Maher  Abou Hachem

Maher Abou Hachem

Professor MSO

DTU BIOENGINEERING
Institut for Bioteknologi og Biomedicin

PCET-Protein Glycoscience and Biotechnology

Danmarks Tekniske Universitet

Søltofts Plads

Bygning 224, rum 222

2800 Kgs. Lyngby

Tlf.
Tlf.
Fax 45 88 63 07
E-mail maha@bio.dtu.dk
ORCID 0000-0001-8250-1842

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2019
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A novel starch-binding laccase from the wheat pathogen Zymoseptoria tritici highlights the functional diversity of ascomycete laccases

Haddad Momeni, Majid ; Bollella, Paolo ; Ortiz, Roberto ; Thormann, Esben ; Gorton, Lo ; Abou Hachem, Maher
in: B M C Biotechnology, vol: 19

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1186/s12896-019-0552-4

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Substrate preference of an ABC importer corresponds to selective growth on β-(1,6)-galactosides in Bifidobacterium animalis subsp. lactis

Theilmann, Mia Christine ; Fredslund, Folmer ; Svensson, Birte ; Lo Leggio, Leila ; Abou Hachem, Maher
in: Journal of Biological Chemistry, vol: 294, issue: 31, pages: 11701-11711

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1074/jbc.RA119.008843

 

1H, 13C and 15N backbone and side-chain assignment of a carbohydrate binding module from a xylanase from Roseburia intestinalis

Madland, Eva ; Kitaoku, Yoshihito ; Sætrom, Gerd Inger ; Leth, Maria Louise ; Ejby, Morten ; Abou Hachem, Maher ; Aachmann, Finn Lillelund
in: Biomolecular N M R Assignments, vol: 13, issue: 1, pages: 55-58

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1007/s12104-018-9850-3

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The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans

La Rosa, Sabina Leanti ; Leth, Maria Louise ; Michalak, Leszek ; Hansen, Morten Ejby ; Pudlo, Nicholas A. ; Glowacki, Robert ; Pereira, Gabriel ; Workman, Christopher T. ; Arntzen, Magnus ; Pope, Phillip B. ; Martens, Eric C. ; Hachem, Maher Abou ; Westereng, Bjørge
in: Nature Communications, vol: 10, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1038/s41467-019-08812-y

 

Two binding proteins of the ABC transporter that confers growth of Bifidobacterium animalis subsp. lactis ATCC27673 on β-mannan possess distinct manno-oligosaccharide-binding profiles

Ejby, M. ; Guskov, A. ; Pichler, Michael Jakob ; Zanten, G. C. ; Schoof, Erwin ; Saburi, W. ; Slotboom, D. J. ; Abou Hachem, Maher
in: Molecular Microbiology, vol: 112, issue: 1, pages: 114-130

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1111/mmi.14257

2018
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Differential bacterial capture and transport preferences facilitate co-growth on dietary xylan in the human gut

Leth, Maria Louise ; Ejby, Morten ; Workman, Christopher ; Ewald, David Adrian ; Pedersen, Signe Schultz ; Sternberg, Claus ; Bahl, Martin Iain ; Licht, Tine Rask ; Aachmann, Finn Lillelund ; Westereng, Bjørge ; Abou Hachem, Maher
in: Nature Microbiology

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: https://doi.org/10.1038/s41564-018-0132-8

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Effect of alginate size, mannuronic/guluronic acid content and pH on particle size, thermodynamics and composition of complexes with β-lactoglobulin

Stender, Emil G.P. ; Khan, Sanaullah ; Ipsen, Richard ; Madsen, Finn ; Hägglund, Per ; Hachem, Maher Abou ; Almdal, Kristoffer ; Westh, Peter ; Svensson, Birte
in: Food Hydrocolloids, vol: 75, pages: 157-163

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: https://doi.org/10.1016/j.foodhyd.2017.09.001

2017
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An extracellular cell-attached pullulanase confers branched α-glucan utilization in human gut Lactobacillus acidophilus

Møller, Marie Sofie ; Goh, Yong Jun ; Rasmussen, Kasper Bøwig ; Cypryk, Wojciech ; Celebioglu, Hasan Ufuk ; Klaenhammer, Todd R ; Svensson, Birte ; Abou Hachem, Maher
in: Applied and Environmental Microbiology, vol: 83, issue: 10

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: https://doi.org/10.1128/AEM.00402-17

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Data regarding the growth of Lactobacillus acidophilus NCFM on different carbohydrates and recombinant production of elongation factor G and pyruvate kinase

Celebioglu, Hasan Ufuk ; Olesen, Sita Vaag ; Prehn, Kennie ; Lahtinen, Sampo J ; Pedersen, Susanne Brix ; Abou Hachem, Maher ; Svensson, Birte
in: Data in Brief, vol: 14, pages: 118-122

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: https://doi.org/10.1016/j.dib.2017.07.021

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Discovery of α-L-arabinopyranosidases from human gut microbiome expands the diversity within glycoside hydrolase family 42

Viborg, Alexander Holm ; Katayama, Takane ; Arakawa, Takatoshi ; Abou Hachem, Maher ; Lo Leggio, Leila ; Kitaoka, Motomitsu ; Svensson, Birte ; Fushinobu, Shinya
in: Journal of Biological Chemistry

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: https://doi.org/10.1074/jbc.M117.792598

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Effect of repeat unit structure and molecular mass of lactic acid bacteria hetero-exopolysaccharides on binding to milk proteins

Birch, Johnny ; HarÐarson, HörÐur Kári ; Khan, Sanaullah ; Van Calsteren, Marie-Rose ; Ipsen, Richard ; Garrigues, Christel ; Almdal, Kristoffer ; Abou Hachem, Maher ; Svensson, Birte
in: Carbohydrate Polymers, vol: 177, pages: 406-414

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: https://doi.org/10.1016/j.carbpol.2017.08.055

 

Fungal secretomics to probe the biological functions of lytic polysaccharide monooxygenases

Berrin, Jean-Guy ; Rosso, Marie-Noëlle ; Abou Hachem, Maher
in: CARBOHYDRATE RESEARCH, vol: 448, pages: 155-160

