DTU Sundhedsteknologi
DTU Bioinformatik
Valborg Gudmundsdottir

Valborg Gudmundsdottir

Postdoc

Institut for Sundhedsteknologi

Danmarks Tekniske Universitet

Kemitorvet

Bygning 208, rum 019

2800 Kgs. Lyngby

Tlf.
Tlf.
Mobil
Fax 45 93 15 85
E-mail vgud@dtu.dk
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2018
 

A computational framework to integrate high-throughput '-omics' datasets for the identification of potential mechanistic links

Pedersen, Helle Krogh ; Forslund, Sofia K ; Gudmundsdottir, Valborg ; Petersen, Anders Østergaard ; Hildebrand, Falk ; Hyötyläinen, Tuulia ; Nielsen, Trine ; Hansen, Torben ; Bork, Peer ; Ehrlich, S Dusko ; Brunak, Søren ; Oresic, Matej ; Pedersen, Oluf ; Nielsen, Henrik Bjørn
in: Nature Protocols, vol: 13, pages: 2781-2800

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: https://doi.org/10.1038/s41596-018-0064-z

  PDF

Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

Gudmundsdottir, Valborg ; Pedersen, Helle Krogh ; Allebrandt, Karla Viviani ; Brorsson, Caroline Anna ; van Leeuwen, Nienke ; Banasik, Karina ; Mahajan, Anubha ; Groves, Christopher J ; van de Bunt, Martijn ; Dawed, Adem Y ; Fritsche, Andreas ; Staiger, Harald ; Simonis-Bik, Annemarie M C ; Deelen, Joris ; Kramer, Mark H H ; Dietrich, Axel ; Hübschle, Thomas ; Willemsen, Gonneke ; Häring, Hans-Ulrich ; de Geus, Eco J C ; Boomsma, Dorret I ; Eekhoff, Elisabeth M W ; Ferrer, Jorge ; McCarthy, Mark I ; Pearson, Ewan R ; Gupta, Ramneek ; Brunak, Søren ; 't Hart, Leen M
in: P L o S One, vol: 13, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: https://doi.org/10.1371/journal.pone.0189886

  PDF

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

Molnos, Sophie ; Wahl, Simone ; Haid, Mark ; Eekhoff, E. Marelise W. ; Pool, René ; Floegel, Anna ; Deelen, Joris ; Much, Daniela ; Prehn, Cornelia ; Breier, Michaela ; Draisma, Harmen H. ; van Leeuwen, Nienke ; Simonis-Bik, Annemarie M.C. ; Jonsson, Anna Elisabet ; Willemsen, Gonneke ; Bernigau, Wolfgang ; Wang-Sattler, Rui ; Suhre, Karsten ; Peters, Annette ; Thorand, Barbara ; Herder, Christian ; Rathmann, Wolfgang ; Roden, Michael ; Gieger, Christian ; Kramer, Mark H.H. ; van Heemst, Diana ; Pedersen, Helle Krogh ; Gudmundsdottir, Valborg ; Schulze, Matthias B. ; Pischon, Tobias ; de Geus, Eco J.C. ; Boeing, Heiner ; Boomsma, Dorret I. ; Ziegler, Anette G. ; Slagboom, P. Eline ; Hummel, Sandra ; Beekman, Marian ; Grallert, Harald ; Brunak, Søren ; McCarthy, Mark I. ; Gupta, Ramneek ; Pearson, Ewan R. ; Adamski, Jerzy ; 'T Hart, Leen M.
in: Diabetologia, vol: 61, pages: 117-129

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: https://doi.org/10.1007/s00125-017-4436-7

2017
  PDF

Clustering on baseline clinical variables identifies subgroups of type 2 diabetes patients with different rate of progression over 18 months: a DIRECT study

Brorsson, Caroline Anna ; Pedersen, H. Krogh ; Gudmundsdottir, Valborg ; Mari, A. ; Kurbasic, A. ; Vinuela, A. ; Fernandez, J. ; Mahajan, A. ; Gupta, R. ; Dermitzakis, E. ; MacCarthy, M. ; Franks, P. ; Pearson, E. ; Brunak, Søren
in: Diabetologia, vol: 60, issue: Suppl. 1, pages: S117
Presented at:
53rd EASD Annual Meeting of the European Association for the Study of Diabetes

