Marlene Danner Dalgaard

Marlene Danner Dalgaard

Senior Researcher

DTU BIOINFORMATICS
Department of Bio and Health Informatics

DTU Bioinformatics Employees
Quantitative and Systems Genomics

Technical University of Denmark

Kemitorvet

Building 208, room 159

2800 Kgs. Lyngby

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2018
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Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells article

Winge, Sofia Boeg ; Dalgaard, Marlene Danner ; Belling, Kirstine G. ; Jensen, Jacob Malte ; Nielsen, John Erik ; Aksglaede, Lise ; Schierup, Mikkel Heide ; Brunak, Søren ; Skakkebæk, Niels Erik ; Juul, Anders ; Rajpert-De Meyts, Ewa ; Almstrup, Kristian
in: Cell Death & Disease (ISSN: 2041-4889), vol: 9, issue: 6, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1038/s41419-018-0671-1

 

Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation

Winge, Sofia Boeg ; Dalgaard, Marlene Danner ; Jensen, Jacob M. ; Graem, Niels ; Schierup, Mikkel H. ; Juul, Anders ; Rajpert-De Meyts, Ewa ; Almstrup, Kristian
in: Human Molecular Genetics (ISSN: 0964-6906), vol: 27, issue: 3, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1093/hmg/ddx411

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Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

Kristensen, David Møbjerg ; Desdoits-Lethimonier, Christèle ; Mackey, Abigail L ; Dalgaard, Marlene Danner ; De Masi, Federico ; Munkbøl, Cecilie Hurup ; Styrishave, Bjarne ; Antignac, Jean-Philippe ; Le Bizec, Bruno ; Platel, Christian ; Hay-Schmidt, Anders ; Jensen, Tina Kold ; Lesné, Laurianne ; Mazaud-Guittot, Séverine ; Kristiansen, Karsten ; Brunak, Søren ; Kjær, Michael ; Juul, Anders Christian ; Jégou, Bernard
in: Proceedings of the National Academy of Sciences of the United States of America (ISSN: 0027-8424), vol: 115, issue: 17, pages: E715-E724, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1073/pnas.1715035115

 

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism (vol 115, pg E715, 2018)

Kristensen, David Mobjerg ; Desdoits-Lethimonier, Christéle ; Mackey, Abigail L. ; Dalgaard, Marlene Danner ; De Masi, Federico ; Munkbol, Cecilie Hurup ; Styrishave, Bjarne ; Antignac, Jean-Philippe ; Le Bizec, Bruno ; Platel, Christian ; Hay-Schmidt, Anders ; Jensen, Tina Kold ; Lesne, Laurianne ; Mazaud-Guittot, SVerine ; Kristiansen, Karsten ; Brunak, Søren ; Kjær, Michael ; Juul, Anders Christian ; Jegou, Bernard
in: Proceedings of the National Academy of Sciences of the United States of America (ISSN: 0027-8424), vol: 115, issue: 17, pages: E4143-E4143, 2018

Type: Comment/debate

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1073/pnas.1805313115

2017
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Novel genes involved in pathophysiology of gonadotropin-dependent adrenal tumors in mice

Doroszko, Milena ; Chrusciel, Marcin ; Belling, Kirstine González-Izarzugaza ; Vuorenoja, Susanna ; Dalgaard, Marlene Danner ; Leffers, Henrik ; Nielsen, Henrik Bjørn ; Huhtaniemi, Ilpo ; Toppari, Jorma ; Rahman, Nafis A
in: Molecular and Cellular Endocrinology (ISSN: 0303-7207), vol: 444, pages: 9-18, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1016/j.mce.2017.01.036

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Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity

Belling, Kirstine González-Izarzugaza ; Russo, Francesco ; Jensen, Anders Boeck ; Dalgaard, Marlene Danner ; Westergaard, David ; Rajpert-De Meyts, Ewa ; Skakkebæk, Niels E. ; Juul, Anders Christian ; Brunak, Søren
in: Human Molecular Genetics (ISSN: 0964-6906), vol: 26, issue: 7, pages: 1219-1229, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1093/hmg/ddx014

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Obesity is associated with depot-specific alterations in adipocyte DNA methylation and gene expression

Sonne, Si Brask ; Yadav, Rachita ; Yin, Guangliang ; Dalgaard, Marlene Danner ; Myrmel, Lene Secher ; Gupta, Ramneek ; Wang, Jun ; Madsen, Lise ; Kajimura, Shingo ; Kristiansen, Karsten
in: Adipocyte (Philadelphia) (ISSN: 2162-3945), vol: 6, issue: 2, pages: 124-133, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1080/21623945.2017.1320002

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High throughput resistance profiling of Plasmodium falciparum infections based on custom dual indexing and Illumina next generation sequencing-technology

Nag, Sidsel ; Dalgaard, Marlene Danner ; Kofoed, Poul-Erik ; Ursing, Johan ; Crespo, Marina ; Andersen, Lee O'Brien ; Aarestrup, Frank Møller ; Lund, Ole ; Alifrangis, Michael
in: Scientific Reports (ISSN: 2045-2322), vol: 7, issue: 1, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1038/s41598-017-02724-x

 

Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor

Wang, Zhaoming ; McGlynn, Katherine A. ; Rajpert-De Meyts, Ewa ; Bishop, D. Timothy ; Chung, Charles C. ; Dalgaard, Marlene Danner ; Greene, Mark H. ; Gupta, Ramneek ; Grotmol, Tom ; Haugen, Trine B. ; Karlsson, Robert ; Litchfield, Kevin ; Mitra, Nandita ; Nielsen, Kasper ; Pyle, Louise C. ; Schwartz, Stephen M. ; Thorsson, Vésteinn ; Vardhanabhuti, Saran ; Wiklund, Fredrik ; Turnbull, Clare ; Chanock, Stephen J. ; Kanetsky, Peter A. ; Nathanson, Katherine L.
in: Nature Genetics (ISSN: 1061-4036), vol: 49, issue: 7, pages: 1141-1147, 2017

Type: Letter (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1038/ng.3879

 

Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents

Lottrup, Grete ; Belling, Kirstine González-Izarzugaza ; Leffers, Henrik ; Nielsen, John E. ; Dalgaard, Marlene Danner ; Juul, Anders ; Skakkebæk, Niels E. ; Brunak, Søren ; Rajpert-De Meyts, Ewa
in: Molecular Human Reproduction (ISSN: 1360-9947), vol: 23, issue: 5, pages: 339-354, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1093/molehr/gax012