Søren Brunak

Søren Brunak

Professor

DTU BIOINFORMATICS
Department of Bio and Health Informatics

Integrative Systems Biology
DTU Bioinformatics Employees

Technical University of Denmark

Kemitorvet

Building 208, room 016

2800 Kgs. Lyngby

Ph.
Ph.
Fax +45 45 93 15 85
E-mail brunak@bioinformatics.dtu.dk
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2018
 

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

Molnos, Sophie ; Wahl, Simone ; Haid, Mark ; Eekhoff, E. Marelise W. ; Pool, René ; Floegel, Anna ; Deelen, Joris ; Much, Daniela ; Prehn, Cornelia ; Breier, Michaela ; Draisma, Harmen H. ; van Leeuwen, Nienke ; Simonis-Bik, Annemarie M.C. ; Jonsson, Anna Elisabet ; Willemsen, Gonneke ; Bernigau, Wolfgang ; Wang-Sattler, Rui ; Suhre, Karsten ; Peters, Annette ; Thorand, Barbara ; Herder, Christian ; Rathmann, Wolfgang ; Roden, Michael ; Gieger, Christian ; Kramer, Mark H.H. ; van Heemst, Diana ; Pedersen, Helle Krogh ; Gudmundsdottir, Valborg ; Schulze, Matthias B. ; Pischon, Tobias ; de Geus, Eco J.C. ; Boeing, Heiner ; Boomsma, Dorret I. ; Ziegler, Anette G. ; Slagboom, P. Eline ; Hummel, Sandra ; Beekman, Marian ; Grallert, Harald ; Brunak, Søren ; McCarthy, Mark I. ; Gupta, Ramneek ; Pearson, Ewan R. ; Adamski, Jerzy ; 'T Hart, Leen M.
in: Diabetologia (ISSN: 0012-186X), vol: 61, pages: 117-129, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1007/s00125-017-4436-7

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miRandola 2017: a curated knowledge base of non-invasive biomarkers

Russo, Francesco ; Di Bella, Sebastiano ; Vannini, Federica ; Berti, Gabriele ; Scoyni, Flavia ; Cook, Helen Victoria ; Santos, Alberto ; Nigita, Giovanni ; Bonnici, Vincenzo ; Laganà, Alessandro ; Geraci, Filippo ; Pulvirenti, Alfredo ; Giugno, Rosalba ; De Masi, Federico ; Belling, Kirstine González-Izarzugaza ; Jensen, Lars Juhl ; Brunak, Søren ; Pellegrini, Marco ; Ferro, Alfredo
in: Nucleic Acids Research (ISSN: 0305-1048), vol: 46, issue: D1, pages: D354-D359, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1093/nar/gkx854

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Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

Gudmundsdottir, Valborg ; Pedersen, Helle Krogh ; Allebrandt, Karla Viviani ; Brorsson, Caroline Anna ; van Leeuwen, Nienke ; Banasik, Karina ; Mahajan, Anubha ; Groves, Christopher J ; van de Bunt, Martijn ; Dawed, Adem Y ; Fritsche, Andreas ; Staiger, Harald ; Simonis-Bik, Annemarie M C ; Deelen, Joris ; Kramer, Mark H H ; Dietrich, Axel ; Hübschle, Thomas ; Willemsen, Gonneke ; Häring, Hans-Ulrich ; de Geus, Eco J C ; Boomsma, Dorret I ; Eekhoff, Elisabeth M W ; Ferrer, Jorge ; McCarthy, Mark I ; Pearson, Ewan R ; Gupta, Ramneek ; Brunak, Søren ; 't Hart, Leen M
in: P L o S One (ISSN: 1932-6203), vol: 13, issue: 1, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1371/journal.pone.0189886

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Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

Kristensen, David Møbjerg ; Desdoits-Lethimonier, Christèle ; Mackey, Abigail L ; Dalgaard, Marlene Danner ; De Masi, Federico ; Munkbøl, Cecilie Hurup ; Styrishave, Bjarne ; Antignac, Jean-Philippe ; Le Bizec, Bruno ; Platel, Christian ; Hay-Schmidt, Anders ; Jensen, Tina Kold ; Lesné, Laurianne ; Mazaud-Guittot, Séverine ; Kristiansen, Karsten ; Brunak, Søren ; Kjær, Michael ; Juul, Anders Christian ; Jégou, Bernard
in: Proceedings of the National Academy of Sciences of the United States of America (ISSN: 0027-8424), vol: 115, issue: 17, pages: E715-E724, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1073/pnas.1715035115

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Analysis of a gene panel for targeted sequencing of colorectal cancer samples

Jensen, Klaus Højgaard ; Gonzalez-Izarzugaza, Jose Maria ; Juncker, Agnieszka ; Borup Hansen, Rasmus ; Frøstrup Hansen, Torben ; Timshel, Pascal ; Blondal, Thorarinn ; Jensen, Thomas Skøt ; Rygaard-Hjalsted, Eske ; Mouritzen, Peter ; Thorsen, Michael ; Wernersson, Rasmus ; Nielsen, Henrik Bjørn ; Jakobsen, Anders ; Brunak, Søren ; Brandt Sørensen, Flemming
in: OncoTarget (ISSN: 1949-2553), vol: 9, issue: 10, pages: 9043-9060, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.18632/oncotarget.24138

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A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts

