Magnus Karlsson

Magnus Karlsson

Senior Researcher

DTU HEALTH TECH
Department of Health Technology

Technical University of Denmark

Ørsteds Plads

Building 349, room 114

2800 Kgs. Lyngby

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2019
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Analysis of dDNP NMR metabolic data from cancer cells

Frahm, Anne Birk ; Lundsgaard, E. ; Matei, A. ; Jensen, Pernille Rose ; Karlsson, Magnus ; Ardenkjær-Larsen, Jan Henrik ; Lerche, Mathilde Hauge
Presented at:
International Conference on Nuclear Hyperpolarization 2018

Type: Conference abstract for conference (Peer reviewed)

Status: Accepted/In press     |    Year: 2019

 

Gadolinium Effect at High-Magnetic-Field DNP: 70% 13C Polarization of [U-13C] Glucose Using Trityl

Capozzi, Andrea ; Patel, Saket ; Wenckebach, W. Thomas ; Karlsson, Magnus ; Lerche, Mathilde H. ; Ardenkjær-Larsen, Jan Henrik
in: Journal of Physical Chemistry Letters, vol: 10, pages: 3420-3425

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1021/acs.jpclett.9b01306

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Rapid zero-trans kinetics of Cs+ exchange in human erythrocytes quantified by dissolution hyperpolarized 133Cs+ NMR spectroscopy

Kuchel, Philip William ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Shishmarev, Dmitry ; Ardenkjær-Larsen, Jan Henrik
in: Scientific Reports, vol: 9, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1038/s41598-019-56250-z

 

Real-Time Detection of Intermediates in Rhodium Catalyzed Hydrogenation of Alkynes and Alkenes by Dissolution DNP

Boeg, Peter Andreas ; Duus, Jens Øllgaard ; Ardenkjær-Larsen, Jan Henrik ; Karlsson, Magnus ; Mossin, Susanne
in: The Journal of Physical Chemistry Part C, vol: 123, issue: 15, pages: 9949-9956

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1021/acs.jpcc.9b01376

 

Targeted Metabolomics with Quantitative Dissolution Dynamic Nuclear Polarization

Lerche, Mathilde Hauge ; Karlsson, Magnus ; Ardenkjær-Larsen, Jan Henrik ; Jensen, Pernille Rose
part of: NMR-Based Metabolomics, pages: 385-393, 2019, Springer

Type: Book chapter (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1007/978-1-4939-9690-2_21

2018
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Analysis of dDNP NMR metabolic data from cancer cells (- poster)

Frahm, Anne Birk ; Lundsgaard, Emma Alberte ; Matei, Amalia ; Jensen, Pernille Rose ; Karlsson, Magnus ; Ardenkjær-Larsen, Jan Henrik ; Lerche, Mathilde Hauge
Presented at:
International Conference on Nuclear Hyperpolarization 2018

Type: Poster (Peer reviewed)

Status: Published     |    Year: 2018

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A narrow line UV-induced non-persistent radical to generate highly polarized transportable glucose solid samples

Capozzi, Andrea ; Patel, S ; Ouari, Olivier ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Comment, Arnaud ; Ardenkjær-Larsen, Jan Henrik
Presented at:
59th Experimental Nuclear Magnetic Resonance Conference

Type: Conference abstract for conference (Peer reviewed)

Status: Published     |    Year: 2018

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Efficient Hyperpolarization of U-13 C-Glucose Using Narrow-Line UV-Generated Labile Free Radicals

Capozzi, Andrea ; Patel, Saket ; Gunnarsson, Christine Pepke ; Marco-Rius, Irene ; Comment, Arnaud ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Ouari, Olivier ; Ardenkjær-Larsen, Jan Henrik
in: ANGEWANDTE CHEMIE, vol: 57, pages: 1 – 6

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1002/anie.201810522

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Liquid-State Polarization of 30% through Photo-Induced Non-Persistent Radicals on 13C Pyruvic Acid

Capozzi, Andrea ; Karlsson, Magnus ; Petersen, Jan Raagaard ; Lerche, Mathilde Hauge ; Ardenkjær-Larsen, Jan Henrik
Presented at:
59th Experimental Nuclear Magnetic Resonance Conference

Type: Conference abstract for conference (Peer reviewed)

