Consultant in Drug Delivery for Gene Transfection Therapies

Friday 28 May 21

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Apply no later than 17 June 2021
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DTU Health Tech is looking for an experienced formulation specialist to join our BII project team working with Locally Sustained Gene Therapy. Experience with lipid and polymer nanoparticle formulations and in vitro cell testing is required.

The job
We are developing novel platform technologies for improved and physiologically adapted gene transfection. The first technologies are focused on transfections systems for cancer immunotherapy.

The successful candidate will join our team of scientists in formulation strategies for delivery of RNA- and DNA-based transfection systems. The candidate will contribute to analysis and quality control of the transfection systems using dynamic light scattering, HPLC, and fluorescence spectroscopy. Additionally, in vitro transfection of cells and flowcytometric analysis will be vital to support the team’s progress.

Responsibilities:

  • Assist the formulation of RNA and DNA transfection vectors
  • Participate in development of depot formulations for release of transfection vectors
  • Contribute to stability studies
  • Assist the bench testing of formulations
  • Provide input in evaluation of in vitro transfection efficiency in cell cultures.
  • Contribute to documentation and communication of obtained results.  

Our expectations of you
You must hold a PhD degree (or equivalent) ideally in chemistry, pharmaceutical or biological science with a focus on formulation and biological evaluation of drug delivery systems.


Qualifications:

  • Knowledge of lipid and polymeric nanoparticles
  • Experience with HPLC analysis and dynamic light scattering
  • Experience with fluorescence spectroscopy
  • Experience with cell cytotoxicity assays and flow cytometry analysis
  • Knowledge of relevant biological targets for cancer therapy is an advantage

What we offer in return
We offer an interesting and challenging job in an international atmosphere with the focus on research, teaching, innovation and scientific advice for the benefit of the surrounding community. We place emphasis on a high level of professionalism among our staff, so skills development is an integral part of our organization. We offer a great flexibility in the position. In the area of technical and natural sciences, DTU is one of the leading research and education institutions in Europe.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union according to your experience and seniority (either Academic Officer or Senior Officer).  


We offer a one-year contract starting 1 August 2021 (or according to mutual agreement).

Application and contact
Please submit your online application no later than Thursday, 17 June 2021 (Danish time). Open the “Apply online” link, fill out the form and attach your motivated application, CV and exam certificates. 


Job interviews are held on an ongoing basis.

If you would like additional information about the position, please contact Associate Professor Jonas R. Henriksen, +45 4058 2866 or Project coordinator Ashley Montgomery, +45 3164 2424.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

DTU Health Tech

DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Techs expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 210 persons, 130 PhD students and a technical/administrative support staff of about 160 persons, of which a large majority contributes to our research infrastructure and related commercial activities.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.