Sang Yup Lee

Sang Yup Lee

Scientific Director

DTU BIOSUSTAIN
Novo Nordisk Foundation Center for Biosustainability

Technical University of Denmark

Kemitorvet

Building 220, room x

2800 Kgs. Lyngby

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2018
 

CRISPR-Cas9 Toolkit for Actinomycete Genome Editing

Tong, Yaojun ; Robertsen, Helene Lunde ; Blin, Kai ; Weber, Tilmann ; Lee, Sang Yup
part of: Synthetic Metabolic Pathways (ISBN: 978-1-4939-7294-4), pages: 163-184, 2018,

Type: Book chapter (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1007/978-1-4939-7295-1_11

  PDF

Filling the Gaps in the Kirromycin Biosynthesis: Deciphering the Role of Genes Involved in Ethylmalonyl-CoA Supply and Tailoring Reactions

Robertsen, Helene Lunde ; Musiol-Kroll, Ewa Maria ; Ding, Ling ; Laiple, Kristina J. ; Hofeditz, Torben ; Wohlleben, Wolfgang ; Lee, Sang Yup ; Grond, Stephanie ; Weber, Tilmann
in: Scientific Reports (ISSN: 2045-2322), vol: 8, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1038/s41598-018-21507-6

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The power of synthetic biology for bioproduction, remediation and pollution control

de Lorenzo, Víctor ; Prather, Kristala L.J. ; Chen, Guo-Qiang ; O'Day, Elizabeth ; von Kameke, Conrad ; Oyarzún, Diego A. ; Hosta-Rigau, Leticia ; Alsafar, Habiba ; Cao, Cong ; Ji, Weizhi ; Okano, Hideyuki ; Roberts, Richard J. ; Ronaghi, Mostafa ; Yeung, Karen ; Zhang, Feng ; Lee, Sang Yup
in: E M B O Reports (ISSN: 1469-221X), vol: 19, issue: 4, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.15252/embr.201745658

 

Markerless gene knockout and integration to express heterologous biosynthetic gene clusters in Pseudomonas putida

Choi, Kyeong Rok ; Cho, Jae Sung ; Cho, In Jin ; Park, Dahyeon ; Lee, Sang Yup
in: Metabolic Engineering (ISSN: 1096-7176), vol: 47, pages: 463-474, 2018

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: http://dx.doi.org/10.1016/j.ymben.2018.05.003

2017
  PDF

The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters

Blin, Kai ; Medema, Marnix H. ; Kottmann, Renzo ; Lee, Sang Yup ; Weber, Tilmann
in: Nucleic Acids Research (ISSN: 0305-1048), vol: 45, issue: D1, pages: D555-D559, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1093/nar/gkw960

 

Polyketide Bioderivatization Using the Promiscuous Acyltransferase KirCII

Musiol-Kroll, Ewa Maria ; Zubeil, Florian ; Schafhauser, Thomas ; Härtner, Thomas ; Kulik, Andreas ; McArthur, John ; Koryakina, Irina ; Wohlleben, Wolfgang ; Grond, Stephanie ; Williams, Gavin J. ; Lee, Sang Yup ; Weber, Tilmann
in: A C S Synthetic Biology (ISSN: 2161-5063), vol: 6, issue: 3, pages: 421-427, 2017

Type: Letter (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1021/acssynbio.6b00341

  PDF

Designing sgRNAs with CRISPy web

Blin, Kai ; Lee, Sang Yup ; Weber, Tilmann
in: Lab Times (ISSN: 1864-2381), issue: 1, pages: 53, 2017

Type: Journal article

Status: Published     |    Year: 2017

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antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification

Blin, Kai ; Wolf, Thomas ; Chevrette, Marc G. ; Lu, Xiaowen ; Schwalen, Christopher J. ; Kautsar, Satria A. ; Suarez Duran, Hernando G. ; de Los Santos, Emmanuel L. C. ; Kim, Hyun Uk ; Nave, Mariana ; Dickschat, Jeroen S. ; Mitchell, Douglas A. ; Shelest, Ekaterina ; Breitling, Rainer ; Takano, Eriko ; Lee, Sang Yup ; Weber, Tilmann ; Medema, Marnix H.
in: Nucleic Acids Research (ISSN: 0305-1048), vol: 45, pages: W36-W41, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1093/nar/gkx319

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Dissemination of antibiotic resistance genes from antibiotic producers to pathogens

Jiang, Xinglin ; Ellabaan, Mostafa M Hashim ; Charusanti, Pep ; Munck, Christian ; Blin, Kai ; Tong, Yaojun ; Weber, Tilmann ; Sommer, Morten Otto Alexander ; Lee, Sang Yup
in: Nature Communications (ISSN: 2041-1723), vol: 8, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1038/ncomms15784

 

Harnessing the respiration machinery for high-yield production of chemicals in metabolically engineered Lactococcus lactis

Liu, Jianming ; Wang, Zhihao ; Kandasamy, Vijayalakshmi ; Lee, Sang Yup ; Solem, Christian ; Jensen, Peter Ruhdal
in: Metabolic Engineering (ISSN: 1096-7176), vol: 44, pages: 22-29, 2017

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: http://dx.doi.org/10.1016/j.ymben.2017.09.001