Status: Published     |    Year: 2018

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Liquid-State 13C Polarization of 30% through Photoinduced Nonpersistent Radicals

Capozzi, Andrea ; Karlsson, Magnus ; Petersen, Jan Raagaard ; Lerche, Mathilde Hauge ; Ardenkjær-Larsen, Jan Henrik
in: Journal of Physical Chemistry C, vol: 122, issue: 13, pages: 7432-7443

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1021/acs.jpcc.8b01482

2017
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A narrow line UV-induced non-persistent radical in view of generating highly polarized transportable glucose solid samples

Capozzi, Andrea ; Coi, Alessandro ; Patel, S ; Ouari, Olivier ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Comment, Arnaud ; Ardenkjær-Larsen, Jan Henrik
Presented at:
EUROMAR 2017

Type: Conference abstract for conference

Status: Published     |    Year: 2017

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dDNP as an emergent real time analytical method for catalytic reactions

Boeg, Peter Andreas ; Mossin, Susanne ; Duus, Jens Øllgaard ; Ardenkjær-Larsen, Jan Henrik ; Karlsson, Magnus
Presented at:
EUROMAR 2017

Type: Conference abstract for conference (Peer reviewed)

Status: Published     |    Year: 2017

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dDNP as an emerging real time analytical method for catalytic reactions

Boeg, Peter Andreas ; Mossin, Susanne ; Duus, Jens Øllgaard ; Ardenkjær-Larsen, Jan Henrik ; Karlsson, Magnus
Presented at:
EUROMAR 2017

Type: Conference abstract for conference (Peer reviewed)

Status: Published     |    Year: 2017

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Detecting Elusive Intermediates in Carbohydrate Conversion: A Dynamic Ensemble of Acyclic Glucose-Catalyst Complexes

Meier, Sebastian ; Karlsson, Magnus ; Jensen, Pernille Rose
in: ACS Sustainable Chemistry & Engineering, vol: 5, issue: 6, pages: 5571-5577

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1021/acssuschemeng.7b00985

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Hyperpolarized 133Cs is a sensitive probe for real-time monitoring of biophysical environments

Karlsson, Magnus ; Ardenkjær-Larsen, Jan Henrik ; Lerche, Mathilde Hauge
in: Chemical Communications, vol: 53, issue: 49, pages: 6625-6628

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1039/C7CC02943H

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Measuring glucose cerebral metabolism in the healthy mouse using hyperpolarized C-13 magnetic resonance

Mishkovsky, Mor ; Anderson, Brian ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Sherry, A. Dean ; Gruetter, Rolf ; Kovacs, Zoltan ; Comment, Arnaud
in: Scientific Reports, vol: 7, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1038/s41598-017-12086-z

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Preparation of Radical-Free Hyperpolarized Water using Photo-induced non-persistent Radicals on a “SpinLab-like” dissolution-DNP Polarizer

Capozzi, Andrea ; Coi, Alessandro ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Ardenkjær-Larsen, Jan Henrik
Presented at:
58th Experimental Nuclear Magnetic Resonance Conference

Type: Conference abstract for conference (Peer reviewed)

Status: Published     |    Year: 2017

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Quantifying Biochemical Activities in Living Cells with 13C dDNP NMR

Jensen, Pernille Rose ; Karlsson, Magnus ; Capozzi, Andrea ; Ardenkjær-Larsen, Jan Henrik ; Lerche, Mathilde Hauge
Presented at:
International Society of Magnetic Resonance

Type: Conference abstract for conference (Peer reviewed)

Status: Published     |    Year: 2017

2016
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Hyperpolarized 1-13c-1,1-bis(acetoxy(methyl))-2,2'-cyclopropane as metabolic marker for mr

Lerche, Mathilde Hauge ; Jensen, Pernille Rose ; Karlsson, Magnus ; Napolitano, Roberta (Inventor) ; Cabella, Claudia (Inventor) ; Miragoli, Luigi (Inventor) ; Colombo Serra, Sonia (Inventor) ; Tedoldi, Fabio (Inventor)
Patent no.: EP3016687, Date: 2015-01-08

Type: Patent

Status: Published     |    Year: 2016

 

High-field dissolution dynamic nuclear polarization of [1-13C]pyruvic acid

Yoshihara, Hikari A. I. ; Can, Emine ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Schwitter, Juerg ; Comment, Arnaud
in: Physical Chemistry Chemical Physics, vol: 18, issue: 18, pages: 12409-12413

