Postdoctoral Researcher in Next Generation Antibody Engineering

Friday 23 Oct 20

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The Section of Protein Science and Biotherapeutics at the Department of Biotechnology and Biomedicine has an opening for a 3-year position as postdoctoral researcher. The position will be available from December 2020 or soon thereafter.

The successful applicant will work within the young and rapidly growing research group ‘Biotherapeutic Glycoengineering and Immunology’ headed by Professor Steffen Goletz and is partially funded by a NNF grant with a special focus on innovation.

In our research group, we apply and develop advanced next generation antibody engineering and glycoengineering technologies to elucidate the role of glycosylations for the microbiome, disease and complex immunological networks and use these for identifying novel drug targets and generating novel drug candidates and therapeutic strategies. Our main therapeutic interest is within bacterial and viral gastrointestinal and lung diseases as well as a strong focus on immunooncology. Our focus lies within next generation antibody engineering with multimodal  antibody constructs, phage display technologies, molecular and cellular glycoengineering, and mammalian bioprocess engineering as well as glycoimmunology, microbiome glycoengineering, glycomic and glycomimetic display systems. We also have a strong focus on innovation and entrepreneurship.

Responsibilities and tasks
The newly recruited postdoctoral researcher will generate novel multimodal antibody constructs and platforms for studying the microbiota and develop new therapeutic approaches to infectious diseases.

The position will be collaboratively embedded in our strong multidisciplinary team in immunology, molecular and cellular glycoengineering, complex antibody engineering, cell factory and bioprocess engineering, proteomics and glycomics, as well as infectious diseases and cancer immunotherapy, and collaborate with national and international partners.

Qualifications
Applicants should hold a PhD in a life sciences discipline, have excellent communication skills and be extensively trained in antibody engineering, phage display, protein biochemistry and biophysical characterization, expression and purification of proteins, and microbiology.

Prior successful postdoctoral research and supervision of PhD students is not mandatory but would be highly advantageous, and knowledge of bispecific antibody, nanobody or fusionprotein technologies, a broad spectrum of immune-based assays and anti-infective diseases research would be strong assets. The ideal candidate would be also familiar with microbiota research.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union. 

You can read more about career paths at DTU here.

The position will be located at the DTU Lyngby campus in the recently established research building 225 hosting state-of-the-art laboratories for e.g. protein science and antibody engineering, phage display, microbiome research, immunology and cellular research, mammalian bioprocessing as well as the DTU Proteomics Core.

The position is for 3 years.

Further Information
Additional information may be obtained from Prof. Dr. Steffen Goletz, Vice Director of the Institute, sgoletz@dtu.dk

Application procedure
Please submit your online application no later than 27 November 2020 (Danish time).

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • Diploma (MSc/PhD)
  • List of publications

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,000 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. Our main campus is in Kgs. Lyngby north of Copenhagen and we have campuses in Roskilde and Ballerup and in Sisimiut in Greenland.