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: https://doi.org/10.1016/j.carres.2017.05.010

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Lactobacillus acidophilus Metabolizes Dietary Plant Glucosides and Externalizes Their Bioactive Phytochemicals

Theilmann, Mia Christine ; Goh, Yong Jun ; Nielsen, Kristian Fog ; Klaenhammer, Todd R. ; Barrangou, Rodolphe ; Abou Hachem, Maher ; Martens, Eric (Editor) ; McFall-Ngai, Margaret J. (Editor)
in: mBio (Online), vol: 8, issue: 6, pages: e01421-17

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: https://doi.org/10.1128/mBio.01421-17

 

Mucin- and carbohydrate-stimulated adhesion and subproteome changes of the probiotic bacterium Lactobacillus acidophilus NCFM

Celebioglu, Hasan Ufuk ; Olesen, Sita Vaag ; Prehn, Kennie ; Lahtinen, Sampo J. ; Pedersen, Susanne Brix ; Abou Hachem, Maher ; Svensson, Birte
in: Journal of Proteomics, vol: 163, pages: 102-110

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: https://doi.org/10.1016/j.jprot.2017.05.015

2016
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An ATP Binding Cassette Transporter Mediates the Uptake of α-(1,6)-Linked Dietary Oligosaccharides in Bifidobacterium and Correlates with Competitive Growth on These Substrates

Hansen, Morten Ejby ; Fredslund, Folmer ; Andersen, Joakim Mark ; Žagar, Andreja Vujičić ; Henriksen, Jonas Rosager ; Andresen, Thomas Lars ; Svensson, Birte ; Slotboom, Dirk Jan ; Abou Hachem, Maher
in: Journal of Biological Chemistry, vol: 291, issue: 38, pages: 20220-20231

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: https://doi.org/10.1074/jbc.M116.746529

 

An efficient arabinoxylan-debranching α-l-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site

Wilkens, Casper ; Andersen, Susan ; Petersen, Bent O. ; Li, An ; Busse-Wicher, Marta ; Birch, Johnny ; Cockburn, Darrell ; Nakai, Hiroyuki ; Christensen, Hans Erik Mølager ; Kragelund, Birthe B. ; Dupree, Paul ; McCleary, Barry ; Hindsgaul, Ole ; Abou Hachem, Maher ; Svensson, Birte
in: Applied Microbiology and Biotechnology, vol: 100, issue: 14, pages: 6265-6277

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: https://doi.org/10.1007/s00253-016-7417-8

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A snapshot into ATP-binding cassette transporter mediated glycan uptake in probiotic bifidobacteria

Hansen, Morten Ejby ; Theilmann, Mia Christine ; Saburi, Wataru ; Fredslund, Folmer ; Svensson, Birte ; Lo Leggio, Leila ; Licht, Tine Rask ; Slotboom, Dirk Jan ; Abou Hachem, Maher
Presented at:
The 11th Danish Conference on Biotechnology and Molecular Biology: Glycobiology and Carbohydrate Biotechnology.

Type: Conference abstract for conference (Peer reviewed)

Status: Published     |    År: 2016

 

Differential proteome and cellular adhesion analyses of the probiotic bacterium Lactobacillus acidophilus NCFM grown on raffinose - an emerging prebiotic

Celebioglu, Hasan Ufuk ; Hansen, Morten Ejby ; Majumder, Avishek ; Købler, Carsten ; Jun Goh, Yong ; Thorsen, Kristian ; Schmidt, Bjarne Gregers ; O'Flaherty, Sarah ; Abou Hachem, Maher ; Lahtinen, Sampo J. ; Jacobsen, Susanne ; Klaenhammer, Todd R. ; Pedersen, Susanne Brix ; Mølhave, Kristian ; Svensson, Birte
in: Proteomics, vol: 16, issue: 9, pages: 1361-1375

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: https://doi.org/10.1002/pmic.201500212

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Fungal lytic polysaccharide monooxygenases bind starch and β-cyclodextrin similarly to amylolytic hydrolases

Nekiunaite, Laura ; Isaksen, Trine ; Vaaje-Kolstad, Gustav ; Abou Hachem, Maher
in: F E B S Letters, vol: 590, issue: 16, pages: 2737-2747

Type: Letter (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: https://doi.org/10.1002/1873-3468.12293

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FgLPMO9A from Fusarium graminearum cleaves xyloglucan independently of the backbone substitution pattern

Nekiunaite, Laura ; Petrović, Dejan M. ; Westereng, Bjørge ; Vaaje-Kolstad, Gustav ; Abou Hachem, Maher ; Várnai, Anikó ; Eijsink, Vincent G.H.
in: F E B S Letters, vol: 590, issue: 19, pages: 3346-3356

Type: Letter (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: https://doi.org/10.1002/1873-3468.12385

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Lytic polysaccharide monooxygenases and other oxidative enzymes are abundantly secreted by Aspergillus nidulans grown on different starches

Nekiunaite, Laura ; Arntzen, Magnus Ø. ; Svensson, Birte ; Vaaje-Kolstad, Gustav ; Abou Hachem, Maher
in: Biotechnology for Biofuels, vol: 9, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: https://doi.org/10.1186/s13068-016-0604-0

 

Plant α-glucan phosphatases SEX4 and LSF2 display different affinity for amylopectin and amylose

Wilkens, Casper ; Auger, Kyle D. ; Anderson, Nolan T. ; Meekins, David A. ; Raththagala, Madushi ; Abou Hachem, Maher ; Payne, Christina M. ; Gentry, Matthew S. ; Svensson, Birte
in: FEBS Letters, vol: 590, issue: 1, pages: 118-128

Type: Journal article (Peer reviewed)

Status: E-pub ahead of print     |    År: 2016     |    DOI: https://doi.org/10.1002/1873-3468.12027

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Structural and Mechanical Properties of Thin Films of Bovine Submaxillary Mucin versus Porcine Gastric Mucin on a Hydrophobic Surface in Aqueous Solutions