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: https://doi.org/10.1039/c6cp00589f

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Probing treatment response of glutaminolytic prostate cancer cells to natural drugs with hyperpolarized [5-13C]glutamine

Jensen, Pernille Rose ; Canape, Carolina ; Catanzaro, Giuseppina ; Karlsson, Magnus ; Lerche, Mathilde Hauge
Presented at:
2016 World Molecular Imaging Congress

Type: Poster (Peer reviewed)

Status: Published     |    Year: 2016

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Single-Shot-RARE for rapid 3D hyperpolarized metabolic ex vivo tissue imaging: RF-pulse design for semi-dense spectra

Magnusson, P.O. ; Jensen, Pernille Rose ; Dyrby, Tim Bjørn ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Hanson, Lars G.
Presented at:
33rd ESMRMB Annual Scientific Meeting

Type: Poster (Peer reviewed)

Status: Published     |    Year: 2016

2015
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Hyperpolarized esters as metabolic markers in mr

Jensen, Pernille Rose ; Lerche, Mathilde Hauge ; Karlsson, Magnus ; Cabella, Claudia (Inventor) ; Colombo Serra, Sonia (Inventor) ; Miragoli, Luigi (Inventor) ; Venturi, Luca (Inventor) ; Tedoldi, Fabio (Inventor)
Patent no.: EP2950826, Date: 2015-12-09

Type: Patent

Status: Published     |    Year: 2015

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Hyperpolarized 2-oxoglutarate as metabolic agent in mr

Jensen, Pernille Rose ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Cabella, Claudia (Inventor) ; Caminiti, Lara (Inventor) ; Colombo Serra, Sonia (Inventor) ; Miragoli, Luigi (Inventor) ; Poggi, Luisa (Inventor) ; Venturi , Luca (Inventor) ; Tedoldi, Fabio (Inventor)
Patent no.: EP2911704, Date: 2015-09-02

Type: Patent

Status: Published     |    Year: 2015

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Triarylmethyl radicals.

Karlsson, Magnus ; Napolitano, Roberta (Inventor) ; Visigalli , Massimo (Inventor) ; Lerche, Mathilde Hauge ; Jensen, Pernille Rose ; Tedoldi, Fabio (Inventor)
Patent no.: EP2872520, Date: 2015-05-20

Type: Patent

Status: Published     |    Year: 2015

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Intra-operative cancer diagnosis based on a hyperpolarized marker

Lerche, Mathilde Hauge ; Karlsson, Magnus ; Jensen, Pernille Rose
Patent no.: EP2847591, Date: 2015-03-18

Type: Patent

Status: Published     |    Year: 2015

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Hyperpolarized amino acids

Karlsson, Magnus ; Lerche, Mathilde Hauge ; Jensen, Pernille Rose
Patent no.: EP2833924, Date: 2015-02-11

Type: Patent

Status: Published     |    Year: 2015

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3D metabolic ex vivo sample imaging of hyperpolarized compounds using a 3D single-shot RARE (3D SS-RARE) sequence, combining spectral RF selectivity with under-sampled spectral encoding at signal read-out

Magnusson, P.O. ; Jensen, Pernille Rose ; Dyrby, T. B. ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Hanson, Lars G.
part of: Proceedings of 5th hyperpolarization symposium, pages: 105, 2015
Presented at:
Hyperpolarized Magnetic Resonance

Type: Conference abstract in proceedings (Peer reviewed)

Status: Published     |    Year: 2015

 

Hyperpolarized [1,3-C-13(2)]ethyl acetoacetate is a novel diagnostic metabolic marker of liver cancer

Jensen, Pernille Rose ; Serra, Sonia Colombo ; Miragoli, Luigi ; Karlsson, Magnus ; Cabella, Claudia ; Poggi, Luisa ; Venturi, Luca ; Tedoldi, Fabio ; Lerche, Mathilde Hauge
in: International Journal of Cancer, vol: 136, issue: 4, pages: E117-E126

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: https://doi.org/10.1002/ijc.29162

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Myocardial fatty acid metabolism probed with hyperpolarized [1-13C]octanoate

