Sang Yup Lee

Sang Yup Lee

Scientific Director

DTU BIOSUSTAIN
Novo Nordisk Foundation Center for Biosustainability

Danmarks Tekniske Universitet

Kemitorvet

Bygning 220, rum x

2800 Kgs. Lyngby

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Publikationer
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2020
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Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast

Jakočiūnas, Tadas ; Klitgaard, Andreas K. ; Kontou, Eftychia Eva ; Nielsen, Julie Bang ; Thomsen, Emil ; Romero Suarez, David ; Blin, Kai ; Petzold, Christopher J. ; Gin, Jennifer W. ; Tong, Yaojun ; Gotfredsen, Charlotte Held ; Charusanti, Pep ; Frandsen, Rasmus J. N. ; Weber, Tilmann ; Lee, Sang Yup ; Jensen, Michael Krogh ; Keasling, Jay D.
in: Synthetic and Systems Biotechnology, vol: 5, issue: 1, pages: 11-18

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2020     |    DOI: https://doi.org/10.1016/j.synbio.2020.01.004

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Protocols for RecET-based markerless gene knockout and integration to express heterologous biosynthetic gene clusters in Pseudomonas putida

Choi, Kyeong Rok ; Lee, Sang Yup
in: Microbial Biotechnology, vol: 13, issue: 1, pages: 199-209

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2020     |    DOI: https://doi.org/10.1111/1751-7915.13374

2019
 

A comprehensive metabolic map for production of bio-based chemicals

Lee, Sang Yup ; Kim, Hyun Uk ; Chae, Tong Un ; Cho, Jae Sung ; Kim, Je Woong ; Shin, Jae Ho ; Kim, Dong In ; Ko, Yoo Sung ; Jang, Woo Dae ; Jang, Yu Sin
in: Nature Catalysis, vol: 2, issue: 1, pages: 18-33

Type: Review (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1038/s41929-018-0212-4

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antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

Blin, Kai ; Shaw, Simon ; Steinke, Katharina ; Villebro, Rasmus ; Ziemert, Nadine ; Lee, Sang Yup ; Medema, Marnix H ; Weber, Tilmann
in: Nucleic acids research, vol: 87, issue: W2, pages: W81-W87

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1093/nar/gkz310

 

Are we there yet? How and when specific biotechnologies will improve human health

O'Day, Elizabeth ; Hosta-Rigau, Leticia ; Oyarzún, Diego A. ; Okano, Hideyuki ; de Lorenzo, Víctor ; von Kameke, Conrad ; Alsafar, Habiba ; Cao, Cong ; Chen, Guo-Qiang ; Ji, Weizhi ; Roberts, Richard J. ; Ronaghi, Mostafa ; Yeung, Karen ; Zhang, Feng ; Lee, Sang Yup
in: Biotechnology Journal, vol: 14, issue: 1, pages: 11

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1002/biot.201800195

 

CRISPR/Cas-based genome engineering in natural product discovery

Tong, Yaojun ; Weber, Tilmann ; Lee, Sang Yup
in: Natural Product Reports, vol: 36, issue: 9, pages: 1225-1372

Type: Review (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1039/C8NP00089A

 

Genome-Scale Metabolic Reconstruction of Actinomycetes for Antibiotics Production

Mohite, Omkar Satyavan ; Weber, Tilmann ; Kim, Hyun Uk ; Lee, Sang Yup
in: Biotechnology Journal, vol: 14, issue: 1

Type: Review (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1002/biot.201800377

 

Synthetic biology and metabolic engineering of actinomycetes for natural product discovery

Palazzotto, Emilia ; Tong, Yaojun ; Lee, Sang Yup ; Weber, Tilmann
in: Biotechnology Advances, vol: 37, issue: 6

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1016/j.biotechadv.2019.03.005

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The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters

Blin, Kai ; Pascal Andreu, Victòria ; de Los Santos, Emmanuel L C ; Del Carratore, Francesco ; Lee, Sang Yup ; Medema, Marnix H. ; Weber, Tilmann
in: Nucleic acids research, vol: 47, issue: D1, pages: D625–D630

Type: Journal article (Peer reviewed)

Status: Published     |    År: 2019     |    DOI: https://doi.org/10.1093/nar/gky1060

2018
 

CRISPR-Cas9 Toolkit for Actinomycete Genome Editing

Tong, Yaojun ; Robertsen, Helene Lunde ; Blin, Kai ; Weber, Tilmann ; Lee, Sang Yup
part of: Synthetic Metabolic Pathways, pages: 163-184, 2018

Type: Book chapter (Peer reviewed)

Status: Published     |    År: 2018     |    DOI: https://doi.org/10.1007/978-1-4939-7295-1_11