Claus Helix Nielsen

Claus Helix Nielsen

Associate Professor

DTU ENVIRONMENT
Department of Environmental Engineering

Technical University of Denmark

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Keywords Lipid-protein interactions | Biomimetic membranes | Membrane transport | Membrane channel proteins | Electrophysiology | Spectroscopy

My research is centered on lipid-protein interactions. In particular how the hydrophobic coupling between transmembrane proteins and their host bilayer may regulate protein function through changes in the bilayer mechanical properties. Also how membrane mechanical properties affect overall membrane dynamics (e.g. vesiculation).  The technological goal of my research is to create biomimetic membranes for biosensor and separation (filtering) applications. Our techniques are electrophysiology, fluorescence-, electron paramagnetic-, and Raman spectroscopy, as well as molecular dynamics and continuum modeling.