Protein Engineering (PE)


Protein Engineering

Study Line: Protein Engineering:

  • Protein engineers contribute to the transition towards a sustainable society by optimizing enzyme-based production and degradation of various substances, thereby outcompeting current environmentally damaging solutions.
  • Within this study line, you will obtain competences in analysis and prediction of how the 3D structure of a protein is related to its specific function; and to evaluate how specific proteins should be produced, purified, analyzed, and utilized in industrial processes
  • Focus areas include optimization of protein performance and production using techniques and knowledge from protein design and optimization, protein purification, quality control, crystal structure determination, 3D structure prediction, physical properties, enzyme specificity and  kinetics, assay design, and complex enzyme reactions.

Recomended prequisites for the study line (to be completed during the bachelor education):

  • Experimental biochemistry (exemplified by the DTU course: 27023 Experimental biochemistry)
  • Physical chemistry (exemplified by the DTU course: 26202 Physical chemistry)
  • Bioinformatics (exemplified by the DTU course: 22111 Introduction to Bioinformatics)

General Competence Courses

Mandatory course:

28485 Biobusiness and Process Innovation 5 point Autumn E1B (Thurs 13-17)
42500 Innovation in Engineering 5 point January
42504 Innovation in Engineering 5 point August
42501 Innovation in Engineering 5 point June

A minimum of 20 ETCS must be achieved from the following General Competence Courses courses:

02411 Statistical Design and Analysis of Experiments 5 point Autumn E2A (Mon 13-17), Spring F1A (Mon 8-12)
27230 Prokaryotic cell biology 5 point Autumn E1A (Mon 8-12)
27423 Metabolomics and proteomics 5 point Autumn E3A (Tues 8-12)
27430 Eukaryotic cell biology 5 point Autumn E2B (Thurs 8-12)
27460 Synthetic biology 5 point Autumn E5A (Wed 8-12)
27641 Systems biology 5 point Autumn E5B (Wed 13-17)
28857 Good Manufacturing Practice (GMP) and quality in pharmaceutical, biotech and food industry - Practical version 7.5 point Autumn E1B (Thurs 13-17) and Autumn E3B (Fri 13-17)
28855 Good Manufacturing Practice (GMP) and quality in pharmaceutical, biotech and food industry - Theoretical version 5 point Spring F1B (Thurs 13-17)

Technological Specialization Courses

At least 30 ETCS should be selected among the following courses, of which 27302 (Quantitative analysis and modeling in protein science), 27325 (Protein structure determination - not yet offered), and 22117 (Protein structure and computational biology) are highly recommended:

22117 Protein structure and computational biology 5 point Spring F5A (Wed 8-12)
26125 Chromatographic (HPLC) Purification of Biological Macromolecules 5 point June
27101 Assay Technology 5 point June
27246 Applied enzyme technology and kinetics 5 point E7 (Tues 18-22)
27247 Experimental enzyme technology 5 point Autumn E1A (Mon 8-12)
27325 Advanced protein structure engineering and analysis 5 point Spring F2A (Mon 13-17)
27330 Quantitative analysis and modeling in protein science 5 point Spring F3B (Fri 13-17)