Postdoc position within Mid-IR Hyperspectral Imaging of Bio Samples

Monday 04 Jan 21

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The Department of Photonics Engineering at the Technical University of Denmark (DTU) is seeking a highly motivated postdoctoral candidate for a postdoc position within the field of mid-IR upconversion imaging and spectroscopy. The aim of this ambitious project is to open a new field: “mid-infrared transmission spectroscopy of wet biological samples”. The successful candidate will challenge the prevailing idea, that MIR transmission spectroscopy is not technically feasible for fresh bio samples (in vitro). In order to challenge this paradigm, the candidate need to overcome the exorbitant strong mid-IR absorption from water in the sample, while keeping sample illumination at a safe to avoid sample damage.

The candidate will set up a novel MIR spectrometer in the 6-15 µm range with ultimate sensitivity approaching the single photon limit. The ispectrometer is specifically designed for mid-IR hyperspectral bio imaging. A hyperspectral bio image shows both chemical content and morphology analogous to human colour vision when analyzing a “spot” on the skin of an apple. This technique has already showed remarkable results and will possibly/eventually(!) replace a more than 100 years old, gold standard technique for biopsy screening, based on staining (e.g. H&E staining).

The Optical Sensor Technology has researched for more than 10 years into hyperspectral upconversion imaging and has an on-going activity on hyperspectral imaging of bio-samples. Therefor the candidate will have access to both supervision/sparring as well as fully equipped laboratory facilities.

Responsibilities and tasks
The potential candidates are expected to work in a team and tackle interdisciplinary challenges that will involve:

  • Design and implementation of a unique and highly sensitive upconversion spectrometer, designed for the molecular fingerprint region.
  • Implementation of a upconversion spectrometer in an electronically controlled XY scanning unit forming a hyperspectral imaging plat form in the 6-10 µm range for wet bio samples.
  • Investigation of hyperspectral imaging for wet bio samples in terms of diagnostics content and specifically answering the question of how thick bio samples that can be used.

As a postdoc, you may be also involved in teaching for a period of up to one month. Experiments will be conducted with a suite of capabilities available at DTU or in collaboration with external partners.

This project is funded by a Lundbeck Experiment Grant.

Qualifications
Candidates should hold a PhD degree in Physics, Photonics Engineering or other science-related discipline. In addition, the candidates may have experience with two or more items listed below: 

  • Nonlinear optics.
  • Mid-IR spectroscopy.
  • Advanced data analysis.
  • Experience with experimental work.
  • Sound background/knowledge in optics is highly desired due to the photonics nature of the instrumentation.
  • Good communication skills in English (both written and oral) are required.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. 

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 2 years. The employment is expected to start on 1 February 2021. 

You can read more about 
career paths at DTU here.  


If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark

Further information
Further information may be obtained from Group Leader Christian Pedersen, email: chrp@fotonik.dtu.dk, tel.: +45 4677 4519. 

You can read more about DTU Fotonik at 
www.fotonik.dtu.dk/english.  

Application procedure
Your complete online application must be submitted no later than 18 January 2021 (Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file.
The file must include:

  • Application (cover letter)
  • CV
  • Academic Diplomas (MSc/PhD)
  • List of publications

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. 

At DTU Photonics Engineering, we research into understanding the nature of light and all the ways in which we can control and use light. Photonics Engineering has become a key enabling technology for our society and is used, for example, both for our communication infrastructure, in the healthcare sector for the treatment of diseases and for secure communication on the Internet.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,000 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. Our main campus is in Kgs. Lyngby north of Copenhagen and we have campuses in Roskilde and Ballerup.