Fredrik Melander

Fredrik Melander

Researcher

DTU HEALTH TECH
Department of Health Technology

Technical University of Denmark

Produktionstorvet

Building 423, room 204

2800 Kgs. Lyngby

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2019
 

Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo

Johnsen, Kasper Bendix ; Bak, Martin ; Melander, Fredrik ; Thomsen, Maj Schneider ; Burkhart, Annette ; Kempen, Paul Joseph ; Andresen, Thomas Lars ; Moos, Torben
in: Journal of Controlled Release, vol: 295, pages: 237-249

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.jconrel.2019.01.005

 

The combination of biologic-loaded liposomes and retinal ganglion cell transplant rescues retinal function in an NMDA toxicity model

Eriksen, Anne Zebitz ; Oswald, Julia ; Kempen, Paul J. ; Melander, Fredrik ; Young, Michael ; Baranov, Petr Y. ; Urquhart, Andrew J.
in: Investigative Ophthalmology & Visual Science, vol: 60, issue: 9
Presented at:
ARVO 2019 Annual Meeting

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2019

2018
  PDF

Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles

Johnsen, Kasper Bendix ; Bak, Martin ; Kempen, Paul Joseph ; Melander, Fredrik ; Burkhart, Annette ; Thomsen, Maj Schneider ; Nielsen, Morten Schallburg ; Moos, Torben ; Andresen, Thomas Lars
in: Theranostics, vol: 8, issue: 12, pages: 3416-3436

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.7150/thno.25228

 

Development of dual corticosteroid loaded functionalized liposomes for enhanced drug delivery to the retinal endothelium

Arta, Anthoula ; Melander, Fredrik ; Andresen, Thomas Lars ; Urquhart, Andrew
in: Investigative Ophthalmology & Visual Science, vol: 59, issue: 9
Presented at:
ARVO Annual Meeting 2018

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2018

  PDF

Endothelial Protein C–Targeting Liposomes Show Enhanced Uptake and Improved Therapeutic Efficacy in Human Retinal Endothelial Cells

Arta, Anthoula ; Eriksen, Anne Z. ; Melander, Fredrik ; Kempen, Paul ; Larsen, Michael ; Andresen, Thomas L. ; Urquhart, Andrew J.
in: Investigative Ophthalmology & Visual Science, vol: 59, issue: 5, pages: 2119-2132

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1167/iovs.18-23800

  PDF

Multifarious Biologic Loaded Liposomes that Stimulate the Mammalian Target of Rapamycin Signaling Pathway Show Retina Neuroprotection after Retina Damage

Eriksen, Anne Zebitz ; Eliasen, Rasmus ; Oswald, Julia ; Kempen, Paul J. ; Melander, Fredrik ; Andresen, Thomas Lars ; Young, Michael ; Baranov, Petr ; Urquhart, Andrew J.
in: A C S Nano, vol: 12, issue: 8, pages: 7497-7508

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1021/acsnano.8b00596

 

Theranostic Imaging May Vaccinate against the Therapeutic Benefit of Long Circulating PEGylated Liposomes and Change Cargo Pharmacokinetics

Børresen, Betina ; Henriksen, Jonas R. ; Clergeaud, Gael ; Jørgensen, Jennifer S. ; Melander, Fredrik ; Elema, Dennis R. ; Szebeni, Janos ; Engelholm, Svend Aage ; Kristensen, Annemarie T. ; Kjær, Andreas ; Andresen, Thomas L. ; Hansen, Anders E.
in: ACS Nano, vol: 12, issue: 11, pages: 11386-11398

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1021/acsnano.8b06266

2017
 

Modulating antibody affinity towards the transferrin receptor to increase brain uptake of anti-transferrin receptor antibody targeted gold nanoparticles

Johnsen, Kasper Bendix ; Bak, Martin ; Melander, Fredrik ; Burkhart, Annette ; Kempen, Paul ; Andresen, Thomas Lars ; Moos, Torben
in: American Journal of Hematology, vol: 92, issue: 8, pages: E198-E198

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2017

 

Revisiting the use of sPLA2-sensitive liposomes in cancer therapy

Pourhassan, Houman ; Clergeaud Veiga, Gael ; Hansen, Anders Elias ; Østrem, Ragnhild Garborg ; Fliedner, Frederikke P. ; Melander, Fredrik ; Nielsen, Ole L. ; O'Sullivan, Ciara K. ; Kjær, Andreas ; Andresen, Thomas Lars
in: Journal of Controlled Release, vol: 261, pages: 163-173

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1016/j.jconrel.2017.06.024

  PDF

18F-FDG PET/CT-based early treatment response evaluation of nanoparticle-assisted photothermal cancer therapy

Norregaard, Kamilla ; Jørgensen, Jesper T. ; Simón, Marina ; Melander, Fredrik ; Kristensen, Lotte K. ; Bendix, Pól M. ; Andresen, Thomas Lars ; Oddershede, Lene B. ; Kjær, Andreas
in: P L o S One, vol: 12, issue: 5

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.1371/journal.pone.0177997