Fermentation Based Manufacturing (FBM)

 

Sustainable production of chemical and biochemical products is increasingly based on fermentation processes rooted in biology and living organisms. Development and scaling-up of such processes to successful production, as well as operation and optimization of existing production facilities require engineers who have a firm basis in both process technology and biological, cell related manufacturing issues. 

The FBM study line addresses the need for engineers with an education combining process technology and biotechnology. It is common with the FBM study line under MSc Biotechnology with which it shares a common core of mandatory elements. The two FBM study lines are supported by a large grant (the FBM Initiative) to develop and increase competence transfer between the two educations for nurturing industrially required cross competence fermentation experts. Each of the two study lines, however, retains priorities of their parent programmes, so that outside the FBM core the study line under MSc Chemical and Biochemical Engineering is structured to satisfy the aims of being Chemical and Biochemical Engineering.    

Engineers from this study line will obtain competences in designing, implementing and operating fermentation based production by combining process technology with cell factory engineering. Engineers from this study line will be instrumental in driving chemical production towards sustainable goals.

Fermentation Based Manufacturing (FBM)

Sustainable production of chemical and biochemical products is increasingly based on fermentation processes rooted in biology and living organisms. Development and scaling-up of such processes to successful production, as well as operation and optimization of existing production facilities require engineers who have a firm basis in both process technology and biological, cell related manufacturing issues.

The FBM study line addresses the need for engineers with an education combining process technology and biotechnology. It is common with the FBM study line under MSc Biotechnology with which it shares a common core of mandatory elements. The two FBM study lines are supported by a large grant (the FBM Initiative) to develop and increase competence transfer between the two educations for nurturing industrially required cross competence fermentation experts. Each of the two study lines, however, retains priorities of their parent programmes, so that outside the FBM core the study line under MSc Chemical and Biochemical Engineering is structured to satisfy the aims of being Chemical and Biochemical Engineering.    

Engineers from this study line will obtain competences in designing, implementing and operating fermentation based production by combining process technology with cell factory engineering. Engineers from this study line will be instrumental in driving chemical production towards sustainable goals.

FBM study line curriculum

Recommended additional prerequisites for the study line (preferably to be completed during the bachelor education):
See notes under admission requirements.
 
General competence courses
Mandatory courses (Group C):

28485 Biobusiness and Process Innovation 5 point Autumn E1B (Thurs 13-17)
28855 Good Manufacturing Practice (GMP) and quality in pharmaceutical, biotech and food industry - Theoretical version 5 point Spring F1B (Thurs 13-17)
or
28857 Good Manufacturing Practice (GMP) and quality in pharmaceutical, biotech and food industry - Practical version 7.5 point Autumn E1B (Thurs 13-17) and Autumn E3B (Fri 13-17)
42500 Innovation in Engineering 5 point January
or
42504 Innovation in Engineering 5 point August
or
42501 Innovation in Engineering 5 point June

Remaining general competence courses should be chosen such that the requirements of at least one course in Group A and one course in Group B are satisfied.
 
Technological specialization courses 
Mandatory courses:

27455 Microbial adaptation to industrial processes 5 point Spring F2B (Thurs 8-12)
28455 Process adaptation in Fermentation Based Biomanufacturing 5 point Autumn E2B (Thurs 8-12)

 

Strongly recommended courses:

27410 Computer-aided cell factory design 5 point Autumn E4A (Tues 13-17)
28233 Recovery and purification of biological products 5 point Autumn E2A (Mon 13-17)
28345 Industrial BioReaction Engineering 5 point Spring F4A (Tues 13-17)

These courses are prerequisites for other courses and elements in the study line, or they are important for study line competences. Many bachelor educations include courses on those subjects, but if not part of the admission giving bachelor programme, these courses should be part of the study plan.
 
Electives
Mandatory:
Practical course ("Internship") in a biotech company or DTU pilot facility. 10-15 ECTS. The practical course must be registered as a project course, and the content and evaluation form must be approved by the Head of Studies and/or the FBM coordinator as being within the FBM study line.
Unrestricted electives:
10-17.5 ECTS
 
MSc Thesis
30-35 ECTS. The subject must be approved by the Head of Studies and/or FBM coordinator as being within the FBM study line and must be approved by the Head of Studies as being within the area of MSc Chemical and Biochemical Engineering.

Students who want to obtain this study line designation must ensure that FBM mandatory courses are retained.

Two examples are shown: one for students beginning their MSc study in September, and one for students beginning their MSc study in February.

The study plans are examples only. Students are free to exchange the shown courses with other courses as long as general competence (GC) and technological specialization (TS) requirements are satisfied. 

The plans satisfy GC and TS requirements. Some electives are specified as additional GC or TS courses.

Any DTU MSc level course may be used as elective. Courses from DTU Bioengineering (27xyz) may be particularly relevant for the Fermentation Based Manufacturing study line.

Study plan examples - Fermentation Based Manufacturing

Study plan for September start:

General competences
Technological specialization
Thesis
Electives
1.Semester
28530
Transport Processes
10 point
42500
Innovation in Engineering
5 point
28233
Recovery and purification of biological... Recovery and purification of biological products
5 point
28420
Separation Processes
7.5 point
2.Semester
28350
Process Design: Principles and Methods
10 point
28855
Good Manufacturing Practice (GMP) and... Good Manufacturing Practice (GMP) and quality in pharmaceutical, biotech and food industry - Theoretical version
5 point
27455
Microbial adaptation to industrial... Microbial adaptation to industrial processes
5 point
28345
Industrial BioReaction Engineering
5 point
28434
Membrane Technology
5 point
3.Semester
28485
Biobusiness and Process Innovation
5 point
28455
Process adaptation in Fermentation Based... Process adaptation in Fermentation Based Biomanufacturing
5 point
Elective
FBM Industrial Internship (Project course)
10 point
27410
Computer-aided cell factory design
5 point
4.Semester
SPEC
MSc Thesis
30 point

Study plan for February start:

General competences
Technological specialization
Thesis
Electives
1.Semester
28361
Chemical engineering model analysis
7.5 point
42501
Innovation in Engineering
5 point
28345
Industrial BioReaction Engineering
5 point
28434
Membrane Technology
5 point
28451
Optimising Plantwide Control
7.5 point
2.Semester
28485
Biobusiness and Process Innovation
5 point
28455
Process adaptation in Fermentation Based... Process adaptation in Fermentation Based Biomanufacturing
5 point
28233
Recovery and purification of biological... Recovery and purification of biological products
5 point
27410
Computer-aided cell factory design
5 point
3.Semester
28350
Process Design: Principles and Methods
10 point
28855
Good Manufacturing Practice (GMP) and... Good Manufacturing Practice (GMP) and quality in pharmaceutical, biotech and food industry - Theoretical version
5 point
27455
Microbial adaptation to industrial... Microbial adaptation to industrial processes
5 point
Elective
FBM Industrial Internship (Project course)
10 point
4.Semester
SPEC
MSc Thesis
30 point