Westergaard, David ; Stærfeldt, Hans Henrik ; Tønsberg, Christian ; Jensen, Lars Juhl ; Brunak, Søren
in: P L o S Computational Biology (Online) (ISSN: 1553-7358), vol: 14, issue: 2, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1371/journal.pcbi.1005962

 

Accurate genotyping across variant classes and lengths using variant graphs

Sibbesen, Jonas Andreas ; Maretty, Lasse ; Jensen, Jacob Malte ; Petersen, Bent ; Liu, Siyang ; Villesen, Palle ; Skov, Laurits ; Belling, Kirstine González-Izarzugaza ; Theil Have, Christian ; Gonzalez-Izarzugaza, Jose Maria ; Grosjean, Marie ; Bork-Jensen, Jette ; Grove, Jakob ; Dam-Als, Thomas ; Huang, Shujia ; Chang, Yuqi ; Xu, Ruiqi ; Ye, Weijian ; Rao, Junhua ; Guo, Xiaosen ; Sun, Jihua ; Cao, Hongzhi ; Ye, Chen ; van Beusekom, Johan ; Espeseth, Thomas ; Flindt, Esben ; Friborg, Rune M. ; Halager, Anders Egerup ; Le Hellard, Stephanie ; Hultman, Christina M. ; Lescai, Francesco ; Li, Shengting ; Lund, Ole ; Løngren, Peter ; Mailund, Thomas ; Matey-Hernandez, María Luisa ; Mors, Ole ; Pedersen, Christian N. S. ; Sicheritz-Pontén, Thomas ; Sullivan, Patrick ; Qaswar Ali Shah, Syed ; Westergaard, David ; Yadav, Rachita ; Li, Ning ; Xu, Xun ; Hansen, Torben ; Krogh, Anders ; Bolund, Lars ; Sørensen, Thorkild I. A. ; Pedersen, Oluf ; Gupta, Ramneek ; Rasmussen, Simon ; Besenbacher, Søren ; Børglum, Anders D. ; Wang, Jun ; Eiberg, Hans ; Kristiansen, Karsten ; Brunak, Søren ; Schierup, Mikkel Heide
in: Nature Genetics (ISSN: 1061-4036), 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1038/s41588-018-0145-5

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Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios

Matey-Hernandez, María Luisa ; Maretty, Lasse ; Jensen, Jacob Malte ; Petersen, Bent ; Andreas Sibbesen, Jonas ; Liu, Siyang ; Villesen, Palle ; Skov, Laurits ; Belling, Kirstine González-Izarzugaza ; Theil Have, Christian ; Gonzalez-Izarzugaza, Jose Maria ; Grosjean, Marie ; Bork-Jensen, Jette ; Grove, Jakob ; Als, Thomas D. ; Huang, Shujia ; Chang, Yuqi ; Xu, Ruiqi ; Ye, Weijian ; Rao, Junhua ; Guo, Xiaosen ; Sun, Jihua ; Cao, Hongzhi ; Ye, Chen ; Beusekom, Johan v. ; Espeseth, Thomas ; Flindt, Esben N. ; Friborg, Rune M. ; Halager, Anders Egerup ; Le Hellard, Stephanie ; Hultman, Christina M. ; Lescai, Francesco ; Li, Shengting ; Lund, Ole ; Løngren, Peter ; Mailund, Thomas ; Mors, Ole ; Pedersen, Christian N. S. ; Sicheritz-Pontén, Thomas ; Sullivan, Patrick F. ; Qaswar Ali Shah, Syed ; Westergaard, David ; Yadav, Rachita ; Li, Ning ; Xu, Xun ; Hansen, Torben ; Krogh, Anders ; Bolund, Lars ; Sørensen, Thorkild I. A. ; Pedersen, Oluf ; Gupta, Ramneek ; Besenbacher, Søren ; Børglum, Anders D. ; Wang, Jun ; Eiberg, Hans ; Kristiansen, Karsten ; Brunak, Søren ; Schierup, Mikkel Heide
in: B M C Bioinformatics (ISSN: 1471-2105), vol: 19, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1186/s12859-018-2239-6

2017
 

Combinatorial Drug Screening Identifies Ewing Sarcoma-specific Sensitivities

Radic-Sarikas, Branka ; Tsafou, Kalliopi P ; Emdal, Kristina B. ; Papamarkou, Theodore ; Huber, Kilian V. M. ; Mutz, Cornelia ; Toretsky, Jeffrey A ; Bennett, Keiryn L. ; Olsen, Jesper V. ; Brunak, Søren ; Kovar, Heinrich ; Superti-Furga, Giulio
in: Molecular Cancer Therapeutics (ISSN: 1535-7163), vol: 16, issue: 1, pages: 88-101, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1158/1535-7163.MCT-16-0235

 

Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis

Crèvecoeur, Inne ; Gudmundsdottir, Valborg ; Vig, Saurabh ; Marques Câmara Sodré, Fernanda ; D'Hertog, Wannes ; Fierro, Ana Carolina ; Van Lommel, Leentje ; Gysemans, Conny ; Marchal, Kathleen ; Waelkens, Etienne ; Schuit, Frans ; Brunak, Søren ; Overbergh, Lut ; Mathieu, Chantal
in: Diabetologia (ISSN: 0012-186X), vol: 60, issue: 3, pages: 475-489, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1007/s00125-016-4191-1