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    År: 2017

 

Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis

Crèvecoeur, Inne ; Gudmundsdottir, Valborg ; Vig, Saurabh ; Marques Câmara Sodré, Fernanda ; D'Hertog, Wannes ; Fierro, Ana Carolina ; Van Lommel, Leentje ; Gysemans, Conny ; Marchal, Kathleen ; Waelkens, Etienne ; Schuit, Frans ; Brunak, Søren ; Overbergh, Lut ; Mathieu, Chantal
in: Diabetologia, vol: 60, issue: 3, pages: 475-489

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: https://doi.org/10.1007/s00125-016-4191-1

  PDF

Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes

Pedersen, Helle Krogh ; Gudmundsdottir, Valborg ; Brunak, Søren
in: Frontiers in Genetics, vol: 8

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2017     |    DOI: https://doi.org/10.3389/fgene.2017.00043

2016
 

Human gut microbes impact host serum metabolome and insulin sensitivity

Pedersen, Helle Krogh ; Gudmundsdottir, Valborg ; Nielsen, Henrik Bjørn ; Hyotylainen, Tuulia ; Nielsen, Trine ; Jensen, Benjamin A. H. ; Forslund, Kristoffer ; Hildebrand, Falk ; Prifti, Edi ; Falony, Gwen ; Le Chatelier, Emmanuelle ; Levenez, Florence ; Dore, Joel ; Mattila, Ismo ; Plichta, Damian Rafal ; Poho, Paivi ; Hellgren, Lars ; Arumugam, Manimozhiyan ; Sunagawa, Shinichi ; Vieira-Silva, Sara ; Jørgensen, Torben ; Holm, Jacob Bak ; Trost, Kajetan ; Kristiansen, Karsten ; Pedersen, Susanne Brix ; Raes, Jeroen ; Wang, Jun ; Hansen, Torben ; Bork, Peer ; Brunak, Søren ; Oresic, Matej ; Ehrlich, S. Dusko ; Pedersen, Oluf
in: Nature, vol: 535, issue: 7612, pages: 376-381

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2016     |    DOI: https://doi.org/10.1038/nature18646

2015
 

A proteomic study of the regulatory role for STAT-1 in cytokine-induced beta-cell death

Rondas, Dieter ; Gudmundsdottir, Valborg ; D’Hertog, Wannes ; Crèvecoeur, Inne ; Waelkens, Etienne ; Brunak, Søren ; Mathieu, Chantal ; Overbergh, Lut
in: Proteomics - Clinical Applications, vol: 9, issue: 9-10, pages: 938-952

Type: Journal article (Peer reviewed)

Status: E-pub ahead of print     |    År: 2015     |    DOI: https://doi.org/10.1002/prca.201400124

 

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

Forslund, Kristoffer ; Hildebrand, Falk  ; Nielsen, Trine N. ; Falony, Gwen ; Le Chatelier, Emmanuelle ; Sunagawa, Shinichi ; Prifti, Edi ; Vieira-Silva, Sara ; Gudmundsdottir, Valborg ; Pedersen, Helle Krogh ; Arumugam, Manimozhiyan ; Kristiansen, Karsten ; Yvonne Voig, Anita ; Vestergaard, Henrik ; Hercog, Rajna ; Costea, Paul Igor ; Kultima, Jens Roat ; Li, Junhua ; Jørgensen, Torben ; Levenez, Florence ; Dore, Joël ; Nielsen, Henrik Bjørn ; Brunak, Søren ; Raes, Jeroen ; Hansen, Torben ; Wang, Jun ; Ehrlich, S. Dusko ; Bork, Peer ; Pedersen, Oluf
in: Nature, vol: 528, issue: 7581, pages: 262-266

Type: Letter (Peer reviewed)

Status: Published     |    År: 2015     |    DOI: https://doi.org/10.1038/nature15766