Jay Keasling

Jay Keasling

Scientific Director

DTU BIOSUSTAIN
Novo Nordisk Foundation Center for Biosustainability

Technical University of Denmark

Kogle Allé 6

Building Cederhuset, room xx

2970 Hørsholm

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2020
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Evolution-guided engineering of small-molecule biosensors

Snoek, Tim ; Chaberski, Evan Kirk ; Ambri, Francesca ; Kol, Stefan ; Bjørn, Sara P ; Pang, Bo ; Barajas, Jesus F ; Welner, Ditte Hededam ; Jensen, Michael Krogh ; Keasling, Jay D.
in: Nucleic acids research, vol: 48, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1093/nar/gkz954

 

High-resolution scanning of optimal biosensor reporter promoters in yeast

Ambri, Francesca ; D'ambrosio, Vasil ; Di Blasi, Roberto ; Maury, Jerome ; Baallal Jacobsen, Simo Abdessamad ; McCloskey, Douglas ; Jensen, Michael Krogh ; Keasling, Jay D.
in: ACS Synthetic Biology, vol: 9, issue: 2, pages: 218-226

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1021/acssynbio.9b00333

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Insights into the Mechanism of Phenylacetate Decarboxylase (PhdB), a Toluene-Producing Glycyl Radical Enzyme

Rodrigues, Andria V. ; Tantillo, Dean J. ; Mukhopadhyay, Aindrila ; Keasling, Jay ; Beller, Harry R.
in: ChemBioChem, vol: 21, issue: 5, pages: 663-671

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1002/cbic.201900560

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Leveraging host metabolism for bisdemethoxycurcumin production in Pseudomonas putida

Incha, Matthew R. ; Thompson, Mitchell G. ; Blake-Hedges, Jacquelyn M. ; Liu, Yuzhong ; Pearson, Allison N. ; Schmidt, Matthias ; Gin, Jennifer W. ; Petzold, Christopher J. ; Deutschbauer, Adam M. ; Keasling, Jay D.
in: Metabolic Engineering Communications, vol: 10

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1016/j.mec.2019.e00119

 

Optimising the biosynthesis of oxygenated and acetylated Taxol precursors in Saccharomyces cerevisiae using advanced bioprocessing strategies

Walls, Laura E. ; Malci, Koray ; Nowrouzi, Behnaz ; Li, Rachel ; d'Espaux, Leo ; Wong, Jeff ; Dennis, Jonathan A. ; Semiao, Andrea J C ; Wallace, Stephen ; Martinez, José L. ; Keasling, Jay D. ; Rios-Solis, Leonardo
in: Biotechnology and Bioengineering

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2020     |    DOI: https://doi.org/10.1002/bit.27569

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Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast

Jakočiūnas, Tadas ; Klitgaard, Andreas K. ; Kontou, Eftychia Eva ; Nielsen, Julie Bang ; Thomsen, Emil ; Romero Suarez, David ; Blin, Kai ; Petzold, Christopher J. ; Gin, Jennifer W. ; Tong, Yaojun ; Gotfredsen, Charlotte Held ; Charusanti, Pep ; Frandsen, Rasmus J. N. ; Weber, Tilmann ; Lee, Sang Yup ; Jensen, Michael Krogh ; Keasling, Jay D.
in: Synthetic and Systems Biotechnology, vol: 5, issue: 1, pages: 11-18

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1016/j.synbio.2020.01.004

 

Structural Mechanism of Regioselectivity in an Unusual Bacterial Acyl-CoA Dehydrogenase

Blake-Hedges, Jacquelyn M. ; Pereira, Jose Henrique ; Cruz-Morales, Pablo ; Thompson, Mitchell G. ; Barajas, Jesus F. ; Chen, Jeffrey ; Krishna, Rohith N. ; Chan, Leanne Jade G. ; Nimlos, Danika ; Alonso-Martinez, Catalina ; Baidoo, Edward E.K. ; Chen, Yan ; Gin, Jennifer W. ; Katz, Leonard ; Petzold, Christopher J. ; Adams, Paul D. ; Keasling, Jay D.
in: Journal of the American Chemical Society, vol: 142, issue: 2, pages: 835-846

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1021/jacs.9b09187

2019
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A High-Throughput Mass Spectrometric Enzyme Activity Assay Enabling the Discovery of Cytochrome P450 Biocatalysts

de Rond, Tristan ; Gao, Jian ; Zargar, Amin ; de Raad, Markus ; Cunha, Jack ; Northen, Trent R. ; Keasling, Jay D.
in: Angewandte Chemie International Edition, vol: 58, issue: 30, pages: 10114-10119

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1002/anie.201901782

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A rapid methods development workflow for high-throughput quantitative proteomic applications

Chen, Yan ; Vu, Jonathan ; Thompson, Mitchell G. ; Sharpless, William A. ; Chan, Leanne Jade G. ; Gin, Jennifer W. ; Keasling, Jay D. ; Adams, Paul D. ; Petzold, Christopher J.
in: PLOS ONE, vol: 14, issue: 2

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1371/journal.pone.0211582

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Automated "cells-To-Peptides" Sample Preparation Workflow for High-Throughput, Quantitative Proteomic Assays of Microbes

Chen, Yan ; Guenther, Joel M. ; Gin, Jennifer W. ; Chan, Leanne Jade G. ; Costello, Zak ; Ogorzalek, Tadeusz L. ; Tran, Huu M. ; Blake-Hedges, Jacquelyn M. ; Keasling, Jay D. ; Adams, Paul D. ; García Martín, Héctor ; Hillson, Nathan J. ; Petzold, Christopher J.
in: Journal of Proteome Research, vol: 18, issue: 10, pages: 3752-3761

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1021/acs.jproteome.9b00455