Madsen, Jan Busk ; Sotres, Javier ; Pakkanen, Kirsi I. ; Efler, Petr ; Svensson, Birte ; Abou Hachem, Maher ; Arnebrant, Thomas ; Lee, Seunghwan
in: Langmuir, vol: 32, issue: 38, pages: 9687–9696

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: https://doi.org/10.1021/acs.langmuir.6b02057

2015
 

Analysis of Surface Binding Sites (SBS) within GH62, GH13, and GH77

Wilkens, Casper ; Cockburn, Darrell ; Andersen, Susan ; Ole Petersen, Bent ; Ruzanski, Christian ; A. Field, Robert ; Hindsgaul, Ole ; Nakai, Hiroyuki ; McCleary, Barry ; M. Smith, Alison ; Abou Hachem, Maher ; Svensson, Birte
in: Journal of Applied Glycoscience, vol: 62, issue: 3, pages: 87-93

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2015     |    DOI: https://doi.org/10.5458/jag.jag.jag-2015_006

 

A Simplified Chromatographic Approach to Purify Commercially Available Bovine Submaxillary Mucins (BSM)

Madsen, Jan Busk ; Pakkanen, Kirsi I. ; Duelund, Lars ; Svensson, Birte ; Abou Hachem, Maher ; Lee, Seunghwan
in: Preparative Biochemistry and Biotechnology, vol: 45, pages: 84-99

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2015     |    DOI: https://doi.org/10.1080/10826068.2014.887583

 

Characterising interactions between alginates of different sizes and beta-lactoglobulin

Stender, Emil G. P. ; Khan, Sanaullah ; Mäkinen, Outi E. ; Almdal, Kristoffer ; Westh, Peter ; Ibsen, Richard ; Abou Hachem, Maher ; Svensson, Birte
in: Protein Science, vol: 24, issue: S1, pages: 303-303

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    År: 2015     |    DOI: https://doi.org/10.1002/pro.2823

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Crystal Structure of Barley Limit Dextrinase-Limit Dextrinase Inhibitor (LD-LDI) Complex Reveals Insights into Mechanism and Diversity of Cereal Type Inhibitors

Møller, Marie Sofie ; Vester-Christensen, Malene Bech ; Jensen, Johanne M. ; Abou Hachem, Maher ; Henriksen, Anette ; Svensson, Birte
in: Journal of Biological Chemistry, vol: 290, issue: 20, pages: 12614-12629

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2015     |    DOI: https://doi.org/10.1074/jbc.M115.642777

 

Epistatic Mutations And Unpredictable Phenotypes In Pseudomonas Aeruginosa

Andresen, Eva Kammer ; Abou Hachem, Maher ; Jelsbak, Lars
part of: The Danish Microbiological Society Annual Congress 2015, pages: 49-49, 2015, Copenhagen
Presented at:
The Danish Microbiological Society Annual Congress 2015

Type: Conference abstract in proceedings (Peer reviewed)

Status: Published     |    År: 2015

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Lotus japonicus flowers are defended by a cyanogenic β-glucosidase with highly restricted expression to essential reproductive organs

Lai, Daniela ; Pičmanová, Martina ; Abou Hachem, Maher ; Motawia, Mohammed Saddik ; Olsen, Carl Erik ; Møller, Birger Lindberg ; Rook, Fred ; Takos, Adam M.
in: PLANT MOLECULAR BIOLOGY, vol: 89, issue: 1-2, pages: 21-34

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2015     |    DOI: https://doi.org/10.1007/s11103-015-0348-4

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Oligosaccharide and Substrate Binding in the Starch Debranching Enzyme Barley Limit Dextrinase

Møller, Marie Sofie ; Windahl, Michael Skovbo ; Sim, Lyann ; Bøjstrup, Marie ; Abou Hachem, Maher ; Hindsgaul, Ole ; Palcic, Monica ; Svensson, Birte ; Henriksen, Anette
in: Journal of Molecular Biology, vol: 427, issue: 6, Part B, pages: 1263-1277

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2015     |    DOI: https://doi.org/10.1016/j.jmb.2014.12.019

 

Proteolytic Degradation of Bovine Submaxillary Mucin (BSM) and Its Impact on Adsorption and Lubrication at a Hydrophobic Surface

Madsen, Jan Busk ; Svensson, Birte ; Abou Hachem, Maher ; Lee, Seunghwan
in: Langmuir, vol: 31, issue: 30, pages: 8303-8309

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2015     |    DOI: https://doi.org/10.1021/acs.langmuir.5b01281

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The GH5 1,4-β-mannanase from Bifidobacterium animalis subsp. lactis Bl-04 possesses a low-affinity mannan-binding module and highlights the diversity of mannanolytic enzymes

Morrill, Johan ; Kulcinskaja, Evelina ; Sulewska, Anna Maria ; Lahtinen, Sampo ; Stålbrand, Henrik ; Svensson, Birte ; Abou Hachem, Maher
in: BMC Biochemistry, vol: 16, issue: 26

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2015     |    DOI: https://doi.org/10.1186/s12858-015-0055-4

2014
 

Analysis of surface binding sites (SBSs) in carbohydrate active enzymes with focus on glycoside hydrolase families 13 and 77

Cockburn, Darrell ; Wilkens, Casper ; Ruzanski, Christian ; Andersen, Susan ; Willum Nielsen, Jonas ; Smith, Alison M. ; Field, Robert A. ; Willemoes, Martin ; Abou Hachem, Maher ; Svensson, Birte
in: Biologia, vol: 69, issue: 6, pages: 705-712

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2014     |    DOI: https://doi.org/10.2478/s11756-014-0373-9

 

A β1-6/β1-3 galactosidase from B ifidobacterium animalis subsp. lactis Bl-04 gives insight into sub-specificities of β-galactoside catabolism within B ifidobacterium

Viborg, Alexander Holm ; Fredslund, Folmer ; Katayama, Takane ; Nielsen, Stinne Kirketerp ; Svensson, Birte ; Kitaoka, Motomitsu ; Leggio, Leila Lo ; Abou Hachem, Maher
in: Molecular Microbiology, vol: 94, issue: 5, pages: 1024–1040

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2014     |    DOI: https://doi.org/10.1111/mmi.12815

