PhD scholarship in Clinical Radiation Dosimetry

Wednesday 28 Aug 19

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Apply no later than 25 September 2019
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The Radiation Physics Division, DTU Nutech, is seeking a candidate for a PhD position to develop geometrical safety concepts suitable for high precision cancer treatment with on-line MR-guided radiotherapy. The work will be carried out in close collaboration with the University Hospitals in Copenhagen and Herlev who have recently acquired state-of-the-art ViewRay MR accelerators. The position is conditional on additional external funding.

The Radiation Physics Division carries out research, innovation and research-based consultancy in the fields of dosimetry, luminescence physics, and neutronics, with applications in geological and archaeological dating, radiation therapy and diagnostics, radiation processing, reactor physics and nuclear emergency preparedness.

The division presently consists of approx. 40 people including researchers, technicians and PhD students.

Background
Radiotherapy with online magnetic resonance (MR) image guidance has recently become commercially available and the clinical implementation is in progress worldwide. The ability to continuously image the irradiated volume while treating the patient requires a new paradigm for treatment planning and dose delivery. The overall objective of this PhD therefore is (i) to define and evaluate the geometric uncertainties in online MR guided radiotherapy, and (ii) to develop quantitative decision support tools to define the treated volume such that this novel technology can be used to its full potential by offering an optimal trade-off between target exposure and normal tissue exposure for the individual patient. The end goal is a new set of guidelines for treatment planning not based on static margins and planned target volume (PTV) as used in conventional radiotherapy.

Job description 
The PhD student will simulate 4D MR motion patterns derived from treated patients with the aim to evaluate dose accumulation for a range of treatment scenarios using different MR-linac gating and tracking procedures. Both geometrically simple targets (e.g. localized prostate) and more complex geometries (e.g. pancreas- and lung tumours) will be used for several patients and sites. The relationship between target coverage and normal tissue exposure will be investigated using Pareto front analysis or similar techniques. The work will primarily be carried out in the clinical environment of the Copenhagen University Hospitals at Herlev and Copenhagen. 

Qualifications
The candidate should have a master's degree or an equivalent degree in engineering, physics, or medical physics with an interest in radiotherapy, imaging, radiation physics, and medical applications of ionizing radiation. 

Approval and Enrollment 
The scholarships for the PhD degree are subject to academic approval, and the candidates will be enrolled in one of the general degree programmes of DTU. For information about the general requirements for enrolment and the general planning of the scholarship studies, please see the DTU PhD Guide.  

We offer
We offer an exciting and challenging job in an international academic environment with excellent possibilities for professional and personal development. The successful candidate will work in an environment with activities and expertise in radiotherapy, radiation physics, dosimetry, radioecology, and medical applications of radionuclides. In addition, the candidate will collaborate closely with Herlev Hospital and Rigshospitalet who has established research groups with >20 PhD students and senior staff. 

Salary and terms of employment 
The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union. The period of employment is 3 years. The candidate should be able to start in 2019.

The formal place of work is DTU Nutech at Risø campus in Roskilde, but the majority of the work will be carried out at Herlev Hospital and Rigshospitalet. 

You can read more about career paths at DTU here

Further information 
Further information may be obtained from Head of Section Claus E. Andersen, clan@dtu.dk, +45 4677 4912, Professor Ivan Richter Vogelius, ivan.richter.vogelius@regionh.dk, +45 3545 9885, or Physicist Claus F. Behrens, Claus.Behrens@regionh.dk, +45 3868 2382.

You can read more about DTU Nutech at www.nutech.dtu.dk/english

Application
We must receive your online application by 25 September 2019 (local time). Follow the link "apply online" and fill in the application form and attach the following files:   

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)
Candidates may apply prior to obtaining their master's degree, but cannot begin before having received it. 

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, race, disability or ethnic background are encouraged to apply.

The Danish national competence center for nuclear technologies. The aim is to develop and utilize knowledge concerning radioactivity and ionizing radiation for the benefit of society.

DTU is a technical university providing internationally leading research, education, innovation and 
scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent