Alina Vitaliyivna Kulakova

Alina Vitaliyivna Kulakova

Postdoc

DTU CHEMISTRY
Department of Chemistry

Physical and Biophysical Chemnistry: Protein and X-ray Crystallography

Technical University of Denmark

Kemitorvet

Building 206, room 208

2800 Kgs. Lyngby

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2020
 

Advancing Therapeutic Protein Discovery and Development through Comprehensive Computational and Biophysical Characterization

Gentiluomo, Lorenzo ; Svilenov, Hristo L ; Augustijn, Dillen ; El Bialy, Inas ; Greco, Maria Laura ; Vitaliyivna Kulakova, Alina ; Indrakumar, Sowmya ; Mahapatra, Sujata ; Morales, Marcello Martinez ; Pohl, Christin ; Roche, Aisling ; Tosstorff, Andreas ; Curtis, Robin ; Derrick, Jeremy P ; Nørgaard, Allan ; Khan, Tarik A ; Peters, Günther H.J. ; Pluen, Alain ; Rinnan, Åsmund ; Streicher, Werner W ; van der Walle, Christopher F ; Uddin, Shahid ; Winter, Gerhard ; Roessner, Dierk ; Harris, Pernille ; Frieß, Wolfgang
in: Molecular Pharmaceutics, vol: 17, issue: 2, pages: 426-440

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1021/acs.molpharmaceut.9b00852

 

Orthogonal techniques to study the effect of pH, sucrose and arginine salts on monoclonal antibody physical stability and aggregation during long-term storage

Svilenov, Hristo L. ; Kulakova, Alina ; Zalar, Matja ; Golovanov, Alexander P. ; Harris, Pernille ; Winter, Gerhard
in: Journal of Pharmaceutical Sciences, vol: 109, issue: 1, pages: 584-594

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1016/j.xphs.2019.10.065

  PDF

Small angle X-ray scattering and molecular dynamic simulations provide molecular insight for stability of recombinant human transferrin

Kulakova, Alina ; Indrakumar, Sowmya ; Sønderby, Pernille ; Gentiluomo, Lorenzo ; Streicher, Werner ; Roessner, Dierk ; Frieß, Wolfgang ; Peters, Günther H.J. ; Harris, Pernille
in: Journal of Structural Biology: X, vol: 4

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1016/j.yjsbx.2019.100017

2019
 

Application of interpretable artificial neural networks to early monoclonal antibodies development

Gentiluomo, Lorenzo ; Roessner, Dierk ; Augustijn, Dillen ; Svilenov, Hristo ; Kulakova, Alina ; Mahapatra, Sujata ; Winter, Gerhard ; Streicher, Werner ; Rinnan, Åsmund ; Peters, Günther H.J. ; Harris, Pernille ; Frieß, Wolfgang
in: European Journal of Pharmaceutics and Biopharmaceutics, vol: 141, pages: 81-89

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.ejpb.2019.05.017

 

Novel Non-linear Curve Fitting to Resolve Protein Unfolding Transitions in Intrinsic Fluorescence Differential Scanning Fluorimetry

Augustijn, Dillen ; Mahapatra, Sujata ; Streicher, Werner ; Svilenov, Hristo ; Kulakova, Alina ; Pohl, Christin ; Rinnan, Åsmund
in: European Journal of Pharmaceutics and Biopharmaceutics, vol: 142, pages: 506-517

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.ejpb.2019.06.001