Thomas Sicheritz-Pontén

Thomas Sicheritz-Pontén


Department of Bio and Health Informatics

Technical University of Denmark


Building 208, room 021

2800 Kgs. Lyngby

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Dr. Thomas Sicheritz-Ponten fil.dr, has a background in Bioinformatics and Molecular Evolution from Uppsala University, Sweden and has been working in the genome/metagenome sequencing field for over 20 years, starting 1996 when he built the bioinformatics infrastructure for the first published Scandinavian genome project. He was also the first bioinformatics PhD to be examined from Uppsala University.

He is collecting different samples from all-over the world and develops new tools that will address many of the unique challenges of metagenomics data sets. The majority of his projects are based on at least one of following three simple question: Who is in there? What are they doing? How are they doing it?

He works in collaborations with scientific groups with widely different interests and experience in bioinformatics from all over the world and his group is constantly exploring new areas within the world utilising NGS, Omics, Big Data and AI.  He collects samples from all branches of the tree of life from all over the world and engages in expeditions across the globe including India, the Amazon rainforest, Australian bush, Arabian desert, Greenland wilderness, Polar seas and the Southeast Asian rainforests.

A major focus is animal (everything from human, koalas, vultures to vampire bats) microbiomes and hologenomes and the development of novel strategies for microbiome analysis. He is also involved in the Center for Genomic Epidemiology for the analysis of metagenomic samples from sewage, urine, feces, lungs, blood for surveillance and diagnostics and outbreak detection and visualisation e.g. global disease tracking using long-distance flights

A substantial part of his research is to support the biotech industry and find novel solution to industrial challenges. That ranges from using ‘omics tools to identify the pathways responsible for the production of the natural colours in insects and plants to improving the taste of wine by identifying microbial communities and their importance during anaerobic fermentation and aerobic processes.