Ramneek Gupta

Ramneek Gupta

Associate Professor

DTU BIOINFORMATICS
Department of Bio and Health Informatics

Disease Intelligence and Molecular Evolution
DTU Bioinformatics Employees

Technical University of Denmark

Kemitorvet

Building 208, room 021

2800 Kgs. Lyngby

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Fax +45 45 93 15 85
E-mail rg@bioinformatics.dtu.dk
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2019
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial

Roager, Henrik Munch ; Vogt, Josef Korbinian ; Kristensen, Mette ; Hansen, Lea Benedicte S ; Ibrügger, Sabine ; Mærkedahl, Rasmus B ; Bahl, Martin Iain ; Lind, Mads Vendelbo ; Nielsen, Rikke Linnemann ; Frøkiær, Hanne ; Gøbel, Rikke Juul ; Landberg, Rikard ; Ross, Alastair B ; Brix, Susanne ; Holck, Jesper ; Meyer, Anne S. ; Sparholt, Morten H ; Christensen, Anders F ; Carvalho, Vera ; Holst, Jens Juul ; Rumessen, Jüri Johannes ; Linneberg, Allan ; Sicheritz-Pontén, Thomas ; Dalgaard, Marlene Danner ; Blennow, Andreas ; Frandsen, Henrik Lauritz ; Villas-Bôas, Silas Granato ; Kristiansen, Karsten ; Vestergaard, Henrik ; Hansen, Torben ; Ekstrøm, Claus T ; Ritz, Christian ; Nielsen, Henrik Bjørn ; Pedersen, Oluf Borbye ; Gupta, Ramneek ; Lauritzen, Lotte ; Licht, Tine Rask
in: Gut, vol: 68, issue: 1, pages: 83-93

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1136/gutjnl-2017-314786

2018
 

Accurate genotyping across variant classes and lengths using variant graphs

Sibbesen, Jonas Andreas ; Maretty, Lasse ; Jensen, Jacob Malte ; Petersen, Bent ; Liu, Siyang ; Villesen, Palle ; Skov, Laurits ; Belling, Kirstine ; Theil Have, Christian ; Gonzalez-Izarzugaza, Jose Maria ; Grosjean, Marie ; Bork-Jensen, Jette ; Grove, Jakob ; Dam-Als, Thomas ; Huang, Shujia ; Chang, Yuqi ; Xu, Ruiqi ; Ye, Weijian ; Rao, Junhua ; Guo, Xiaosen ; Sun, Jihua ; Cao, Hongzhi ; Ye, Chen ; van Beusekom, Johan ; Espeseth, Thomas ; Flindt, Esben ; Friborg, Rune M. ; Halager, Anders Egerup ; Le Hellard, Stephanie ; Hultman, Christina M. ; Lescai, Francesco ; Li, Shengting ; Lund, Ole ; Løngren, Peter ; Mailund, Thomas ; Matey-Hernandez, María Luisa ; Mors, Ole ; Pedersen, Christian N. S. ; Sicheritz-Pontén, Thomas ; Sullivan, Patrick ; Ali , Syed ; Westergaard, David ; Yadav, Rachita ; Li, Ning ; Xu, Xun ; Hansen, Torben ; Krogh, Anders ; Bolund, Lars ; Sørensen, Thorkild I. A. ; Pedersen, Oluf ; Gupta, Ramneek ; Rasmussen, Simon ; Besenbacher, Søren ; Børglum, Anders D. ; Wang, Jun ; Eiberg, Hans ; Kristiansen, Karsten ; Brunak, Søren ; Schierup, Mikkel Heide
in: Nature Genetics

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1038/s41588-018-0145-5

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A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults

Hansen, Lea B. S. ; Roager, Henrik M. ; Søndertoft, Nadja B. ; Gøbel, Rikke J. ; Kristensen, Mette ; Vallès-Colomer, Mireia ; Vieira-Silva, Sara ; Ibrügger, Sabine ; Lind, Mads V. ; Mærkedahl, Rasmus B. ; Bahl, Martin Iain ; Madsen, Mia L ; Havelund, Jesper ; Falony, Gwen ; Tetens, Inge ; Nielsen, Trine ; Allin, Kristine H. ; Frandsen, Henrik L ; Hartmann, Bolette ; Holst, Jens Juul ; Sparholt, Morten H. ; Holck, Jesper ; Blennow, Andreas ; Moll, Janne Marie ; Meyer, Anne S. ; Hoppe, Camilla ; Poulsen, Jørgen H. ; Carvalho, Vera ; Sagnelli, Domenico ; Dalgaard, Marlene Danner ; Christensen, Anders F. ; Lydolph, Magnus Christian ; Ross, Alastair B ; Villas-Bôas, Silas ; Brix, Susanne ; Sicheritz-Pontén, Thomas ; Buschard, Karsten ; Linneberg, Allan ; Rumessen, Jüri J. ; Ekstrøm, Claus T. ; Ritz, Christian ; Kristiansen, Karsten ; Nielsen, H. Bjørn ; Vestergaard, Henrik ; Færgeman, Nils J. ; Raes, Jeroen ; Frøkiær, Hanne ; Hansen, Torben ; Gupta, Ramneek ; Licht, Tine Rask ; Pedersen, Oluf
in: Nature Communications, vol: 9, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1038/s41467-018-07019-x

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Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios

Matey-Hernandez, María Luisa ; Maretty, Lasse ; Jensen, Jacob Malte ; Petersen, Bent ; Andreas Sibbesen, Jonas ; Liu, Siyang ; Villesen, Palle ; Skov, Laurits ; Belling, Kirstine ; Theil Have, Christian ; Gonzalez-Izarzugaza, Jose Maria ; Grosjean, Marie ; Bork-Jensen, Jette ; Grove, Jakob ; Als, Thomas D. ; Huang, Shujia ; Chang, Yuqi ; Xu, Ruiqi ; Ye, Weijian ; Rao, Junhua ; Guo, Xiaosen ; Sun, Jihua ; Cao, Hongzhi ; Ye, Chen ; Beusekom, Johan v. ; Espeseth, Thomas ; Flindt, Esben N. ; Friborg, Rune M. ; Halager, Anders Egerup ; Le Hellard, Stephanie ; Hultman, Christina M. ; Lescai, Francesco ; Li, Shengting ; Lund, Ole ; Løngren, Peter ; Mailund, Thomas ; Mors, Ole ; Pedersen, Christian N. S. ; Sicheritz-Pontén, Thomas ; Sullivan, Patrick F. ; Ali , Syed ; Westergaard, David ; Yadav, Rachita ; Li, Ning ; Xu, Xun ; Hansen, Torben ; Krogh, Anders ; Bolund, Lars ; Sørensen, Thorkild I. A. ; Pedersen, Oluf ; Gupta, Ramneek ; Besenbacher, Søren ; Børglum, Anders D. ; Wang, Jun ; Eiberg, Hans ; Kristiansen, Karsten ; Brunak, Søren ; Schierup, Mikkel Heide ; Izarzugaza, Jose M. G.
in: B M C Bioinformatics, vol: 19

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1186/s12859-018-2239-6

 

Genetic predisposition to PEG-asparaginase hypersensitivity in children treated according to NOPHO ALL2008

Højfeldt, Sofie G. ; Wolthers, Benjamin O. ; Tulstrup, Morten ; Abrahamsson, Jonas ; Gupta, Ramneek ; Harila-Saari, Arja ; Heyman, Mats ; Henriksen, Louise T. ; Jónsson, Òlafur G. ; Lähteenmäki, Päivi M. ; Lund, Bendik ; Pruunsild, Kaie ; Vaitkeviciene, Goda ; Schmiegelow, Kjeld ; Albertsen, Birgitte K.
in: British Journal of Haematology

Type: Journal article (Peer reviewed)

Status: Accepted/In press     |    Year: 2018     |    DOI: https://doi.org/10.1111/bjh.15660

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Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