Yoshihara, Hikari ; Bastiaansen, Jessica A. ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Comment, Arnaud ; Schwitter, Juerg
in: Journal of Cardiovascular Magnetic Resonance, vol: 17, issue: Suppl. 1, pages: 1-2

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: https://doi.org/10.1186/1532-429X-17-S1-O101

 

NMR Insights into the Inner Workings of Living Cells

Lerche, Mathilde Hauge ; Jensen, Pernille Rose ; Karlsson, Magnus ; Meier, Sebastian
in: Analytical chemistry, vol: 87, pages: 119−132

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: https://doi.org/10.1021/ac501467x

 

Probing treatment response of glutaminolytic prostate cancer cells to natural drugs with hyperpolarized [5-C-13]glutamine

Canape, Carolina ; Catanzaro, Giuseppina ; Terreno, Enzo ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Jensen, Pernille Rose
in: Magnetic Resonance in Medicine, vol: 73, issue: 6, pages: 2296-2305

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: https://doi.org/10.1002/mrm.25360

2014
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Process for the preparation of hyperpolarized derivatives for use in mri analysis

Aime, Silvio (Inventor) ; Battista Giovenzana, Giovanni (Inventor) ; Tedoldi, Fabio (Inventor) ; Jensen, Pernille Rose ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Colombo Serra, Sonia (Inventor)
Patent no.: EP2766050, Date: 2014-08-20

Type: Patent

Status: Published     |    Year: 2014

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Hyperpolarized NMR Probes for Biological Assays

Meier, Sebastian ; Jensen, Pernille Rose ; Karlsson, Magnus ; Lerche, Mathilde Hauge
in: Sensors, vol: 14, issue: 1, pages: 1576-1597

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2014     |    DOI: https://doi.org/10.3390/s140101576

 

Non-invasive in-cell determination of free cytosolic [NAD+]/ [NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes

Christensen, Caspar Elo ; Karlsson, Magnus ; Winther, Jakob R. ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge
in: Journal of Biological Chemistry, vol: 289, issue: 4, pages: 2344-2352

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2014     |    DOI: https://doi.org/10.1074/jbc.M113.498626

2013
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Composition comprising acetic anhydride and a gadolinium complex, and method for the use in hyperpolarisation mri analysis.

Lerche, Mathilde Hauge ; Karlsson, Magnus ; Jensen, Pernille Rose ; Colombo Serra, Sonia (Inventor) ; Visigalli, Massimo (Inventor) ; Aime, Silvio (Inventor) ; Tedoldi, Fabio (Inventor)
Patent no.: WO2013083535, Date: 2013-06-13

Type: Patent

Status: Published     |    Year: 2013

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Process for preparing hyperpolarized substrates and method for mri

Aime, Silvio (Inventor) ; Battista Giovenzana, Giovanni (Inventor) ; Tedoldi, Fabio (Inventor) ; Maiocchi, Alessandro (Inventor) ; Uggeri, Fulvio (Inventor) ; Jensen, Pernille Rose ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Visigalli , Massimo (Inventor) ; Crosetti, Marco (Inventor) ; Poggi, Luisa (Inventor)
Patent no.: EP2555803, Date: 2013-02-13

Type: Patent

Status: Published     |    Year: 2013

 

In vivo and in vitro liver cancer metabolism observed with hyperpolarized [5-C-13]glutamine

Cabella, C. ; Karlsson, Magnus ; Canape, C. ; Catanzaro, G. ; Serra, S. Colombo ; Miragoli, L. ; Poggi, L. ; Uggeri, F. ; Venturi, L. ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge ; Tedoldi, F.
in: Journal of Magnetic Resonance, vol: 232, pages: 45-52

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2013     |    DOI: https://doi.org/10.1016/j.jmr.2013.04.010

 

N-15-Permethylated amino acids as efficient probes for MRI-DNP applications

Chiavazza, Enrico ; Viale, Alessandra ; Karlsson, Magnus ; Aime, Silvio
in: Contrast Media & Molecular Imaging, vol: 8, issue: 5, pages: 417-421

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2013     |    DOI: https://doi.org/10.1002/cmmi.1538

 

Real-Time DNP NMR Observations of Acetic Acid Uptake, Intracellular Acidification, and of Consequences for Glycolysis and Alcoholic Fermentation in Yeast