 

Distinct substrate specificities of three glycoside hydrolase family 42 β-galactosidases from Bifidobacterium longum subsp. infantis ATCC 15697

Viborg, Alexander Holm ; Katayama, Takane ; Abou Hachem, Maher ; Andersen, Mathias Christian Franch ; Nishimoto, Mamoru ; Clausen, Mads Hartvig ; Urashima, Tadasu ; Svensson, Birte ; Kitaoka, Motomitsu
in: Glycobiology, vol: 24, issue: 2, pages: 208-216

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2014     |    DOI: https://doi.org/10.1093/glycob/cwt104

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Interaction of Lactobacillus acidophilus NCFM grown on different carbohydrates with human intestinal epithelial cells: Adhesion Properties and roles of S-layer Proteins

Celebioglu, Hasan Ufuk ; Lahtinen, Sampo J ; Pedersen, Susanne Brix ; Abou Hachem, Maher ; Svensson, Birte
Presented at:
11th international Symposium on Lactic Acid Bacteria

Type: Conference abstract for conference (Peer reviewed)

Status: Published     |    År: 2014

 

Recent insight in α-glucan metabolism in probiotic bacteria

Møller, Marie Sofie ; Goh, Yong Jun ; Viborg, Alexander Holm ; Andersen, Joakim Mark ; Klaenhammer, Todd R. ; Svensson, Birte ; Abou Hachem, Maher
in: Biologia, vol: 69, issue: 6, pages: 713-721

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2014     |    DOI: https://doi.org/10.2478/s11756-014-0367-7

 

The evolutionary appearance of non-cyanogenic hydroxynitrile glucosides in the Lotus genus is accompanied by the substrate specialization of paralogous beta-glucosidases resulting from a crucial amino acid substitution

Lai, Daniela ; Abou Hachem, Maher ; Robson, Fran ; Olsen, Carl Erik ; Wang, Trevor L. ; Møller, Birger Lindberg ; Takos, Adam M. ; Rook, Fred
in: Plant Journal, vol: 79, issue: 2, pages: 299-311

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2014     |    DOI: https://doi.org/10.1111/tpj.12561

2013
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Adhesion and Proteome Analyses of Lactobacillus acidophilus NCFM grown with the potential Prebiotic Raffinose

Celebioglu, Hasan Ufuk ; Hansen, Morten Ejby ; Majumder, Avishek ; Dabene, Valentina ; Legaard, Camilla Bergholz ; Havmøller, Ingeborg Lund ; Thorsen, K. ; Lahtinen, Sampo J. ; Abou Hachem, Maher ; Jacobsen, Susanne ; Svensson, Birte
part of: Proceedings of the International Scientific Conference on Probiotics and Prebiotics, 2014
Presented at:
International Scientific Conference on Probiotics and Prebiotics 2013

Type: Conference abstract in proceedings (Peer reviewed)

Status: Published     |    År: 2013

 

Arabidopsis thaliana AMY3 Is a Unique Redox-regulated Chloroplastic α-Amylase

Seung, David ; Thalmann, Matthias ; Sparla, Francesca ; Abou Hachem, Maher ; Lee, Sang Kyu ; Issakidis-Bourguet, Emmanuelle ; Svensson, Birte ; Zeeman, Samuel C. ; Santelia, Diana
in: Journal of Biological Chemistry, vol: 288, issue: 47, pages: 33620-33633

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2013     |    DOI: https://doi.org/10.1074/jbc.M113.514794

 

A snapshot into the metabolism of isomalto-oligosaccharides in probiotic bacteria

Abou Hachem, Maher ; Møller, Marie Sofie ; Andersen, Joakim Mark ; Fredslund, Folmer ; Majumder, Avishek ; Nakai, Hiroyuki ; Leggio, Leila lo ; Goh, Yong-Jun ; Barrangou, R. ; Klaenhammer, Todd R. ; Svensson, Birte
in: Journal of Applied Glycoscience, vol: 60, issue: 2, pages: 95-100

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2013     |    DOI: https://doi.org/10.5458/jag.jag.JAG-2012_022

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Biotribological properties of bovine submaxillary mucin (BSM) at the hydrophobic interface

Madsen, Jan Busk ; Nikogeorgos, Nikolaos ; Abou Hachem, Maher ; Svensson, Birte ; Lee, Seunghwan
in: European Cells & Materials, vol: 26, issue: Suppl. 6, pages: 111
Presented at:
4th International Symposium on Surfaces and Interfaces for Biomaterials

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    År: 2013

 

In vitro growth of four individual human gut bacteria on oligosaccharides produced by chemoenzymatic synthesis.

Vigsnæs, Louise Kristine ; Nakai, Hiroyuki ; Hemmingsen, Lene ; Andersen, Joakim Mark ; Lahtinen, Sampo J ; Rasmussen, Louise Enggaard ; Abou Hachem, Maher ; Petersen, Bent O. ; Duus, Jens Øllgaard ; Meyer, Anne S. ; Licht, Tine Rask ; Svensson, Birte
in: Food & Function, vol: 4, issue: 5, pages: 784-793

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2013     |    DOI: https://doi.org/10.1039/C3FO30357H

 

Kinetic analysis of inhibition of glucoamylase and active site mutants via chemoselective oxime immobilization of acarbose on SPR chip surfaces

Sauer, Jørgen ; Abou Hachem, Maher ; Svensson, Birte ; Jensen, Knud J. ; Thygesen, Mikkel
in: CARBOHYDRATE RESEARCH, vol: 375, pages: 21-28

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2013     |    DOI: https://doi.org/10.1016/j.carres.2013.04.012

 

Recent insight into oligosaccharide uptake and metabolism in probiotic bacteria

Abou Hachem, Maher ; Andersen, Joakim Mark ; Barrangou, Rodolphe ; Møller, Marie Sofie ; Fredslund, Folmer ; Majumder, Avishek ; Hansen, Morten Ejby ; Lahtinen, Sampo J. ; Jacobsen, Susanne ; Lo Leggio, Leila ; Goh, Yong Jun ; Klaenhammer, Todd R. ; Svensson, Birte
in: Biocatalysis and Biotransformation, vol: 31, issue: 4, pages: 226-235
Presented at:
10th Carbohydrate Bioengineering Meeting

Type: Conference article (Peer reviewed)

Status: Published     |    År: 2013     |    DOI: https://doi.org/10.3109/10242422.2013.828048

 

Structural basis for arabinoxylo‐oligosaccharide capture by the probiotic Bifidobacterium animalis subsp. lactis Bl‐04

Hansen, Morten Ejby ; Fredslund, Folmer ; Vujicic‐Zagar, Andreja ; Svensson, Birte ; Slotboom, Dirk Jan ; Abou Hachem, Maher
in: Molecular Microbiology, vol: 90, issue: 5, pages: 1100-1112

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2013     |    DOI: https://doi.org/10.1111/mmi.12419

 

Surface binding sites (SBSs), mechanism and regulation of enzymes degrading amylopectin and α-limit dextrins.

