PhD Scholarship in In-Situ NMR based Metabonomics of Microbial Secondary Metabolites

Thursday 12 Sep 19

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Apply no later than 20 October 2019
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We offer a PhD fellowship at the Department of Chemistry at the Technical University of Denmark. The PhD project is part of the Center for Microbial Secondary Metabolites, CeMiSt and will be executed at the NMR Center DTU under the supervision of Charlotte Held Gotfredsen.

 

CeMiSt is a Center of Excellence funded by the Danish National Research Foundation. The Center started 1st of January 2018 and will run for six years with an option for a four-year extension. The Center is based at the Technical University of Denmark and hosted by Department of Biotechnology and Biomedicine (DTU Bioengineering). Three DTU departments and 10 senior faculty participate in the Center and >10 PhD students and postdocs will be hired. The purpose of CeMiSt is to unravel the biological role of microbial secondary metabolites in natural microbiological communities. The Center is led by Professor Lone Gram.

 

We are seeking a candidate to study the secondary metabolite profile from microbial sources using mainly NMR spectroscopy as the analytical technology and metabonomics tools for data mining to track and extract data on the production and diversity of secondary metabolites. You will be involved in a fun, highly interdisciplinary PhD project on microbial natural products. You will engage with many other scientists within CeMiSt, which is a very productive scientific environment with strong international connections and also be part of the NMR Center DTU a large DTU Campus infrastructure.

 

Responsibilities and tasks

Your PhD project will contribute to our understanding of the role and occurrence of secondary metabolites on microbial interactions and evolution. You will explore the diversity of the secondary metabolites profiles and their dependence on the microbial community assembly from which they are obtained. In-situ NMR spectroscopy will be the main analytical technique used. Metabonomics and datamining with be important for the project and correlation with orthogonal genomic data will be an important part in collaborations within CeMiSt.

 

Qualifications
The successful candidate should have a Master’s degree in chemistry/engineering/mathematics with prior experience in computer science or NMR spectroscopy. Experience in metabonomics/metabolomics would be an advantage. However, a keen interest in applying analytical and computational tools to mine big data is important. Most importantly, the candidate should be highly motivated, able to work independently and should be confident in both written and spoken English. Expected starting date: December 2019.

 

Approval and Enrolment

The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide.

 

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

 

Salary and appointment terms

The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.

 

You can read more about career paths at DTU here.

 
Further information

Further questions about the project should be directed to Associate Professors Charlotte Held Gotfredsen (chg@kemi.dtu.dk) or Mikael Lenz Strube (milst@dtu.dk), or CeMiSt Center leader, Professor Lone Gram (gram@bio.dtu.dk).

 

You can read more about the Department of Chemistry at www.kemi.dtu.dk and about CeMiSt at www.cemist.dtu.dk

 

Please submit your online application no later than 20 October 2019.

 

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)

Candidates may apply prior to obtaining their master's degree, but cannot begin before having received it.

 

Applications and enclosures received after the deadline will not be considered.

 

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

 

DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent university collaborating globally with business, industry, government and public agencies.