Sine Reker Hadrup

Sine Reker Hadrup

Head of Sections, Professor

DTU HEALTH TECH
Department of Health Technology

Technical University of Denmark

Kemitorvet

Building 204, room 154

2800 Kgs. Lyngby

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2020
 

Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition: impact on clinical outcome

de Lima, Vinicius Araujo B. ; Borch, Annie ; Hansen, Morten ; Draghi, Arianna ; Spanggaard, Iben ; Rohrberg, Kristoffer ; Hadrup, Sine Reker ; Lassen, Ulrik ; Svane, Inge Marie
in: Cytotherapy, vol: 22, pages: 204-213

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.1016/j.jcyt.2020.01.010

 

Optimization in Detection of Antigen-Specific T Cells Through Differentially Labeled MHC Multimers

Pedersen, Natasja Wulff ; Laske, Karoline ; Maurer, Dominik ; Welters, Marij ; Walter, Steffen ; Gouttefangeas, Cécile ; Hadrup, Sine Reker
in: Cytometry. Part A

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2020     |    DOI: https://doi.org/10.1002/cyto.a.23942

  PDF

Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift Mutations

Hansen, Ulla Kring ; Ramskov, Sofie ; Bjerregaard, Anne-Mette ; Borch, Annie ; Andersen, Rikke ; Draghi, Arianna ; Donia, Marco ; Bentzen, Amalie Kai ; Marquard, Andrea Marion ; Szallasi, Zoltan Imre ; Eklund, Aron Charles ; Svane, Inge Marie ; Hadrup, Sine Reker
in: Frontiers in Immunology, vol: 11

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2020     |    DOI: https://doi.org/10.3389/fimmu.2020.00373

2019
  PDF

CD8+ T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens

Pedersen, Natasja Wulff ; Holm, Anja ; Kristensen, Nikolaj Pagh ; Bjerregaard, Anne-Mette ; Bentzen, Amalie Kai ; Marquard, Andrea Marion ; Tamhane, Tripti ; Burgdorf, Kristoffer Sølvsten ; Ullum, Henrik ; Jennum, Poul ; Knudsen, Stine ; Hadrup, Sine Reker ; Kornum, Birgitte Rahbek
in: Nature Communications, vol: 10, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1038/s41467-019-08774-1

 

Dissecting the T cell receptor interactions governing recognition of peptide-MHC complexes

Bentzen, Amalie Kai ; Such, Lina ; Jensen, K. K. ; Marquard, Andrea Marion ; Jessen, Leon Eyrich ; Miller, N. J. ; Church, C. D. ; Lyngaa, Rikke Birgitte ; Koelle, D. M. ; Becker, J. C. ; Linnemann, C. ; Schumacher, T. N. M. ; Marcatili, Paolo ; Nghiem, P. ; Nielsen, M. ; Hadrup, Sine Reker
in: European Journal of Immunology, vol: 49, issue: Suppl. 3 SI, pages: 1787-1787
Presented at:
17th International Congress of Immunology

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2019

 

Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells

Saini, Sunil Kumar ; Tamhane, Tripti ; Anjanappa, Raghavendra ; Saikia, Ankur ; Ramskov, Sofie ; Donia, Marco ; Svane, Inge Marie ; Jakobsen, Søren Nyboe ; Garcia-Alai, Maria ; Zacharias, Martin ; Meijers, Rob ; Springer, Sebastian ; Hadrup, Sine Reker
in: Science Immunology, vol: 4, issue: 37

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1126/sciimmunol.aau9039

 

HLA-C restricted neoepitopes contribute significantly to the immune recognition of cancer

Ramskov, Sofie ; Hansen, Kring U. ; Saini, Kumar S. ; Sturm, T. ; Borch, Annie ; Bjerregaard, Anne-Mette ; Bentzen, Kai A. ; Marquard, Marion A. ; Donia, M. ; Andersen, R. ; Draghi, A. ; Reading, J. ; Vogler, I. ; Derhovanessian, E. ; Lassen, U. ; Sahin, U. ; Swanton, A. C. ; Quezada, S. ; Svane, I. M. ; Fugmann, T. ; Hadrup, Reker S.
in: European Journal of Immunology, vol: 49, issue: Suppl. 3 SI, pages: 387-387
Presented at:
17th International Congress of Immunology

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2019

 

Large-scale identification and transcriptional characterisation of auto-reactive CD8 T cells in multiple sclerosis

Pedersen, Natasja Wulff ; Kristensen, Nikolaj Pagh ; Bentzen, Amalie Kai ; von Essen, M. R. ; Selleberg, F. T. ; Hadrup, Sine Reker
in: European Journal of Immunology, vol: 49, issue: Suppl. 3 SI, pages: 388-389
Presented at:
17th International Congress of Immunology

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019

 

Lipid Nanoparticles for Delivery of Therapeutic RNA Oligonucleotides

Moss, Keith Henry ; Popova, Petya ; Hadrup, Sine Reker ; Astakhova, Kira ; Taskova, Maria
in: Molecular Pharmaceutics, vol: 16, issue: 6, pages: 2265-2277

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1021/acs.molpharmaceut.8b01290

 

Pilot study on the feasibility, safety and immunogenicity of a personalized neoantigen-targeted immunotherapy (NeoPepVac) in combination with anti-PD-1 or anti-PD-L1 in advanced solid tumors

Moerk, S.K. ; Donia, M. ; Kringelum, J.V. ; Bogenrieder, T. ; Rønø, B. ; Sorensen, A.B. ; Draghi, A. ; Bol, K F ; Petersen, N.V. ; Kadivar, M. ; Hernandez, S S ; Hadrup, S. Reker ; Andreasen, L.V. ; Christensen, D. ; Andersen, P.L. ; Svane, I.M.
in: Annals of Oncology, vol: 30, issue: Supplement_11
Presented at:
ESMO Immuno-Oncology Congress 2019

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1093/annonc/mdz451.019