Møller, Marie Sofie ; Cockburn, Darrell ; Nielsen, Jonas W. ; Jensen, Johanne M. ; Vester-Christensen, Malene B. ; Nielsen, Morten Munch ; Andersen, Joakim Mark ; Wilkens, Casper ; Rannes, Julie Bille ; Hägglund, Per ; Henriksen, Anette ; Abou Hachem, Maher ; Willemoës, Martin ; Svensson, Birte
in: Journal of Applied Glycoscience, vol: 60, issue: 2, pages: 101-109

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2013     |    DOI: https://doi.org/10.5458/jag.jag.JAG-2012_023

  PDF

Transcriptional analysis of oligosaccharide utilization by Bifidobacterium lactis Bl-04

Andersen, Joakim Mark ; Barrangou, Rodolphe ; Abou Hachem, Maher ; Lahtinen, Sampo J. ; Goh, Yong Jun ; Svensson, Birte ; Klaenhammer, Todd R
in: BMC Genomics, vol: 14, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2013     |    DOI: https://doi.org/10.1186/1471-2164-14-312

2012
 

Degradation of the starch components amylopectin and amylose by barley α-amylase 1: Role of surface binding site 2

Nielsen, Jonas Willum ; Kramhøft, Birte ; Bozonnet, Sophie ; Abou Hachem, Maher ; Stipp, Susan Louise Svane ; Svensson, Birte ; Willemoes, Martin
in: Archives of Biochemistry and Biophysics, vol: 528, issue: 1, pages: 1-6

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2012     |    DOI: https://doi.org/10.1016/j.abb.2012.08.005

 

Enzymology and Structure of the GH13_31 Glucan 1,6-α-Glucosidase That Confers Isomaltooligosaccharide Utilization in the Probiotic Lactobacillus acidophilus NCFM

Møller, Marie Sofie ; Fredslund, Folmer ; Majumder, Avishek ; Nakai, Hiroyuki ; Poulsen, Jens-Christian Navarro ; Lo Leggio, Leila ; Svensson, Birte ; Abou Hachem, Maher
in: Journal of Bacteriology, vol: 194, issue: 16, pages: 4249-4259

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2012     |    DOI: https://doi.org/10.1128/JB.00622-12

 

Isothermal titration calorimetry and surface plasmon resonance allow quantifying substrate binding to different binding sites of Bacillus subtilis xylanase

Cuyvers, Sven ; Dornez, Emmie ; Abou Hachem, Maher ; Svensson, Birte ; Hothorn, Michael ; Chory, Joanne ; Delcour, Jan A. ; Courtin, Christophe M.
in: Analytical Biochemistry, vol: 420, issue: 1, pages: 90-92

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2012     |    DOI: https://doi.org/10.1016/j.ab.2011.09.005

 

Raffinose family oligosaccharide utilisation by probiotic bacteria: insight into substrate recognition, molecular architecture and diversity of GH36 alpha-galactosidases

Abou Hachem, Maher ; Fredslund, Folmer ; Andersen, Joakim Mark ; Larsen, Rene Jonsgaard ; Majumder, Avishek ; Hansen, Morten Ejby ; van Zanten, Gabriella Christina ; Lahtinen, S. J. ; Barrangou, R. ; Klaenhammer, T. ; Jacobsen, S. ; Coutinho, P. M. ; Lo Leggio, Leila ; Svensson, Birte
in: Biocatalysis and Biotransformation, vol: 30, issue: 3, pages: 316-325

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2012     |    DOI: https://doi.org/10.3109/10242422.2012.674717

  PDF

Structure of the starch-debranching enzyme barley limit dextrinase reveals homology of the N-terminal domain to CBM21

Møller, Marie Sofie ; Abou Hachem, Maher ; Svensson, Birte ; Henriksen, Anette
in: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, vol: 68, issue: Pt 9, pages: 1008-1012

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2012     |    DOI: https://doi.org/10.1107/S1744309112031004

  PDF

Transcriptional Analysis of Prebiotic Uptake and Catabolism by Lactobacillus acidophilus NCFM.

Andersen, Joakim Mark ; Barrangou, Rodolphe ; Abou Hachem, Maher ; Lahtinen, Sampo J ; Goh, Yong-Jun ; Svensson, Birte ; Klaenhammer, Todd R
in: P L o S One, vol: 7, issue: 9, pages: e44409

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2012

2011
 

Crystal Structure of α-Galactosidase from Lactobacillus acidophilus NCFM: Insight into Tetramer Formation and Substrate Binding

Fredslund, Folmer ; Abou Hachem, Maher ; Larsen, Rene Jonsgaard ; Sørensen, Pernille Gerd ; Coutinho, Pedro M. ; Lo Leggio, Leila ; Svensson, Birte
in: Journal of Molecular Biology, vol: 412, issue: 3, pages: 466-480

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2011     |    DOI: https://doi.org/10.1016/j.jmb.2011.07.057

 

Efficient secretory expression of functional barley limit dextrinase inhibitor by high cell-density fermentation of Pichia pastoris

Jensen, Johanne Mørch ; Vester-Christensen, Malene Bech ; Møller, Marie Sofie ; Bønsager, Birgit Christine ; Christensen, Hans Erik Mølager ; Abou Hachem, Maher ; Svensson, Birte
in: Protein Expression and Purification, vol: 79, issue: 2, pages: 217-222

