, Manimozhiyan ; Sunagawa, Shinichi ; Vieira-Silva, Sara ; Jørgensen, Torben ; Holm, Jacob Bak ; Trost, Kajetan ; Kristiansen, Karsten ; Pedersen, Susanne Brix ; Raes, Jeroen ; Wang, Jun ; Hansen, Torben ; Bork, Peer ; Brunak, Søren ; Oresic, Matej ; Ehrlich, S. Dusko ; Pedersen, Oluf
in: Nature, vol: 535, issue: 7612, pages: 376-381

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: https://doi.org/10.1038/nature18646

2015
 

A proteomic study of the regulatory role for STAT-1 in cytokine-induced beta-cell death

Rondas, Dieter ; Gudmundsdottir, Valborg ; D’Hertog, Wannes ; Crèvecoeur, Inne ; Waelkens, Etienne ; Brunak, Søren ; Mathieu, Chantal ; Overbergh, Lut
in: Proteomics - Clinical Applications, vol: 9, issue: 9-10, pages: 938-952

Type: Journal article (Peer reviewed)

Status: E-pub ahead of print     |    År: 2015     |    DOI: https://doi.org/10.1002/prca.201400124

 

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

Forslund, Kristoffer ; Hildebrand, Falk  ; Nielsen, Trine N. ; Falony, Gwen ; Le Chatelier, Emmanuelle ; Sunagawa, Shinichi ; Prifti, Edi ; Vieira-Silva, Sara ; Gudmundsdottir, Valborg ; Pedersen, Helle Krogh ; Arumugam, Manimozhiyan ; Kristiansen, Karsten ; Yvonne Voig, Anita ; Vestergaard, Henrik ; Hercog, Rajna ; Costea, Paul Igor ; Kultima, Jens Roat ; Li, Junhua ; Jørgensen, Torben ; Levenez, Florence ; Dore, Joël ; Nielsen, Henrik Bjørn ; Brunak, Søren ; Raes, Jeroen ; Hansen, Torben ; Wang, Jun ; Ehrlich, S. Dusko ; Bork, Peer ; Pedersen, Oluf
in: Nature, vol: 528, issue: 7581, pages: 262-266

Type: Letter (Peer reviewed)

Status: Published     |    År: 2015     |    DOI: https://doi.org/10.1038/nature15766