Postdoc in Magnetic Resonance with Nitrogen-Vacancy Diamonds

Tuesday 02 Nov 21

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The aim of this project is to establish an NMR detection setup based on nitrogen-vacancy (NV) defects in diamond and optical detection in combination with hyperpolarization using the dissolution Dynamic Nuclear Polarization (DNP) method that is already established in our lab. Optimal diamond material with NV centers and detection schemes are developed in close collaboration with Profs. Fedor Jelezko and Martin Plenio, Ulm University. The aim of this project is to investigate the metabolism in cells applying hyperpolarized substrates and using NV centers in diamond.

The project is funded by hyperQ (ERC Synergy grant), a collaboration with Profs. Fedor Jelezko and Martin Plenio, Ulm University. Our three groups collaborate closely to realize the goals of this project. In addition, the project will strongly benefit from local collaborations with Kirstine Berg-Sørensen, DTU Health Tech, Magnetic Resonance by Optics group and Alexander Huck, QPIT section at DTU Physics.  

The center for Hyperpolarization in Magnetic Resonance (HYPERMAG) is a center of excellence funded by the Danish National Research Foundation. We are part of the Section for Magnetic Resonance (www.cmr.healthtech.dtu.dk) at the department of Health Technology and conduct research in MRI and NMR. Our research is conducted in collaboration with universities, hospitals, and healthcare companies both nationally and internationally. Our main educational responsibility is within the BSc and MSc program in BioMedical Engineering in collaboration with the Faculty of Health Sciences, University of Copenhagen.

Our mission is to address basic scientific questions of hyperpolarization by Dynamic Nuclear Polarization (DNP) to enable new applications of Magnetic Resonance in the study of biochemical reactions in real-time in vivo and in vitro. The group has high-resolution NMR systems of various types (400MHz and 500MHz with cryoprobe), a 3T clinical MR scanner (GE Healthcare Signa Premier with multinuclear capability), several polarizers (home-built, Hypersense and SpinAligner), a cell lab, chemistry lab and electronics labs. We are 10-15 researchers and support staff.

Responsibilities and qualifications
You will be responsible for
 

  • The development of an experimental setup for NMR detection using NV defects in diamond
  • Combining NV detection of NMR signals with hyperpolarization by dissolution-DNP
  • Applying hyperpolarization and NV detection of NMR signals to investigate metabolism in cellular systems

You should have a PhD degree within the fields of physics, chemistry or equivalent.

Furthermore,

  • you are driven by pushing the boundaries,
  • you enjoy working with complex and challenging topics, and
  • you are motivated by both individual and team accomplishments.

The ideal candidate has

  • experience with NV centers in diamond and/or
  • experience with NMR.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 2 years. Starting as soon as possible.

You can read more about career paths at DTU here.   

Further information
Further information may be obtained from Jan Ardenkjaer-Larsen, +45 4525 3918.


You can read more about DTU Health Tech at www.healthtech.dtu.dk/english.  

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.  

Application procedure
Your complete online application must be submitted no later than 30 November 2021 (Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • Academic Diplomas (MSc/PhD)
  • List of publications

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Techs expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 210 persons, 130 PhD students and a technical/administrative support staff of about 160 persons, of which a large majority contributes to our research infrastructure and related commercial activities.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.