Mikael Rørdam Andersen

Mikael Rørdam Andersen

Guest Professor

DTU BIOENGINEERING
Department of Biotechnology and Biomedicine

Technical University of Denmark

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2019
 

Genetic engineering approaches to improve post-translational modification of biopharmaceuticals in different production platforms

Amann, Thomas ; Schmieder, Valerie ; Kildegaard, Helene Faustrup ; Borth, Nicole ; Andersen, Mikael Rørdam
in: Biotechnology and Bioengineering, vol: 116, issue: 10, pages: 2778-2796

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1002/bit.27101

 

Reprogramming AA catabolism in CHO cells with CRISPR/Cas9 genome editing improves cell growth and reduces byproduct secretion

Ley, Daniel ; Pereira, Sara ; Pedersen, Lasse Ebdrup ; Arnsdorf, Johnny ; Hefzi, Hooman ; Davy, Anne Mathilde ; Kwang Ha, Tae ; Wulff, Tune ; Kildegaard, Helene Faustrup ; Andersen, Mikael Rørdam
in: Metabolic Engineering, vol: 56, pages: 120-129

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.ymben.2019.09.005

  PDF

Resistance gene-directed genome mining of 50 Aspergillus species

Kjærbølling, Inge ; Vesth, Tammi ; Andersen, Mikael R.
in: mSystems, vol: 4, issue: 4

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1128/mSystems.00085-19

 

Systematic Evaluation of Site-Specific Recombinant Gene Expression for Programmable Mammalian Cell Engineering

Pristovšek, Nuša ; Nallapareddy, Saranya ; Grav, Lise Marie ; Hefzi, Hooman ; Lewis, Nathan E. ; Rugbjerg, Peter ; Hansen, Henning Gram ; Lee, Gyun Min ; Andersen, Mikael Rørdam ; Kildegaard, Helene Faustrup
in: ACS Synthetic Biology, vol: 8, issue: 4, pages: 758-774

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1021/acssynbio.8b00453

2018
  PDF

Linking secondary metabolites to gene clusters through genome sequencing of six diverse Aspergillus species

Kjærbølling, Inge ; Vesth, Tammi C. ; Frisvad, Jens C. ; Nybo, Jane L. ; Theobald, Sebastian ; Kuo, Alan ; Bowyer, Paul ; Matsuda, Yudai ; Mondo, Stephen ; Lyhne, Ellen K. ; Kogle, Martin E. ; Clum, Alicia ; Lipzen, Anna ; Salamov, Asaf ; Ngan, Chew Yee ; Daum, Chris ; Chiniquy, Jennifer ; Barry, Kerrie ; LaButti, Kurt ; Haridas, Sajeet ; Simmons, Blake A. ; Magnuson, Jon K. ; Mortensen, Uffe H. ; Larsen, Thomas O. ; Grigoriev, Igor V. ; Baker, Scott E. ; Andersen, Mikael R.
in: Proceedings of the National Academy of Sciences of the United States of America, vol: 115, issue: 4, pages: E753-E761

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1073/pnas.1715954115

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A community-driven reconstruction of the Aspergillus niger metabolic network

Brandl, Julian ; Aguilar-Pontes, Maria Victoria ; Schäpe, Paul ; Nørregaard, Anders ; Arvas, Mikko ; Ram, Arthur F. J. ; Meyer, Vera ; Tsang, Adrian ; de Vries, Ronald P. ; Andersen, Mikael Rørdam
in: Fungal Biology and Biotechnology, vol: 5

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1186/s40694-018-0060-7

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An Online Compendium of CHO RNA-Seq Data Allows Identification of CHO Cell Line-specific Transcriptomic Signatures

Singh, Ankita ; Kildegaard, Helene F. ; Andersen, Mikael R.
in: Biotechnology Journal, vol: 13, issue: 10

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1002/biot.201800070

  PDF

Antibody Cross-Reactivity in Antivenom Research

Ledsgaard, Line ; Jenkins, Timothy P ; Davidsen, Kristian ; Krause, Kamille Elvstrøm ; Martos-Esteban, Andrea ; Engmark, Mikael ; Andersen, Mikael Rørdam ; Lund, Ole ; Laustsen, Andreas Hougaard
in: Toxins, vol: 10, issue: 10

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.3390/toxins10100393

  PDF

Application of a curated genome-scale metabolic model of CHO DG44 to an industrial fed-batch process

Calmels, Cyrielle ; McCann, Andréa ; Malphettes, Laetitia ; Andersen, Mikael Rørdam
in: Metabolic Engineering, vol: 51, pages: 9-19

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1016/j.ymben.2018.09.009