Jensen, Pernille Rose ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Meier, Sebastian
in: Chemistry: A European Journal, vol: 19, pages: 13288 – 13293

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2013     |    DOI: https://doi.org/10.1002/chem.201302429

2012
 

Development of Dissolution DNP-MR Substrates for Metabolic Research

Karlsson, Magnus ; Jensen, Pernille Rose ; Duus, Jens Øllgaard ; Meier, Sebastian ; Lerche, Mathilde Hauge
in: Applied Magnetic Resonance, vol: 43, issue: 1-2, pages: 223-236

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2012     |    DOI: https://doi.org/10.1007/s00723-012-0336-7

 

Hyperpolarized 13C-labelled anhydrides as DNP precursors of metabolic MRI agents

Serra, Sonia Colombo ; Karlsson, Magnus ; Giovenzana, Giovanni Battista ; Cavallotti, Camilla ; Tedoldi, Fabio ; Aime, Silvio
in: Contrast Media & Molecular Imaging, vol: 7, issue: 5, pages: 469-477

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2012     |    DOI: https://doi.org/10.1002/cmmi.1474

2011
 

A hyperpolarized choline molecular probe for monitoring acetylcholine synthesis

Allouche-Arnon, Hyla ; Gamliel, Ayelet ; Barzilay, Claudia M. ; Nalbandian, Ruppen ; Gomori, J. Moshe ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Katz-Brull, Rachel
in: Contrast Media & Molecular Imaging, vol: 6, issue: 3, pages: 139-147

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2011     |    DOI: https://doi.org/10.1002/cmmi.418

 

Detection of tumor glutamate metabolism in vivo using 13C magnetic resonance spectroscopy and hyperpolarized [1- 13C]glutamate

Gallagher, Ferdia A. ; Kettunen, Mikko I. ; Day, Sam E. ; Hu, De En ; Karlsson, Magnus ; Gisselsson, Anna ; Lerche, Mathilde Hauge ; Brindle, Kevin M.
in: Magnetic Resonance in Medicine, vol: 66, issue: 1, pages: 18-23

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2011     |    DOI: https://doi.org/10.1002/mrm.22851

 

Deuteration of a molecular probe for DNP hyperpolarization - a new approach and validation for choline chloride

Allouche-Arnon, Hyla ; Lerche, Mathilde Hauge ; Karlsson, Magnus ; Lenkinski, Robert E. ; Katz-Brull, Rachel
in: Contrast Media & Molecular Imaging, vol: 6, issue: 6, pages: 499-506

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2011     |    DOI: https://doi.org/10.1002/cmmi.452

 

Metabolic pathway visualization in living yeast by DNP-NMR

Meier, Sebastian ; Karlsson, Magnus ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge ; Duus, Jens Øllgaard
in: Molecular BioSystems, vol: 7, issue: 10, pages: 2834-2836

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2011     |    DOI: https://doi.org/10.1039/c1mb05202k

 

Quantitative dynamic nuclear polarization‐NMR on blood plasma for assays of drug metabolism

Lerche, Mathilde Hauge ; Meier, Sebastian ; Jensen, Pernille Rose ; Hustvedt, Svein‐Olaf ; Karlsson, Magnus ; Duus, Jens Øllgaard ; Ardenkjær-Larsen, Jan Henrik
in: N M R in Biomedicine, vol: 24, issue: 1, pages: 96-103

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2011     |    DOI: https://doi.org/10.1002/nbm.1561

2010
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Mr imaging agent or medium compressing hzperpolarised 13c alanine and methods of imaging wherein such an imaging medium is used.

Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; Månsson, Sven (Inventor) ; In't Zandt , Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge
Patent no.: EP2237801, Date: 2010-10-13

Type: Patent

Status: Published     |    Year: 2010

 

Imaging of branched chain amino acid metabolism in tumors with hyperpolarized 13C ketoisocaproate

Karlsson, Magnus ; Jensen, Pernille Rose ; in 't Zandt, René ; Gisselsson, Anna ; Hansson, Georg ; Duus, Jens Øllgaard ; Meier, Sebastian ; Lerche, Mathilde Hauge
in: International Journal of Cancer, vol: 127, issue: 3, pages: 729-736

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2010     |    DOI: https://doi.org/10.1002/ijc.25072

 