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2011     |    DOI: https://doi.org/10.1016/j.pep.2011.04.009

 

Enzymatic synthesis of β-xylosyl-oligosaccharides by transxylosylation using two beta-xylosidases of glycoside hydrolase family 3 from Aspergillus nidulans FGSC A4

Dilokpimol, Adiphol ; Nakai, Hiroyuki ; Gotfredsen, Charlotte Held ; Appeldoorn, Maaike ; Baumann, Martin ; Nakai, Natsuko ; Schols, Henk A. ; Abou Hachem, Maher ; Svensson, Birte
in: Carbohydrate Research, vol: 346, issue: 3, pages: 421-429

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2011     |    DOI: https://doi.org/10.1016/j.carres.2010.12.010

  PDF

Expression of enzymatically inactive wasp venom phospholipase A1 in Pichia pastoris

Borodina, Irina ; Jensen, Bettina M. ; Wagner, Tim ; Abou Hachem, Maher ; Søndergaard, Ib ; Poulsen, Lars Kærgaard
Presented at:
6th Danish Conference on Biotechnology and Molecular Biology

Type: Conference abstract for conference (Peer reviewed)

Status: Published     |    År: 2011

  PDF

Expression of Enzymatically Inactive Wasp Venom Phospholipase A1 in Pichia pastoris

Borodina, Irina ; Jensen, Bettina M. ; Wagner, Tim ; Abou Hachem, Maher ; Søndergaard, Ib ; Poulsen, Lars Kærgaard
in: P L o S One, vol: 6, issue: 6, pages: e21267

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2011     |    DOI: https://doi.org/10.1371/journal.pone.0021267

 

Spanning ’integrated omics’ and green chemistry to discover prebiotic oligosaccharides

Svensson, Birte ; Majumder, Avishek ; Hansen, Morten Ejby ; Andersen, Joakim Mark ; van Zanten, Gabriella Christina ; Barangou, R. ; Lahtinen, J. ; Klaenhammer, T.R. ; Abou Hachem, Maher ; Jacobsen, Susanne
Presented at:
LMC Congress 2011

Type: Conference abstract for conference

Status: Published     |    År: 2011

 

Starch‐binding domains in the CBM45 family – low‐affinity domains from glucan, water dikinase and α‐amylase involved in plastidial starch metabolism

Glaring, Mikkel Andreas ; Baumann, Martin ; Abou Hachem, Maher ; Nakai, Hiroyuki ; Nakai, Natsuko ; Santelia, Diana ; Sigurskjold, Bent W. ; Zeeman, Samuel C. ; Blennow, Andreas ; Svensson, Birte
in: F E B S Journal, vol: 278, issue: 7, pages: 1175-1185

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2011     |    DOI: https://doi.org/10.1111/j.1742-4658.2011.08043.x

 

The relationship between probiotics and prebiotic carbohydrates. Chemoenzymatic synthesis and differential proteome analysis

Nakai, Hiroyuki ; Majumder, Avishek ; Dilokpimol, Adiphol ; Hansen, Morten Ejby ; Abou Hachem, Maher ; Lahtinen, S. (Invited author) ; Jacobsen, Susanne ; Svensson, Birte
Presented at:
4th Conference on Biocatalysis in the Food and Drink Industries

Type: Conference abstract for conference     |     Invited contribution

Status: Published     |    År: 2011

 

Transcriptional and functional analysis of galactooligosaccharide uptake by lacS in Lactobacillus acidophilus

Andersen, Joakim Mark ; Barrangou, Rodolphe ; Abou Hachem, Maher ; Lahtinen, Sampo ; Goh, Yong Jun ; Svensson, Birte ; Klaenhammer, Todd R
in: Proceedings of the National Academy of Sciences of the United States of America, vol: 108, issue: 43, pages: 17785-17790

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2011     |    DOI: https://doi.org/10.1073/pnas.1114152108

2010
 

Aspergillus nidulans α-galactosidase of glycoside hydrolase family 36 catalyses the formation of α-galacto-oligosaccharides by transglycosylation

Nakai, Hiroyuki ; Baumann, Martin ; Petersen, B. O. ; Westphal, Y. ; Abou Hachem, Maher ; Dilokpimol, Adiphol ; Duus, Jens Øllgaard ; Schols, H. A. ; Svensson, Birte
in: F E B S Journal, vol: 277, issue: 17, pages: 3538-3551

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2010     |    DOI: https://doi.org/10.1111/j.1742-4658.2010.07763.x

 

Barley limit dextrinase and limit dextrinase inhibitor

Svensson, Birte ; Vester-Christensen, Malene Bech ; Jensen, Johanne Mørch (Invited author) ; Henriksen, A. (Invited author) ; Hägglund, Per ; Abou Hachem, Maher
Presented at:
4th Symposium on the Alpha-Amylase Family

Type: Poster     |     Invited contribution

Status: Published     |    År: 2010

 

Barley limit dextrinase structure and its implications for enzyme activity

Vester-Christensen, Malene Bech ; Abou Hachem, Maher ; Henriksen, A. ; Svensson, Birte
Presented at:
Plant Polysaccharide and Applied Glycoscience Workshop 2010

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

Chemoenzymatic synthesis of novel oligosaccharides by reverse phosphorolysis

Nakai, Hiroyuki ; Baumann, M.J ; Petersen, B.O. ; Westphal, Y. ; Mannerstedt,, K. ; Abou Hachem, Maher ; Dilokpimol, Adiphol ; Lahtinen, S.J. ; Schols, H.A. ; Duus, J.Ø. ; Svensson, Birte
Presented at:
Plant Polysaccharide and Applied Glycoscience Workshop 2010

Type: Poster

Status: Published     |    År: 2010

 

Crystal structure, carbohydrate- and protein-protein interactions of barley limit dextrinase, limit dextrinase inhibitor and thioredoxin

Svensson, Birte ; Jensen, J.M. ; Vester-Christensen, Malene Bech ; Hägglund, Per ; Henriksen, A. ; Abou Hachem, Maher
Presented at:
2010 AACC International Annual Meeting

