PhD scholarship in Super Resolution Ultrasound Imaging

Tuesday 14 Jan 20

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A 3-year PhD scholarship is available at the Center for Fast Ultrasound Imaging (CFU), Department of Health Technology from March 2020 sponsored by the European Research Council (ERC) and the Department of Health Technology at DTU. It is conducted in collaboration between CFU and the MEMS group at DTU Health Tech, the University of Copenhagen, and the Copenhagen University Hospital (Rigshospitalet) in the ERC Synergy Grant “3-D Super resolution Ultrasound Real time imaging of Erythrocytes” - SURE.

The SURE project develops and researches a new super resolution ultrasound imaging method capable of resolving 3-D capillary flow in the human body. The approach tracks the motion of the individual red blood cells (erythrocytes) in a three-dimensional volume for a full visualization of anatomy, flow, and perfusion. The approach can potentially yield a paradigm shift in the scientific study, diagnoses, and treatment of cancer, diabetes, and vascular diseases at the capillary level, as it enables the possibility of volumetrically visualizing capillary perfusion in real-time at frame rates above 20 Hz without injection of contrast agents.

Responsibilities and tasks
This PhD projects develops the imaging schemes for acquiring the data using row-column matrix arrays and isolating the targets, and for tracking and visualizing them in 2D and 3D. The project also includes performing a range of phantom and animal experiments to develop and refine the SURE algorithms. Animal experiments are conducted with medical doctors at the University of Copenhagen.

The research is conducted in a truly multi-disciplinary environment consisting of the 4 academic partners specializing in advanced ultrasound imaging, silicon CMUT probes, animal experiments, and clinical investigations, and the main purpose is to translate the SURE method from a research idea to the clinic.

The main task is to develop suitable ultrasound imaging schemes based on the previous work at CFU on synthetic aperture imaging with row-column matrix arrays and to make target isolation, tracking, and visualization. This is integrated in our SURE processing framework and tested on 3D printed soft-tissue phantoms. The scheme is then implemented on our research scanners for pre-clinical trials at the University of Copenhagen. The implementation will finally be clinically evaluated in human trials conducted together with the Department of Radiology at Rigshospitalet to reveal its efficacy.

Qualifications
Candidates should have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree. Experience with digital signal processing is desirable. Similarly, knowledge of medical imaging and acoustics will also be beneficial.

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years. 

You can read more about career paths at DTU here.

Further information
Further information is available at www.cfu.dtu.dk or from Professor Jørgen Arendt Jensen, tel: +45 4525 3924, e-mail: jaje@dtu.dk

Please do not send applications to this e-mail address, instead apply online as described below.

You can read more about Department of Health Technology on www.healthtech.dtu.dk and about CFU at www.cfu.dtu.dk/

Application
Please submit your online application no later than 21 February 2020 (23:59 local time)Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include: 

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)
Candidates may apply prior to obtaining their master's degree but cannot begin before having received it.

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products, which benefit people and create value for society. DTU Health Techs expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies.

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DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 11,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. Our main campus is in Kgs. Lyngby north of Copenhagen and we have campuses in Roskilde and Ballerup and in Sisimiut in Greenland.