Study of molecular interactions with 13C DNP-NMR

Lerche, Mathilde Hauge ; Meier, Sebastian ; Jensen, Pernille Rose ; Baumann, Herbert ; Petersen, Bent O. ; Karlsson, Magnus ; Duus, Jens Øllgaard ; Ardenkjær-Larsen, Jan Henrik
in: Journal of Magnetic Resonance, vol: 203, issue: 1, pages: 52-56

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2010     |    DOI: https://doi.org/10.1016/j.jmr.2009.11.020

2009
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Method to produce hyperpolarised amino acids and aminosulphonic acids

Lerche, Mathilde Hauge ; Karlsson, Magnus ; Jensen, Pernille Rose
Patent no.: WO2009098191, Date: 2009-08-13

Type: Patent

Status: Published     |    Year: 2009

  PDF

Mr imaging agent or medium compressing hyperpolarised 13c alanine and methods of imaging wherein such an imaging medium is used.

Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; Maansson, Sven (Inventor) ; Zandt, Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge
Patent no.: WO2009098192, Date: 2009-08-13

Type: Patent

Status: Published     |    Year: 2009

  PDF

Mr imaging agent, imaging medium and methods of imaging wherein such an imaging medium is used

Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; Maansson, Sven (Inventor) ; Zandt , Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge
Patent no.: WO2009080739, Date: 2009-07-02

Type: Patent

Status: Published     |    Year: 2009

  PDF

Composition and method for generating a metabolic profile using 13c-mr detection

Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; Maansson, Sven (Inventor) ; Zandt , Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge
Patent no.: WO2009077575, Date: 2009-06-25

Type: Patent

Status: Published     |    Year: 2009

  PDF

Imaging medium comprising hyperpolarised 13c-acetate and use thereof

Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; Maansson, Sven (Inventor) ; Zandt, Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge
Patent no.: WO2009027388, Date: 2009-03-05

Type: Patent

Status: Published     |    Year: 2009

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Imaging medium comprising hyperpolarised 13 c-lactate and use thereof.

Lerche, Mathilde Hauge ; Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; MAANSSON,, SVEN (Inventor) ; Zandt, Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose
Patent no.: WO2009013350, Date: 2009-01-29

Type: Patent

Status: Published     |    Year: 2009

 

Detection of low-populated reaction intermediates with hyperpolarized NMR

Jensen, Pernille Rose ; Meier, Sebastian ; Ardenkjær-Larsen, Jan Henrik ; Duus, Jens Øllgaard ; Karlsson, Magnus ; Lerche, Mathilde Hauge
in: Chemical Communications, vol: 2009, issue: 34, pages: 5168-5170

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2009     |    DOI: https://doi.org/10.1039/b910626j

 

Hyperpolarized Amino Acids for In Vivo Assays of Transaminase Activity

Jensen, Pernille Rose ; Karlsson, Magnus ; Meier, Sebastian ; Duus, Jens Øllgaard ; Lerche, Mathilde Hauge
in: Chemistry: A European Journal, vol: 15, issue: 39, pages: 10010-10012

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2009     |    DOI: https://doi.org/10.1002/chem.200901042

 

Production of hyperpolarized [1,4-C-13(2)]malate from [1,4-C-13(2)]fumarate is a marker of cell necrosis and treatment response in tumors

Gallagher, Ferdia A. ; Kettunen, Mikko I. ; Hu, De-En ; Jensen, Pernille Rose ; in't Zandt, Rene ; Karlsson, Magnus ; Gisselsson, Anna ; Nelson, Sarah K. ; Witney, Timothy H. ; Bohndiek, Sarah E. ; Hansson, Georg ; Peitersen, Torben ; Lerche, Mathilde Hauge ; Brindle, Kevin M.
in: Proceedings of the National Academy of Sciences of the United States of America, vol: 106, issue: 47, pages: 19801-19806

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2009     |    DOI: https://doi.org/10.1073/pnas.0911447106

 

Tissue-specific Short Chain Fatty Acid Metabolism and Slow Metabolic Recovery after Ischemia from Hyperpolarized NMR in Vivo

Jensen, Pernille Rose ; Peitersen, Torben ; Karlsson, Magnus ; in't Zandt, Rene ; Gisselsson, Anna ; Hansson, Georg ; Meier, Sebastian ; Lerche, Mathilde Hauge
in: Journal of Biological Chemistry, vol: 284, issue: 52, pages: 36077-36082

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2009     |    DOI: https://doi.org/10.1074/jbc.M109.066407

2008
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Method to produce hyperpolarised carboxylates and sulphonates in the presence of inorganic cations.