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

Crystal structure of an essential enzyme in seed starch degradation - barley limit dextrinase in complex with cyclodextrins

Vester-Christensen, Malene Bech ; Abou Hachem, Maher ; Svensson, Birte ; Henriksen, A.
in: Journal of Molecular Biology, vol: 403, issue: 5, pages: 739-750

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2010     |    DOI: https://doi.org/10.1016/j.jmb.2010.09.031

 

Efficient chemoenzymatic oligosaccharide synthesis by reverse phosphorolysis using cellobiose phosphorylase and cellodextrin phosphorylase from Clostridium thermocellum

Nakai, Hiroyuki ; Abou Hachem, Maher ; Petersen, Bent O. ; Westphal, Yvonne ; Mannerstedt, Karin ; Baumann, Martin ; Dilokpimol, Adiphol ; Schols, Henk A. ; Duus, Jens Øllgaard ; Svensson, Birte
in: Biochimie, vol: 92, issue: 12, pages: 1818-1826

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2010     |    DOI: https://doi.org/10.1016/j.biochi.2010.07.013

 

Enzymatic synthesis of α-1,6-galactosyl oligosaccharides by transglycosy-lation of GH36 α-galactosidase from Aspergillus nidulans FGSC A4

Nakai, Hiroyuki ; Baumann, Martin ; Petersen, B.O. ; Westphal, Y. ; Dilokpimol, Adiphol ; Abou Hachem, Maher ; Schols, H.A. ; Duus, Jens Øllgaard ; Svensson, Birte
Presented at:
25th International Carbohydrate Symposium

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

Exploring the transglycosylation activity of barley limit dextrinase

Vester-Christensen,, M.B ; Jensen, J.M. ; Abou Hachem, Maher ; Rejzek, M. ; Dedola, S. ; Field, R.A. ; Svensson, Birte
Presented at:
25th International Carbohydrate Symposium

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

Expression and charcterisation of starch binding domains from Carbohydrate Binding Module family 45

Glaring, M.A. ; Baumann, M.J. ; Andersen, J.M. ; Nakai, Hiroyuki ; Nakai, Natsuko ; Vidova, B. ; Abou Hachem, Maher ; Blennow, A. ; Svensson, Birte
Presented at:
Annual Plant Biotech Denmark Meeting 2010

Type: Poster

Status: Published     |    År: 2010

 

Genetic screening identifies cyanogenesis deficient mutants of Lotus japonicus and reveals enzymatic specificity in hydroxynitrile glucoside metabolism

Takos, A. ; Lai, D. ; Mikkelsen, L. ; Abou Hachem, Maher ; Shelton, D. ; Bak, S. ; Saddik Motawia, M. ; Olsen, C.E. ; Lindberg Møller, B. ; Wang, T.L. ; Martin, C. ; Rook, F.
Presented at:
Annual Plant Biotech Denmark Meeting 2010

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

Genetic Screening Identifies Cyanogenesis-Deficient Mutants of Lotus japonicus and Reveals Enzymatic Specificity in Hydroxynitrile Glucoside Metabolism

Takos, A. ; Lai, D. ; Mikkelsen, L. ; Abou Hachem, Maher ; Shelton, D. ; Motawia, M.S. ; Olsen, C.E. ; Wang, T.L. ; Martin, C. ; Rook, F.
in: Plant Cell, vol: 22, issue: 5, pages: 1605-1619

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2010     |    DOI: https://doi.org/10.1105/tpc.109.073502

 

Investigating the interaction between recombinant barley limit dextrinase and its endogenous inhibitor

Jensen, Johanne Mørch ; Vester-Christensen, M.B. ; Abou Hachem, Maher ; Hägglund, Per ; Svensson, Birte
Presented at:
Plant Polysaccharide and Applied Glycoscience Workshop 2010

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

Isomaltooligosaccharide catabolism in the probiotic bacterium Lactobacillus acidophilus NCFM mediated by 1,6-α-glucosidases from GH13_31

Møller, Marie Sofie ; Sørensen, P. G. ; Abou Hachem, Maher ; Svensson, Birte
Presented at:
4th Symposium on the Alpha-Amylase Family

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

limit dextrinase inhibitor uses a different mode of action than homologous α-amylse inhibitors

Jensen, J.M ; Vester-Christensen, Malene Bech ; Abou Hachem, Maher ; Svensson, Birte
Presented at:
4th Symposium on the Alpha-Amylase Family

Type: Poster

Status: Published     |    År: 2010

 

New insight into structure/function relationships in plant alpha-amylase family GH13 members.

Seo, Eun-Seong ; Andersen, Joakim Mark ; Nielsen, Morten Munch ; Vester-Christensen, Malene Bech ; Christiansen, Camilla ; Jensen, Johanne Mørch ; Mótyán, J. A. ; Janeček, Š. ; Haser, R. ; Glaring, Mikkel Andreas ; Blennow, A. ; Kandra, L. ; Gyémánt, G. ; Aghajari, N. ; Abou Hachem, Maher ; Svensson, Birte
in: Journal of Applied Glycoscience, vol: 57, issue: 2, pages: 157-162

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2010

 

Prebiotic oligosaccharides. Chemoenzymatic procedures for efficient synthesis and proteomics identification of the molecular basis of prebiotic effects in probiotic bacteria

Svensson, Birte ; Nakai, Hiroyuki ; Majumder, Avishek ; Hansen, Morten Ejby ; Petersen, B.O. (Invited author) ; Westphal, Y. (Invited author) ; Mannerstedt, K. (Invited author) ; Dilokpimol, Adiphol ; Lahtinen, S.J. (Invited author) ; Jacobsen, Susanne ; Schols, H.A. (Invited author) ; Duus, Jens Øllgaard ; Abou Hachem, Maher
Presented at:
25th International Carbohydrate Symposium

Type: Conference abstract for conference     |     Invited contribution

Status: Published     |    År: 2010

 

Production, purification, characterisation and protein-protein interaction measurements of barley limit dextrinase inhibitor