Gudmundsdottir, Valborg ; Pedersen, Helle Krogh ; Allebrandt, Karla Viviani ; Brorsson, Caroline Anna ; van Leeuwen, Nienke ; Banasik, Karina ; Mahajan, Anubha ; Groves, Christopher J ; van de Bunt, Martijn ; Dawed, Adem Y ; Fritsche, Andreas ; Staiger, Harald ; Simonis-Bik, Annemarie M C ; Deelen, Joris ; Kramer, Mark H H ; Dietrich, Axel ; Hübschle, Thomas ; Willemsen, Gonneke ; Häring, Hans-Ulrich ; de Geus, Eco J C ; Boomsma, Dorret I ; Eekhoff, Elisabeth M W ; Ferrer, Jorge ; McCarthy, Mark I ; Pearson, Ewan R ; Gupta, Ramneek ; Brunak, Søren ; 't Hart, Leen M
in: P L o S One, vol: 13, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1371/journal.pone.0189886

 

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

Molnos, Sophie ; Wahl, Simone ; Haid, Mark ; Eekhoff, E. Marelise W. ; Pool, René ; Floegel, Anna ; Deelen, Joris ; Much, Daniela ; Prehn, Cornelia ; Breier, Michaela ; Draisma, Harmen H. ; van Leeuwen, Nienke ; Simonis-Bik, Annemarie M.C. ; Jonsson, Anna Elisabet ; Willemsen, Gonneke ; Bernigau, Wolfgang ; Wang-Sattler, Rui ; Suhre, Karsten ; Peters, Annette ; Thorand, Barbara ; Herder, Christian ; Rathmann, Wolfgang ; Roden, Michael ; Gieger, Christian ; Kramer, Mark H.H. ; van Heemst, Diana ; Pedersen, Helle Krogh ; Gudmundsdottir, Valborg ; Schulze, Matthias B. ; Pischon, Tobias ; de Geus, Eco J.C. ; Boeing, Heiner ; Boomsma, Dorret I. ; Ziegler, Anette G. ; Slagboom, P. Eline ; Hummel, Sandra ; Beekman, Marian ; Grallert, Harald ; Brunak, Søren ; McCarthy, Mark I. ; Gupta, Ramneek ; Pearson, Ewan R. ; Adamski, Jerzy ; 'T Hart, Leen M.
in: Diabetologia, vol: 61, pages: 117-129

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1007/s00125-017-4436-7

 

NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia

Tulstrup, Morten ; Grosjean, Marie ; Nielsen, Stine Nygaard ; Grell, Kathrine ; Wolthers, Benjamin Ole ; Wegener, Peder Skov ; Jonsson, Olafur Gisli ; Lund, Bendik ; Harila-Saari, Arja ; Abrahamsson, Jonas ; Vaitkeviciene, Goda ; Pruunsild, Kaie ; Toft, Nina ; Holm, Mette ; Hulegårdh, Erik ; Liestøl, Sigurd ; Griskevicius, Laimonas ; Punab, Mari ; Wang, Jinhua ; Carroll, William L. ; Zhang, Zeyu ; Dalgaard, Marlene D. ; Gupta, Ramneek ; Nersting, Jacob ; Schmiegelow, Kjeld
in: Leukemia, vol: 32, pages: 2527-2535

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1038/s41375-018-0245-3

 

Prediction of liver fat in people with and without type 2 diabetes: an IMI DIRECT study

Pasdar, N. Atabaki ; Ohlsson, M. ; Vinuela, A. ; Frau, F. ; Koivula, R. ; Fernández, J ; Thomas, E. ; Mari, A. ; Gupta, R. ; Kurbasic, A. ; Pearson, E. ; Pavo, I. ; Bell, J. ; Franks, Paul W.
in: Diabetologia, vol: 61, issue: 1S, pages: S581

Type: Conference abstract in journal (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1007/s00125-018-4693-0

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The governance structure for data access in the DIRECT consortium: an innovative medicines initiative (IMI) project

Teare, Harriet J. A. ; De Masi, Federico ; Banasik, Karina ; Barnett, Anna ; Herrgard, Sanna ; Jablonka, Bernd ; Postma, Jacqueline W. M. ; McDonald, Timothy J. ; Forgie, Ian ; Chmura, Piotr Jaroslaw ; Rydzka, Emil K. ; Gupta, Ramneek ; Brunak, Søren ; Pearson, Ewan ; Kaye, Jane
in: Life Sciences, Society and Policy, vol: 14

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.1186/s40504-018-0083-0