Lerche, Mathilde Hauge ; Karlsson, Magnus
Patent no.: EP1998813, Date: 2007-03-21

Type: Patent

Status: Published     |    Year: 2008

 

Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate.

Gallagher, Ferdia A ; Kettunen, Mikko I ; Day, Sam E. ; Hu, De-En ; Ardenkjær-Larsen, Jan Henrik ; Zandt, René in 't ; Jensen, Pernille Rose ; Karlsson, Magnus ; Golman, Klaes ; Lerche, Mathilde Hauge ; Brindle, Kevin M
in: Nature, vol: 453, issue: 7197, pages: 940-943

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2008     |    DOI: https://doi.org/10.1038/nature07017

2006
 

Hydrocarboxylation of olefins using an amphiphilic palladium catalyst, activity and recycling properties NMR identification of some reaction intermediates

Karlsson, Magnus ; Ionescu, Adriana ; Andersson, Carlaxel
in: Journal of Molecular Catalysis A: Chemical, vol: 259, issue: 1-2, pages: 231-237

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2006     |    DOI: https://doi.org/10.1016/j.molcata.2006.06.036

2005
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Tungsten particles as x-ray contrast agents

Axelsson, Oskar (Inventor) ; Leunbach, Ib (Inventor) ; Karlsson, Magnus
Patent no.: WO2005051435, Date: 2005-06-09

Type: Patent

Status: Published     |    Year: 2005

 

Design and implementation of 13C hyper polarization from para-hydrogen, for new MRI contrast agents

Goldman, Maurice ; Jóhannesson, Haukur ; Axelsson, Oskar ; Karlsson, Magnus
in: Comptes Rendus Chimie, vol: 9, issue: 3-4, pages: 357-363

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2005     |    DOI: https://doi.org/10.1016/j.crci.2005.05.010

 

Hyperpolarization of 13C through order transfer from parahydrogen: A new contrast agent for MRI

Goldman, Maurice ; Jóhannesson, Haukur ; Axelsson, Oskar ; Karlsson, Magnus
in: Magnetic Resonance Imaging, vol: 23, issue: 2, pages: 153-157

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2005     |    DOI: https://doi.org/10.1016/j.mri.2004.11.031

2004
 

Transfer of para-hydrogen spin order into polarization by diabatic field cycling

Jóhannesson, Haukur ; Axelsson, Oskar ; Karlsson, Magnus
in: Comptes Rendus Physique, vol: 5, issue: 3, pages: 315-324

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2004     |    DOI: https://doi.org/10.1016/j.crhy.2004.02.001

2003
 

Molecular imaging using hyperpolarized 13C

Golman, K ; Olsson, L E ; Axelsson, O ; Månsson, Sven-Erik ; Karlsson, Magnus ; Petersson, J S
in: British Journal of Radiology, vol: 76 Spec No 2, pages: S118-27

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2003     |    DOI: https://doi.org/10.1259/bjr/26631666

2002
 

A simple protocol to enhance the recycling properties of amphiphilic rhodium hydroformylation catalysts

Karlsson, Magnus ; Andersson, Carlaxel
in: Catalysis Communications, vol: 3, issue: 1, pages: 1-5

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2002     |    DOI: https://doi.org/10.1016/S1566-7367(01)00066-8

2001
 

Hydroformylation of propene and 1-hexene catalysed by a alpha-zirconium phosphate supported rhodium-phosphine complex

Karlsson, Magnus ; Andersson, C ; Hjortkjær, Jes
in: Journal of Molecular Catalysis A: Chemical, vol: 166, issue: 2, pages: 337-343

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2001     |    DOI: https://doi.org/10.1016/S1381-1169(00)00480-5

1999
 

Synthesis, characterisation and ligand properties of a new amphiphilic triphenylphosphine analogue †

Karlsson, Magnus ; Johansson, Maria ; Andersson, Carlaxel
in: Dalton Transactions (Print Edition), issue: 23, pages: 4187-4192

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1999     |    DOI: https://doi.org/10.1039/a908077e