Postdoc in Yeast Engineering and Biomanufacturing

DTU Bioengineering

DTU Bioengineering at the Technical University of Denmark invites applications for a position as Postdoctoral researcher in Yeast Engineering and Biomanufacturing.

This position will be placed at the Yeast Biotechnology and Fermentation group, DTU Bioengineering, section of Synthetic Biology working with gene and genome editing, synthetic biology, regulation engineering, protein production, expression and discovery of bioactive compounds across cell factories, in particular yeast and filamentous fungi.

Responsibilities and qualifications
You will work on a project involving the design and further characterization of non-conventional yeast cell factories for production of recombinant proteins with therapeutic applications, and the development of novel high-throughput methodologies for speeding up the design, engineering and screening of superior production hosts.

In this project you will:

  • Generate an array of non-conventional yeast cell factories able to produce a wide-array of different heterologous proteins of increasing complexity.
  • Perform an "in depth" physiological characterization, screening and further optimization of the target strains by using highly instrumented lab-scale bioreactors combined with a range of -omics analyses and bioinformatic tools.
  • Actively participate in supervision of bachelor and master student projects carried out at the section of synthetic biology.

As a formal qualification, you must hold a PhD degree (or equivalent). Our ideal candidate has several of the following skills:

  • Microbial physiology and molecular biology of yeast (previous experience with non-conventional yeast is a plus).
  • State-of-the-art molecular cloning techniques applied to metabolic engineering and strain design.
  • Quantitative fungal physiology and fermentation technology.
  • Experience with HT-robotics and automation (e.g. BioLector, ROTOR, HAMILTON or similar instruments).
  • A proven solid research experience at international level and a strong publication record in indexed international research journals.

We expect that you are an efficient team worker, have good communication skills, and have a critical approach to formulation and testing of hypotheses. Also, a good sense of humor will be appreciated.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

The period of employment is 2 years. Starting date is 1st of February 2023 or as soon as possible thereafter.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from Associate Professor José Luis Martínez Ruiz, jlmr@dtu.dk or +45 45 25 26 30.

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

Application procedure
Your complete online application must be submitted no later than 1 December 2022 (Danish time).

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV including at least 2 reference contacts
  • Academic Diplomas (MSc/PhD – in English)
  • List of publications

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

The Department of Biotechnology and Biomedicine (DTU Bioengineering) is an international leader in the areas of biotechnology and biomedicine. Our engineering approach to all aspects of biotechnology and biomedicine positions us as a valuable player with unique competences in a growing bio-based economy and with health systems transforming towards personalized medicine. We have a clear focus on the needs in the life science industry and point towards innovation, new businesses, and scientific services for the benefit of society. The department has extensive collaborations with national and international research units and industry. DTU Bioengineering has approx. 400 employees, of which 2/3 are scientific staff. The department is located at DTU Lyngby Campus.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,400 students and 5,800 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.