Svensson, Birte ; Vester-Christensen, Malene Bech ; Jensen, Johanne Mørch ; Henriksen, A. ; Hägglund, Per ; Andersen, J. M. ; Møller, Marie Sofie ; Abou Hachem, Maher
Presented at:
Plant Polysaccharide and Applied Glycoscience Workshop 2010

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

Rational engineering of Lactobacillus acidophilus NCFM maltose phosphorylase into either trehalose or kojibiose dual specificity phosphorylase

Nakai, Hiroyuki ; Petersen, B.O. ; Westphal, Y. ; Dilokpimol, Adiphol ; Abou Hachem, Maher ; Duus, Jens Øllgaard ; Schols, H.A. ; Svensson, Birte
in: Protein Engineering Design and Selection (Print), vol: 23, issue: 10, pages: 781-787

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2010     |    DOI: https://doi.org/10.1093/protein/gzq055

 

Secretory expression of functional barley limit dextrinase by Pichia pastoris using high cell-density fermentation

Vester-Christensen, Malene Bech ; Abou Hachem, Maher ; Næsted, Henrik ; Svensson, Birte
in: Protein Expression and Purification, vol: 69, issue: 1, pages: 112-119

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2010     |    DOI: https://doi.org/10.1016/j.pep.2009.08.016

 

Starch binding domains from CBM20 and CBM45 occurring in enzymes regulating starch metabolism display substantially lower binding affinities than counterparts from strictly starch-degrading enzymes

Glaring, M.A ; Baumann, M.J. ; Christiansen, C. ; Viksø-Nielsen,:, A. ; Nakai, Hiroyuki ; Nakai, Natsuko ; Vidova, B. ; Sigurskjold, B.W. ; Blennow, A. ; Svensson, Birte ; Abou Hachem, Maher
Presented at:
4th Symposium on the Alpha-Amylase Family

Type: Poster

Status: Published     |    År: 2010

 

Structure-function relationship investigations and protein engineering of carbohydrate surface binding sites of barley α-amylase

Andersen, J. M. ; Nielsen, Morten Munch ; Møller, Marie Sofie ; Abou Hachem, Maher ; Blennow, A. ; Svensson, Birte
Presented at:
Plant Polysaccharide and Applied Glycoscience Workshop 2010

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

Structure of α-galactosidase from Lactobacillus acidophilus NCFM: insight into tetramer formation and substrate binding

Fredslund, Folmer ; Abou Hachem, Maher ; Larsen, Rene Jonsgaard (Invited author) ; Sørensen, P.G. (Invited author) ; lo Leggio, L. (Invited author) ; Svensson, Birte
Presented at:
The 19th CoLuAa Conference

Type: Conference abstract for conference     |     Invited contribution

Status: Published     |    År: 2010

 

Surface binding sites in amylolytic enzymes

Wilkens, Casper ; Cockburn, Darrell ; Abou Hachem, Maher ; Vester-Christensen, Malene Bech
Presented at:
4th Symposium on the Alpha-Amylase Family

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

The effects of four selected synbiotics on community and activity of the intestinal microbiota using a simulated colon model

van Zanten, Gabriella Christina ; Mäkeläinen, H. ; Forssten, S. ; Bandsholm, O. ; Knudsen, Anne ; Lawther, M. ; Blennow, A. ; Abou Hachem, Maher ; Lahtinen, S. ; Svensson, Birte ; Jespersen, L.
Presented at:
International Scientific Conference on Probiotics and Prebiotics 2010

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

The GH36 α-galactosidases from Lactobacillus acidophilus NCFM is substrate inhibited and reveals the involvement of an active site cysteine in substrate binding

Abou Hachem, Maher ; Larsen, J.J. ; Sørensen, P.G. ; Fredslund, Folmer ; Leggio, L. Lo ; Svensson, Birte
Presented at:
25th International Carbohydrate Symposium

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

The structure of a GH13_31 α-glucosidase from the probiotic bacterium Lactobacillus acidophilus NCFM

Svensson, Birte ; Fredslund, Folmer ; Møller, Marie Sofie ; Leggio, L. Lo ; Abou Hachem, Maher
Presented at:
4th Symposium on the Alpha-Amylase Family

Type: Conference abstract for conference

Status: Published     |    År: 2010

 

Transcriptional analysis of prebiotic utilization by Lactobacillus acidophilus NCFM

Andersen, Joakim Mark ; Barrangou, R. ; Abou Hachem, Maher ; Svensson, Birte ; Goh, Y. ; Klaenhammer, T.R.
Presented at:
American Society for Microbiology 110th General Meeting

Type: Conference abstract for conference

Status: Published     |    År: 2010

2009
 

A CBM20 low-affinity starch-binding domain from glucan, water dikinase

Christiansen, Camilla ; Abou Hachem, Maher ; Glaring, M.A. ; Vikso-Nielsen, A. ; Sigurskjold, B.W. ; Svensson, Birte ; Blennow, A.
in: FEBS Letters, vol: 583, issue: 7, pages: 1159-1163

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2009     |    DOI: https://doi.org/10.1016/j.febslet.2009.02.045

 

The carbohydrate-binding module family 20-diversity, structure, and function

Christiansen, Camilla ; Abou Hachem, Maher ; Janecek, S. ; Vikso-Nielsen, A. ; Blennow, A. ; Svensson, Birte
in: F E B S Journal, vol: 276, issue: 18, pages: 5006-5029

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2009     |    DOI: https://doi.org/10.1111/j.1742-4658.2009.07221.x

 

The maltodextrin transport system and metabolism in Lactobacillus acidophilus NCFM and production of novel alpha-glucosides through reverse phosphorolysis by maltose phosphorylase

Nakai, Hiroyuki ; Baumann, Martin ; Petersen, B.O. ; Westphal, Y. ; Schols, H. ; Dilokpimol, Adiphol ; Abou Hachem, Maher ; Lahtinen, S.J. ; Duus, Jens Øllgaard ; Svensson, Birte
in: F E B S Journal, vol: 276, issue: 24, pages: 7353-7365

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2009     |    DOI: https://doi.org/10.1111/j.1742-4658.2009.07445.x